light confinement in plasmonic nanocavities for use as biosensor

• Project/Area Number: 25630019
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Production engineering/Processing studies
• Research Institution: The University of Tokyo
• Principal Investigator: DELAUNAY Jean-Jacques 東京大学, 工学(系)研究科(研究院), 准教授 (80376516)
• Co-Investigator(Kenkyū-buntansha): 田畑 仁 東京大学, 大学院工学系研究科, 准教授 (00263319) ; 藤川 茂紀 九州大学, カーボンニュートラル・エネルギー国際研究所, 准教授 (60333332) ; 前田 悦男 東京大学, 大学院工学系研究科, 助教 (60644599)
• Co-Investigator(Renkei-kenkyūsha): 岡本 美孝 千葉大学, 医学研究科, 教授 (40169157)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: メタマテリアル・表面プラズモン / ナノマイクロ加工 / マタマテリアル・表面プラズモン

Outline of Final Research Achievements

The purpose of the research project is to demonstrate a small-size and low-cost sensor for the early diagnosis of diseases. A very sensitive detection technique of biomarkers is being developed using confined surface plasmons in nano-cavities operating on small sample volumes. Perfect light confinement in nano-cavities is possible when high-aspect-ratio U-shaped cavities are used to couple the cavity ridge hot spots with the scalable U-cavity resonances. Under the condition of coupled resonance, light is fully trapped in intense optical vortices and confined on the extended U-shaped cavity surfaces. This strong resonance generates sensitive reflectance dips. The light confinement in the nano-cavity is realized for a finite number of adjacent nano-cavities, so small sample volumes can be used. The reported perfect light confinement in the nano-cavities observed as a strong and sharp resonance is used in biochemical marker detection in a protein-ligand scheme.

Research Products

• [Journal Article] Light trapping in finite arrays of metallic U-shaped cavities for sensing with high figure of merits (2014)
  • Author(s): Y.-L. Ho, Y. Lee, and J.-J. Delaunay
  • Journal Title: IEEE Photonics Technology Letters Volume: 26 Issue: 16 Pages: 1645-1648
  • DOI: 10.1109/lpt.2014.2329709
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Independent light-trapping cavity for ultra-sensitive plasmonic sensing (2014)
  • Author(s): Y.-L. Ho, L.-C. Huang, E. Lebrasseur, Y. Mita, and J.-J. Delaunay
  • Journal Title: Applied Physics Letters Volume: 105 Issue: 6 Pages: 061112-061112
  • DOI: 10.1063/1.4893275
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Plasmonic hybrid cavity-channel structure for tunable narrow-band optical absorption (2014)
  • Author(s): Y.-L. Ho, G. Lerondel, and J.-J. Delaunay
  • Journal Title: IEEE Photonics Technology Letters Volume: 26 Issue: 19 Pages: 1979-1982
  • DOI: 10.1109/lpt.2014.2344011
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] High sensitivity refractive index sensing with strong light confinement in high-aspect-ratio U-cavity arrays (2014)
  • Author(s): Yaerim Lee, Etsuo Maeda, Ya-Lun Ho, Shigenori Fujikawa, and Jean-Jacques Delaunay
  • Journal Title: Sensors and Actuators B Volume: 202 Pages: 137-143
  • DOI: 10.1016/j.snb.2014.05.033
  • Peer Reviewed
• [Journal Article] Effective light concentration in gold short nanosphere chain on platinum mirror for surface-enhanced Raman scattering (2014)
  • Author(s): Yaerim Lee, Minoru Abasaki, Alejandro Protela, and Jean-Jacques Delaunay
  • Journal Title: Applied Physics Letters Volume: 105 Issue: 12 Pages: 121114-121114
  • DOI: 10.1063/1.4896688
  • Peer Reviewed
• [Journal Article] Hollow plasmonic U-cavities with high-aspect-ratio nanofins sustaining strong optical vortices for light trapping and sensing (2014)
  • Author(s): Y.-L. Ho, A. Portela, Y. Lee, E. Maeda, H. Tabata, and J.-J. Delaunay
  • Journal Title: Advanced Optical Materials Volume: 2 Issue: 6 Pages: 522-528
  • DOI: 10.1002/adom.201400145
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Plasmon focusing in short gold sphere nanochains for surface enhanced Raman scattering (2013)
  • Author(s): P. Delange, Y. Ho, J.-J. Delaunay
  • Journal Title: Applied Optics Volume: 52 Issue: 36 Pages: 8809-8816
  • DOI: 10.1364/ao.52.008809
  • Peer Reviewed
• [Presentation] High-aspect-ratio plasmonic U-shaped nano-cavity with high sensitivity and figure of merit (2014)
  • Author(s): Y.-L. Ho, Y. Lee, E. Maeda, and J.-J. Delaunay
  • Organizer: Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS)
  • Place of Presentation: Honolulu, USA
  • Year and Date: 2014-04-13 – 2014-04-16
• [Presentation] Localized Surface Plasmons Coupled in U-Shaped Nano-Cavity with High Sensitivity (2013)
  • Author(s): Y.-L. Ho, Y. Lee, E. Maeda, JJ Delaunay
  • Organizer: 2013 conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR)
  • Place of Presentation: Kyoto International Conference Center
• [Presentation] Localized surface plasmons coupled to U-shaped cavity for high sensitivity bio-sensing applications (2013)
  • Author(s): J.-J. Delaunay, Y.-L. Ho, Y. Lee, E. Maeda
  • Organizer: 15th International Symposium on Olfaction and Electronic Nose
  • Place of Presentation: Daegu, Korea
• [Remarks] Plasmonics in nano-cavities for sensing
  • URL: http://scale.t.u-tokyo.ac.jp/research/index.html
• [Remarks] Plasmonics in nano-cavities for sensing
  • URL: http://scale.t.u-tokyo.ac.jp/research/index.html
• [Patent(Industrial Property Rights)] 光学素子 (2014)
  • Inventor(s): Y-L Ho, JJ Delaunay
  • Industrial Property Rights Holder: Y-L Ho, JJ Delaunay
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2014-015066
  • Filing Date: 2014-01-30