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Stress-responsive self-strengthening of biomedical metals with self-tunable elastic modulus--Potential of stress-induced omega phase to improve mechanical properties

Research Project

Project/Area Number 25630004
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Materials/Mechanics of materials
Research InstitutionTohoku University

Principal Investigator

NAKAI Masaaki  東北大学, 金属材料研究所, 准教授 (20431603)

Co-Investigator(Kenkyū-buntansha) NARITA Kengo  東北大学, 金属材料研究所, 助教 (70632339)
Co-Investigator(Renkei-kenkyūsha) ISHIMOTO Takuya  大阪大学, 大学院工学研究科, 講師 (50508835)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords生体用金属材料 / チタン合金 / 変形誘起相変態 / オメガ相 / 疲労特性 / 変形誘起オメガ相変態 / 力学的特性
Outline of Final Research Achievements

In the metals with self-tunable elastic modulus developed by our group, the elastic modulus at the deformed part is increased by occurring the deformation-induced ω phase transformation. In this study, we tried to achieve the increase in strength and durability using this specific property. One of the representative metals with self-tunable elastic modulus, Ti-12Cr alloy, was used for the evaluation of fatigue properties. As the result, even though the solution treated condition, high fatigue strength could be obtained for Ti-12Cr alloy. Low durability is a weak point of biomedical β-type titanium alloys, but Ti-12Cr alloy is possible to overcome such the weak point.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (37 results)

All 2015 2014 2013 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (26 results) (of which Invited: 7 results)

  • [Journal Article] Biomedical implant devices fabricated from low Young's modulus titanium alloys with demonstrating high mechanical biocompatibility2014

    • Author(s)
      M. Niinomi and M. Nakai
    • Journal Title

      Material Matters

      Volume: 9 Pages: 39-46

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optimization of Mo content in beta-type Ti-Mo alloys for obtaining larger changeable Young's modulus during deformation for use in spinal fixation applications2014

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda, K. Cho, K. Narita and X.F. Zhao
    • Journal Title

      Mater. Sci. Forum

      Volume: 783-786 Pages: 1307-1312

    • DOI

      10.4028/www.scientific.net/msf.783-786.1307

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship between heterogeneous microstructure and fatigue strength of Ti-Nb-Ta-Zr alloy for biomedical materials subjected to aging treatments2014

    • Author(s)
      K. Narita, M. Niinomi and M. Nakai
    • Journal Title

      Mater. Sci. Forum

      Volume: 783-786 Pages: 1313-1319

    • DOI

      10.4028/www.scientific.net/msf.783-786.1313

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Deformation-induced changeable Young's modulus with high strength in β-type Ti-Cr-O alloys for spinal fixture2014

    • Author(s)
      H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K.Cho
    • Journal Title

      J. Mech. Behav. Biomed. Mater.

      Volume: 30 Pages: 205-213

    • DOI

      10.1016/j.jmbbm.2013.11.001

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of changeable Young's modulus with good mechanical properties in β-type Ti-Cr-O alloys2014

    • Author(s)
      H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Journal Title

      Key Eng. Mater.

      Volume: 575-576 Pages: 453-460

    • DOI

      10.4028/www.scientific.net/kem.575-576.453

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Optimization of Cr and O contents in beta-type Ti-Cr-O alloys for obtaining both larger changeable Young's modulus during deformation and higher strength for use in spinal fixation applications2014

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda, K. Cho, K. Narita and H.H. Liu
    • Journal Title

      Proceedings of Materials Science and Technology Conference and Exhibition 2013

      Volume: - Pages: 2991-2997

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 骨-インプラント間の弾性率差による骨形態変化2013

    • Author(s)
      新家光雄, 服部友一, 仲井正昭
    • Journal Title

      日本骨形態計測学会雑誌

      Volume: 23 Pages: 23-30

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Deformation-induced ω phase in modified Ti-29Nb-13Ta-4.6Zr alloy by Cr addition2013

    • Author(s)
      Q. Li, M. Niinomi, J. Hieda, M. Nakai and K. Cho
    • Journal Title

      Acta Biomaterialia

      Volume: 9 Issue: 8 Pages: 8027-8035

    • DOI

      10.1016/j.actbio.2013.04.032

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Improvement of Tensile and Fatigue Properties of β-Titanium Alloy while Maintaining Low Young’s Modulus through Grain Refinement and Oxygen Addition2013

    • Author(s)
      K. Cho, M. Niinomi, M. Nakai, J. Hieda and R. Kanekiyo
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 54 Issue: 10 Pages: 2000-2006

    • DOI

      10.2320/matertrans.M2013151

    • NAID

      10031201555

    • ISSN
      1345-9678, 1347-5320
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Mechanical properties of Ti-12Cr alloy with self-tunable Young's modulus for use in spinal fixation devices2013

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda and K. Cho
    • Journal Title

      Proceedings of the 8th Pacific Rim International Congress on Advanced Materials and Processing

      Volume: - Pages: 1541-1546

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Deformation induced changeable Young's modulus in ternary Ti-Cr-O alloys for spinal fixation applications2013

    • Author(s)
      H.H Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Journal Title

      Proceedings of the 8th Pacific Rim International Congress on Advanced Materials and Processing

      Volume: - Pages: 1635-1641

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 生体用β型チタン合金の疲労強度に及ぼす酸素添加の影響2015

    • Author(s)
      小原慎也, 新家光雄, 趙研, 仲井正昭, 劉恢弘
    • Organizer
      日本金属学会2015年春期(第156回)大会
    • Place of Presentation
      東京大学
    • Year and Date
      2015-03-18 – 2015-03-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Development for a spinal fixation rod with low-rigidity and high-durability2014

    • Author(s)
      K. Narita, M. Niinomi, M. Nakai and Suyalatu
    • Organizer
      The 5th International Symposium on Ad-vanced Materials Development and Inte-gration of Novel Structured Metallic and Inorganic Materials (AMDI-5) conjunction with 6th IBB Frontier Symposium
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 生体用β型チタン合金製脊椎固定器具の耐久性向上に及ぼすキャビテーションピーニングの効果2014

    • Author(s)
      仲井正昭, 新家光雄, 成田健吾, 趙研, 髙桑脩, 祖山均
    • Organizer
      軽金属学会第127回秋期大会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2014-11-15 – 2014-11-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 低弾性率β型チタン合金の実用化に向けた取り組み2014

    • Author(s)
      仲井正昭、新家光雄、成田健吾、趙研
    • Organizer
      東北大学金属材料研究所ワークショップおよび日本バイオマテリアル学会東北地域講演会「産学官連携による金属系バイオマテリアルの研究開発の最前線」
    • Place of Presentation
      東北大学
    • Year and Date
      2014-10-06 – 2014-10-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] キャビテーションピーニング処理によるβ型チタン合金製脊椎固定器具の耐久性改善2014

    • Author(s)
      成田健吾, 新家光雄, 仲井正昭, 蘇亜拉図, 祖山均, 髙桑脩
    • Organizer
      日本金属学会2014年秋期(第155回)大会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2014-09-24 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] キャビテーションピーニングを施したTi-29Nb-13Ta-4.6Zr合金製脊椎固定器具の耐久性2014

    • Author(s)
      仲井正昭, 新家光雄, 成田健吾, 趙研, 髙桑脩, 祖山均
    • Organizer
      日本金属学会2014年秋期(第155回)大会および日本鉄鋼協会第168回秋季講演大会(共同セッション)
    • Place of Presentation
      名古屋大学
    • Year and Date
      2014-09-24 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 表面硬化処理を施した生体用β型チタン合金製脊椎固定器具の圧縮疲労強度2014

    • Author(s)
      成田健吾, 新家光雄, 仲井正昭, 蘇亜拉図, 祖山均, 髙桑脩
    • Organizer
      日本機械学会2014年度年次大会
    • Place of Presentation
      東京電機大学
    • Year and Date
      2014-09-07 – 2014-09-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] Deformation-induced phase transformations in β-type biomedical titanium alloys2014

    • Author(s)
      C.J. Boehlert, H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      International Conference on Martensitic Transformations 2014 (ICOMAT-2014)
    • Place of Presentation
      Bilbao (Spain)
    • Year and Date
      2014-07-06 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Endurance of low-modulus beta-type titanium alloys for spinal fixation rods2014

    • Author(s)
      M. Niinomi, M. Nakai, J. Hieda, K. Cho and K. Narita
    • Organizer
      TMS2014 143rd Annual Meeting & Exhibition
    • Place of Presentation
      San Diego, California, USA
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 金属材料の力学的生体機能化2014

    • Author(s)
      新家光雄, 仲井正昭
    • Organizer
      日本金属学会2014年春期(第154回)大会
    • Place of Presentation
      東京工業大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Ti-29Nb-13Ta-4.6Zr合金の弾性率自己調整機能化2014

    • Author(s)
      仲井正昭, 新家光雄, 稗田純子, 趙研, 成田健吾, 李強
    • Organizer
      日本金属学会2014年春期(第154回)大会
    • Place of Presentation
      東京工業大学
    • Related Report
      2013 Research-status Report
  • [Presentation] H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho Changeable Young's modulus with twinning-induced plasticity in β-type titanium alloys for spinal fixture2014

    • Author(s)
      H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      日本金属学会2014年春期(第154回)大会
    • Place of Presentation
      東京工業大学
    • Related Report
      2013 Research-status Report
  • [Presentation] Development of changeable Young's modulus with good mechanical properties in β-type Ti-Cr-O alloys2013

    • Author(s)
      K. Cho, M. Niinomi, M. Nakai, J. Hieda and H.H. Liu
    • Organizer
      2nd International Congress on Advanced Materials (AM2013)
    • Place of Presentation
      Zhenjiang, China
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Mechanical properties of Ti-12Cr alloy with self-tunable Young's modulus for use in spinal fixation devices2013

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda and K. Cho
    • Organizer
      The 8th Pacific Rim International Conference on Advanced Materials and Processing (PRICM 8)
    • Place of Presentation
      Waikoloa, Hawaii, USA
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Deformation induced changeable Young's modulus in ternary Ti-Cr-O alloys for spinal fixation applications2013

    • Author(s)
      H.H Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      The 8th Pacific Rim International Conference on Advanced Materials and Processing (PRICM 8)
    • Place of Presentation
      Waikoloa, Hawaii, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Development of Ti-Zr based alloys with changeable Young's modulus for spinal fixation applications2013

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda, K. Cho, K. Narita and X.L. Zhao
    • Organizer
      XII Brazilian MRS Meeting
    • Place of Presentation
      Campos de Jordao, Brazil
    • Related Report
      2013 Research-status Report
  • [Presentation] Optimization of Cr and O contents in beta-type Ti-Cr-O alloys for obtaining both larger changeable Young's modulus during deformation and higher strength for use in spinal fixation applications2013

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda, K. Cho, K. Narita and H.H. Liu
    • Organizer
      Materials Science & Technology 2013 Conference & Exhibition (MS&T'13)
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2013 Research-status Report
  • [Presentation] Optimization of Mo content in beta-type Ti-Mo alloys for obtaining larger changeable Young's modulus during deformation for use in spinal fixation applications2013

    • Author(s)
      M. Nakai, M. Niinomi, J. Hieda, K. Cho, K. Narita and X.F. Zhao
    • Organizer
      THERMEC'2013
    • Place of Presentation
      Las Vegas, USA
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Enhancement of mechanical biocompatibility of titanium alloys for load bearing implant devices with relation to elastic modulus2013

    • Author(s)
      M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      International Symposium on EcoTopia Science'13 (ISETS'13)
    • Place of Presentation
      Nagoya, Japan
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 応力誘起ω相変態を利用した脊椎固定器具用チタン合金の機能化2013

    • Author(s)
      仲井正昭, 新家光雄, 成田健吾, 稗田純子, 趙研
    • Organizer
      粉体粉末冶金協会平成25年度春季大会(第111回講演大会)
    • Place of Presentation
      早稲田大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 脊椎固定用Ti-12Cr合金ロッドの曲げ特性2013

    • Author(s)
      仲井正昭, 新家光雄, 成田健吾, 稗田純子, 趙研, 劉恢弘
    • Organizer
      日本金属学会2013年秋期(第153回)大会
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Research-status Report
  • [Presentation] Influence of oxygen on deformation-induced changeable Young's modulus in β-type Ti-10Cr alloy2013

    • Author(s)
      H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      日本金属学会2013年秋期(第153回)大会および日本鉄鋼協会第166回秋季講演大会(共同セッション)
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 弾性率自己調整Ti-Mo合金のミクロ組織と力学的特性2013

    • Author(s)
      仲井正昭, 新家光雄, 稗田純子, 趙研, 成田健吾, 趙幸鋒
    • Organizer
      軽金属学会第125回秋期大会
    • Place of Presentation
      横浜国立大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 性率自己調整金属製脊椎固定ロッドの曲げ特性2013

    • Author(s)
      仲井正昭, 新家光雄, 成田健吾, 稗田純子, 趙研, 劉恢弘
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2013 Research-status Report
  • [Presentation] Effect of oxygen on changeable Young's modulus in β-type Ti-10Cr-O alloys for spinal fixture2013

    • Author(s)
      H.H. Liu, M. Niinomi, M. Nakai, J. Hieda and K. Cho
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2013 Research-status Report
  • [Presentation] 次世代医療用チタン合金の開発と脊椎固定器具への応用

    • Author(s)
      仲井正昭, 成田健吾, 新家光雄
    • Organizer
      第1回東北大学メディカルサイエンス・シンポジウム
    • Place of Presentation
      ホテルメトロポリタン仙台
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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