| Project/Area Number |
25630367
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Catalyst/Resource chemical process
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 酸素酸化 / 触媒反応 / 高選択的反応 / 含酸素化合物 / 求核剤 / 酸化反応 / 触媒化学 |
|---|
| Outline of Final Research Achievements |
The introduction of an oxygen functional group into an organic compound using molecular oxygen as an oxidant under mild condition is a big problem in the organic synthesis. In this study, we have developed a new type selective catalytic oxidation reaction, in which molecular oxygen was used as an oxidant for re-oxidation of transition metal and the oxygen atom attached to the product compound was derived from a nucleophile.
Using PdCl2-DMA catalytic system, various alkenes with not only terminal but also internal double bond was easily and quantitatively oxidized to give ketones in comparison with the reaction using the conventional Wacker-Tsuji reaction. Furthermore, the oxygen functional group was selectively introduced to the substrate.
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