| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Both nature and nurture influence the learning process. Birdsong is a learned vocal behavior that is regulated by species-specific genetic constraints and individual hearing experience. However, how and when genetic and environmental instructions contribute to modulate vocal learning is not well known. In this study, we developed hybrid songbirds, whose parental species sing different species-specific songs. The hybrid songbirds showed the full-spectrum of variability of song features of parental species. Based on this behavioral data, we further performed next-generation sequence (RNA-seq) from two brain areas related to regulation of song patterns. Then, we found species-specific SNPS and genes which were differently regulated in the brain areas between two parental species and hybrids. We are further working on the studying the allelic imbalance of the species-specifically regulated genes.
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