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Auditory system of flies as a new model to study the short-term memory

Research Project

Project/Area Number 25640010
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Neurophysiology / General neuroscience
Research InstitutionNagoya University

Principal Investigator

Kamikouchi Azusa  名古屋大学, 理学(系)研究科(研究院), 教授 (00525264)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords聴覚 / 音識別 / 聴覚情報処理 / 聴覚記憶 / 神経回路 / 記憶 / ショウジョウバエ
Outline of Final Research Achievements

To start a high-through put analysis of the acoustic behavior of fruit flies, we developed an automatic system'ChaIN', to quantify the typical acoustic behavior of flies using machine-vision. By using this ChaIN software, we analyzed the acoustic behavior in response to sound of different patterns and found that the flies changed their response behavior immediately after the sound shift.This behavioral change was observed even in a memory mutant strain that lacks the rutabaga adenylyl cyclase gene, showing that the neural mechanism that discriminates sound patterns is independent of this gene. This project established a novel method to explore the neural mechanism how the brain discriminates different temporal pattern of acoustic stimuli.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (17 results)

All 2016 2015 2013

All Journal Article (6 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Acknowledgement Compliant: 1 results,  Open Access: 1 results) Presentation (8 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results) Book (3 results)

  • [Journal Article] Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster.2016

    • Author(s)
      Matsuo E, Seki H, Asai T, Morimoto T, Miyakawa H, Ito K, Kamikouchi A
    • Journal Title

      The Journal of comparative neurology

      Volume: 524 Issue: 6 Pages: 1099-1164

    • DOI

      10.1002/cne.23955

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Auditory system of fruit flies2015

    • Author(s)
      Ishikawa Y, Kamikouchi A
    • Journal Title

      Hearing research

      Volume: In Press Pages: 1-8

    • DOI

      10.1016/j.heares.2015.10.017

    • NAID

      120005868241

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster.2015

    • Author(s)
      Sano H, Nakamura A, Texada MJ, Truman JW, Ishimoto H, Kamikouchi A, Nibu Y, Kume K, Ida T, Kojima M
    • Journal Title

      PLoS genetics

      Volume: 11 Issue: 9 Pages: e1005481-e1005481

    • DOI

      10.1371/journal.pgen.1005481

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Selectivity and plasticity in a sound-evoked male-male interaction in Drosophila.2013

    • Author(s)
      Yoon J, Matsuo E, Yamada D, Mizuno H, Morimoto T, Miyakawa H, Kinoshita S, Ishimoto H, Kamikouchi A
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 9 Pages: e74289-e74289

    • DOI

      10.1371/journal.pone.0074289

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Auditory neuroscience in fruit flies.2013

    • Author(s)
      Kamikouchi A
    • Journal Title

      Neuroscience research

      Volume: 76 Issue: 3 Pages: 113-118

    • DOI

      10.1016/j.neures.2013.04.003

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neuronal encoding of sound, gravity, and wind in the fruit fly.2013

    • Author(s)
      Matsuo E, Kamikouchi A
    • Journal Title

      J Comp Physiol A

      Volume: 199 Issue: 4 Pages: 253-262

    • DOI

      10.1007/s00359-013-0806-x

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] The central auditory pathways of fruit flies2015

    • Author(s)
      Azusa Kamikouchi
    • Organizer
      H27年度新学術領域研究国際シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2015-11-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] E. Matsuo, H. Seki, T. Asai, T. Morimoto, H. Miyakawa, K. Ito, A. Kamikouchi2015

    • Author(s)
      E. Matsuo, H. Seki, T. Asai, T. Morimoto, H. Miyakawa, K. Ito, A. Kamikouchi
    • Organizer
      E. Matsuo, H. Seki, T. Asai, T. Morimoto, H. Miyakawa, K. Ito, A. Kamikouchi
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Auditory neural pathways in the fly brain2015

    • Author(s)
      Azusa Kamikouchi
    • Organizer
      3rd Asia-Pacific Drosophila Research Conference(APDRC)
    • Place of Presentation
      北京
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Elucidation of the response characteristics of subgroup-D sensory neurons in the fruit-fly ear2013

    • Author(s)
      Daichi Yamada, Eriko Matsuo, Azusa Kamikouchi
    • Organizer
      2nd Asia -Pacific Pacific Drosophila Research Conference (APDRC)
    • Place of Presentation
      ソウル
    • Related Report
      2013 Research-status Report
  • [Presentation] Auditory map in the central nervous system of Drosophila2013

    • Author(s)
      Eriko Matsuo, Haruyoshi Seki, Tomonori Asai, Takako Morimoto, Hiroyoshi Miyakawa, Kei Ito, Azusa Kamikouchi
    • Organizer
      2nd Asia -Pacific Pacific Drosophila Research Conference (APDRC)
    • Place of Presentation
      ソウル
    • Related Report
      2013 Research-status Report
  • [Presentation] The auditory circuit in the central nervous system of Drosophila2013

    • Author(s)
      Eriko Matsuo, Haruyoshi Seki, Tomonori Asai, Takako Morimoto, Hiroyoshi Miyakawa, Kei Ito, Azusa Kamikouchi
    • Organizer
      Neuro2013
    • Place of Presentation
      京都
    • Related Report
      2013 Research-status Report
  • [Presentation] Elucidation of the response characteristics of auditory nerve cells in the Drosophila brain2013

    • Author(s)
      Daichi Yamada, Eriko Matsuo, Azusa Kamikouchi
    • Organizer
      Neuro2013
    • Place of Presentation
      京都
    • Related Report
      2013 Research-status Report
  • [Presentation] Systematic analysis of a sound-evoked male-male interaction in Drosophila2013

    • Author(s)
      Jeonghyeon Yoon, Eriko Matsuo, Daichi Yamada, Hiroshi Mizuno, Takako Morimoto, Hiroyoshi Miyakawa, Setsuo Kinoshita, Azusa Kamikouchi
    • Organizer
      JSCPB2013
    • Place of Presentation
      姫路
    • Related Report
      2013 Research-status Report
  • [Book] 研究者が教える動物実験 第1巻―感覚― 第3章(13)音への応答行動を測る:求愛歌は効果あり?(キイロショウジョウバエ)2015

    • Author(s)
      石元広志、上川内あづさ
    • Total Pages
      210
    • Publisher
      共立出版
    • Related Report
      2015 Annual Research Report
  • [Book] 研究者が教える動物実験 第1巻―感覚― 第3章(14)重力への応答行動を測る:ショウジョウバエは上に逃げる?2015

    • Author(s)
      松尾恵倫子、上川内あづさ
    • Total Pages
      210
    • Publisher
      共立出版
    • Related Report
      2015 Annual Research Report
  • [Book] Methods in Neuroethological Research2013

    • Author(s)
      Kamikouchi A, Fiala A
    • Total Pages
      175
    • Publisher
      Springer Japan
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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