Development of a high-resolution sample holder with lectin and binding protein on the thin film
| Project/Area Number |
25650057
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biophysics
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
Ogura Toshihiko 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 上級主任研究員 (70371028)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | バクテリア / ウイルス / 糖鎖 / 液中観察 / 走査電子顕微鏡 / レクチン / 細胞 / 窒化シリコン |
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| Outline of Final Research Achievements |
Cell infection of bacteria and virus is identified by the sugar chain and/or membrane proteins. Various sugar chains and biding proteins are located in the cell membrane, which is responsible for the important cell functions. Therefore, improving of its mechanism analysis will be helpful to various therapies. In this study, we developed a new observation method of bacteria and virus in water. This system allows for high-resolution imaging of various biological specimens with biding proteins and sugar chain under water condition. Our new method can be utilized for analysis of bacteria and virus with sugar chain and binding protein.
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Report
(4 results)
Research Products
(7 results)
