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Study on micropump made of amphiphilic molecules operating under a pH gradient

Research Project

Project/Area Number 25630351
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Properties in chemical engineering process/Transfer operation/Unit operation
Research InstitutionDoshisha University

Principal Investigator

Shioi Akihisa  同志社大学, 理工学部, 教授 (00154162)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords分子集合体 / pH勾配 / 化学走性 / 化学エネルギー / ベシクル / 自律運動 / 非線形振動 / オレイン酸
Outline of Final Research Achievements

Biological cell exhibits self-motility by chemical reactions with the surrounding chemicals. In this study, the amphiphilic molecular assemblies, that resembles biological cell, are exposed to a pH change. The chemical reactions cause the self-motion that induces convection around the molecular assembly. This is a molecular assembly pump that operates in micro-space. Recently, chemical systems with very small scale have attracted much attention for chemical analysis and synthesis. Numerous channels with micrometer scale are embedded in the small system. However, the micropumps that operates in the micro system have not fully been studied. In this study, we have designed a micropump made from amphiphilic molecules that operates by chemical reaction with the surrounding proton or hydroxide ion.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (17 results)

All 2016 2015 2014 2013

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (12 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Book (1 results)

  • [Journal Article] A molecular assembly that crawls on a solid substrate with a metabolic-like process2016

    • Author(s)
      Masato Nakada, Yukihiro Fujikami, Masaharu Kawaguchi, Daigo Yamamoto and Akihisa Shioi
    • Journal Title

      Molecular Systems Design & Engineering

      Volume: 1 Issue: 2 Pages: 1-8

    • DOI

      10.1039/c5me00012b

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Chemotactic Amoeboid-Like Shape Change of a Vesicle under a pH Gradient2015

    • Author(s)
      Erika Nawa, Daigo Yamamoto, Akihisa Shioi
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: 88 Issue: 11 Pages: 1536-1544

    • DOI

      10.1246/bcsj.20150190

    • NAID

      130005108572

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Reversible transformation of an acid/soap vesicle by glucose oxidation2015

    • Author(s)
      Erika Nawa, Daichi Sakashita, Kentaro Owaki, Daigo Yamamoto, Akihisa Shioi
    • Journal Title

      Colloid and Interface Science Communications

      Volume: 8 Pages: 10-13

    • DOI

      10.1016/j.colcom.2016.01.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rhythmic Shape Change of a Vesicle under a pH Gradient2013

    • Author(s)
      Erika Nawa, Yasuyoshi Nishigaki, Daigo Yamamoto and Akihisa Shioi
    • Journal Title

      Soft Matter

      Volume: 9 Issue: 32 Pages: 7832-7842

    • DOI

      10.1039/c3sm51100f

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] pH 変化を生成・利用して運動するベシクル2016

    • Author(s)
      名和愛利香,山本大吾,塩井章久
    • Organizer
      日本化学会 第96春季年会
    • Place of Presentation
      同志社大学(京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] グルコースの分解反応を利用したベシクルの自律運動2016

    • Author(s)
      名和 愛利香,山本 大吾,塩井 章久
    • Organizer
      化学工学会第81年会
    • Place of Presentation
      関西大学(吹田市)
    • Year and Date
      2016-03-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] Biomimetic Shape Change of a Vesicle under a pH Gradient2015

    • Author(s)
      Erika Nawa, Daigo Yamamoto, Akihisa Shioi
    • Organizer
      6th Asian Conference on Colloid and Interface Science (ACCIS 2015)
    • Place of Presentation
      アルカスSASEBO(佐世保市)
    • Year and Date
      2015-11-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] pH勾配下におけるベシクルの移動運動および破裂現象2015

    • Author(s)
      関 麻里,山本 大吾,塩井 章久
    • Organizer
      第25回 非線形反応と協同現象研究会
    • Place of Presentation
      旭川医科大学(旭川市)
    • Year and Date
      2015-10-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] pH勾配から仕事を得てアメーバ的変形を行うベシクルとそのメカニズムの解明2015

    • Author(s)
      名和 愛利香,山本 大吾,塩井 章久
    • Organizer
      化学工学会第80年会
    • Place of Presentation
      芝浦工業大学 豊洲キャンパス
    • Year and Date
      2015-03-19 – 2015-03-21
    • Related Report
      2014 Research-status Report
  • [Presentation] pH勾配下におけるベシクルのアメーバ的変形2014

    • Author(s)
      名和 愛利香,山本 大吾,塩井 章久
    • Organizer
      第24回非線形反応と協同現象研究会
    • Place of Presentation
      東京電機大学 東京千住キャンパス
    • Year and Date
      2014-12-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Biomimetic Self-motion of Colloid and Interface2014

    • Author(s)
      Akihisa Shioi
    • Organizer
      11th Korea-Japan Symposium on Materials and Interfaces
    • Place of Presentation
      Jeju, Korea, Jeju Grand Hotel
    • Year and Date
      2014-11-05 – 2014-11-07
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Interface-Driven Autonomous Motion - Biomimetic Power Source for Microsystems2014

    • Author(s)
      Akihisa Shioi
    • Organizer
      The 5th International Symposium of Advanced Energy Science
    • Place of Presentation
      Kyoto University, Uji campus
    • Year and Date
      2014-10-02
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] pH勾配下におけるベシクルのパーリングをともなう振動的変形2014

    • Author(s)
      名和 愛利香, 山本 大吾, 塩井 章久
    • Organizer
      第65回コロイド界面化学討論会
    • Place of Presentation
      東京理科大学 神楽坂校舎
    • Year and Date
      2014-09-10 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Vesicle Generating An Oscillatory Shape Change Under a pH Gradient2013

    • Author(s)
      Erika Nawa, Daigo Yamamoto and Akihisa Shioi
    • Organizer
      2013 AIChE Annual Meeting
    • Place of Presentation
      San Francisco
    • Related Report
      2013 Research-status Report
  • [Presentation] Design of Autonomously Moving Colloidal Objects: Systematic Motion of Vesicles, Particles and Oil/Water Interface in a Homogenous Chemical Field2013

    • Author(s)
      Akihisa Shioi
    • Organizer
      2013 AIChE Annual Meeting
    • Place of Presentation
      San Francisco
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] pH勾配を仕事に変換するベシクルの構造変化メカニズム2013

    • Author(s)
      名和 愛利香,山本大吾,塩井 章久
    • Organizer
      第64回コロイド界面化学討論会
    • Place of Presentation
      名古屋工業大学
    • Related Report
      2013 Research-status Report
  • [Book] Chemoresponsive Materials: Stimulation by Chemical and Biological Signals, Chap.172015

    • Author(s)
      Daigo Yamamoto, Erika Nawa and Akihisa Shioi
    • Total Pages
      33
    • Publisher
      The Royal Society of Chemistry
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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