Development of switch controlling enzymatic activity triggered by electricity

• Project/Area Number: 25630381
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biofunction/Bioprocess
• Research Institution: Kobe University
• Principal Investigator: FUKUDA Hideki 神戸大学, その他部局等, その他 (30263396)
• Co-Investigator(Kenkyū-buntansha): TANAKA Tsutomu 神戸大学, 大学院工学研究科, 准教授 (90436551)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: バイオ燃料電池 / 代謝改変

Outline of Final Research Achievements

Useful compound production is one of the important issues of biorefinery. Here, we examined enzymatic properties under electrical stimuli, based on bio-fuel cells. As a model, we developed biofuel cells responded to oligosaccharides and generate electricity. In addition, enhancement of enzymatic signals could be achieved by two-stage oxidations.