Comprehensive analyses from molecular to ecological and evolutionary dynamics in a minimum experimental ecosystem

• Project/Area Number: 25650147
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Ecology/Environment
• Research Institution: Osaka University
• Principal Investigator: Hosoda Kazufumi 大阪大学, 未来戦略機構, 准教授 (30515565)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 人工生態系 / 実験進化 / 分子機構 / 微生物実験 / 生化学反応 / 個体群動態 / 数理モデル / ダイナミクス / 進化動態 / 進化ダイナミクス / 微生物実験系 / 反応速度論 / 実験生態系

Outline of Final Research Achievements

For understanding ecological dynamics, it is necessary to consider not only the changes in populations and environments but also the changes in phenotypes of organisms, which are due to changes in molecular-level chemical reactions inside organisms, such as by evolution or phenotypic plasticity. In this study, we constructed an extraordinary simple experimental ecosystem with microorganisms to gain the experimental data of evolutionary, population, and biochemical-reaction dynamics. We then constructed mathematical models that could explain those experimental data. By those comprehensive analyses from molecular to ecological and evolutionary dynamics, we found important insights into ecological dynamics such as for maintenance of biological cooperation and mechanisms of biological adaptations.

Research Products

• [Int'l Joint Research] University of Glasgow(United Kingdom)
• [Journal Article] Population-reaction model and microbial experimental ecosystems for understanding hierarchical dynamics of ecosystems (2016)
  • Author(s): Kazufumi Hosoda, Soichiro Tsuda, Kohmei Kadowaki, Yutaka Nakamura, Tadashi Nakano, Kojiro Ishii
  • Journal Title: Biosystems Volume: 140 Pages: 28-34
  • DOI: 10.1016/j.biosystems.2015.12.005
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Adaptation of a Cyanobacterium to a Biochemically Rich Environment in Experimental Evolution as an Initial Step toward a Chloroplast-Like State (2014)
  • Author(s): Hosoda, K., Habuchi, M., Suzuki, S., Miyazaki, M., Takikawa, G., Sakurai, T., Kashiwagi, A., Sueyoshi, M., Matsumoto, Y., Kiuchi, A., Mori, K., Yomo, T.
  • Journal Title: Plos One Volume: 9(5) Issue: 5 Pages: e98337-e98337
  • DOI: 10.1371/journal.pone.0098337
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] 複数の微生物を混ぜると現実の多対多を教えてくれる (2016)
  • Author(s): 細田一史
  • Organizer: 第89回日本細菌学会総会
  • Place of Presentation: 大阪国際交流センター
  • Year and Date: 2016-03-23
  • Invited
• [Presentation] Synthetic ecosystems (2015)
  • Author(s): 細田一史
  • Organizer: 「細胞を創る」研究会 8.0
  • Place of Presentation: 大阪大学
  • Year and Date: 2015-11-12
  • Invited
• [Presentation] Introduction: Microbes go to work (2015)
  • Author(s): Hosoda K
  • Organizer: Gordon Research Conference (Microbial Population Biology)
  • Place of Presentation: Proctor Academy (Andover, NH)
  • Year and Date: 2015-07-19
  • Int'l Joint Research / Invited
• [Presentation] 微生物の実験室内進化をつかってコミュニティの進化を見て考える (2015)
  • Author(s): 細田一史
  • Organizer: 第８回Evo-devo青年の会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2015-06-27
  • Invited
• [Presentation] ニッチとは何か (2015)
  • Author(s): 細田一史
  • Organizer: 第62回日本生態学会大会
  • Place of Presentation: 鹿児島大学（鹿児島県鹿児島市）
  • Year and Date: 2015-03-19
  • Invited
• [Presentation] 結局その○○学で何がしたいのか (2014)
  • Author(s): 細田一史
  • Organizer: 生命情報科学若手の会・第6回年回
  • Place of Presentation: 理研CDB（兵庫県神戸市）
  • Year and Date: 2014-10-29
  • Invited
• [Presentation] 共生の進化原理とは何か？ (2014)
  • Author(s): 細田一史
  • Organizer: 第３回マトリョーシカ型生物学研究会
  • Place of Presentation: 神戸大学（兵庫県神戸市）
  • Year and Date: 2014-07-11
  • Invited
• [Presentation] 微生物実験系に「生物群集はどのように変化するのか」を聞く (2014)
  • Author(s): 細田一史
  • Organizer: 龍谷大セミナー
  • Place of Presentation: 龍谷大学（滋賀県大津市）
  • Year and Date: 2014-05-26
  • Invited
• [Presentation] 実験生態系の個体群動態に生化学反応を入れる (2013)
  • Author(s): 細田一史、浅尾晃央、鈴木真吾、四方哲也
  • Organizer: 第28回個体群生態学会大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
• [Presentation] 微生物による実験生態系の進化 (2013)
  • Author(s): 細田一史
  • Organizer: 第45回 種生物学シンポジウム
  • Place of Presentation: 大分県別府市亀の井ホテル別府店
  • Invited
• [Presentation] Evolutionary, population, and reaction dynamics of experimental ecosystems (2013)
  • Author(s): Kazufumi Hosoda, Makoto Sueyoshi, Itsuka Kumano, Masumi Habuchi, Kayo Yamamoto, Risa Takami, Yuhki Azuma, Isao Kubo, Shingo Suzuki, Tetsuya Yomo
  • Organizer: 第 51 回日本生物物理学会年会
  • Place of Presentation: 国立京都国際会館
• [Presentation] Toward a paradigm shift having fun with complex living systems (2013)
  • Author(s): Kazufumi Hosoda
  • Organizer: The 10th SOKENDAI Life Science Retreat
  • Place of Presentation: YAMAHA Resort TSUMAGOI, Shizuoka
  • Invited
• [Book] Methods in Molecular Biology (11. Transcriptome Analysis of a Microbial Coculture in which the Cell Populations are Separated by a Membrane) (2014)
  • Author(s): Kazufumi Hosoda, Naoaki Ono, Shingo Suzuki, and Tetsuya Yomo
  • Total Pages: 284
  • Publisher: Springer
• [Remarks] 大阪大学研究者総覧
  • URL: http://www.dma.jim.osaka-u.ac.jp/view?u=2939
• [Remarks] 個人的なホームページ
  • URL: http://www.geocities.jp/hosodakazufumi/index_J.html
• [Remarks] <細田 一史> 論文
  • URL: http://www.dma.jim.osaka-u.ac.jp/view?l=ja&u=2939&sm=&sl=&sp=&c=ronbn&dm=1