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Effect of hydration state of macromolecules on sol-gel transition of food macromolecules

Research Project

Project/Area Number 25660108
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Food science
Research InstitutionIshikawa Prefectural University

Principal Investigator

MIYAWAKI Osato  石川県立大学, 生物資源環境学部, 教授 (80012053)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords食品高分子 / ゾル・ゲル転移 / 水分活性 / 高分子水和 / 水素結合 / ゼラチン / タンパク質分子安定性 / タンパク質集合安定性 / タンパク質アンフォルディング / タンパク質水和 / 水溶液構造 / 高分子内水素結合 / タンパク質安定性 / 高分子間水素結合
Outline of Final Research Achievements

In the sol-gel transition of food macromolecules, the intermolecular hydrogen-bonding among macromolecules are broken down to bring about the hydration of macromolecules so that the water activity, as an index of the bulk state of water, is expected to affect the transition process strongly. From this standpoint of view, the sol-gel transition of food macromolecules, such as gelatin, was analyzed to show an important role of water activity in such phenomena. This result will provide an entirely new approach in the study of physical properties of food macromolecules.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] Effect of intermolecular interactions on water activity of multicomponent aqueous solutions.2015

    • Author(s)
      Haruka Sone, Chiaki Omote, Osato Miyawaki
    • Journal Title

      Japan Journal of Food Engineering

      Volume: 16 Pages: 55-59

    • NAID

      130005070498

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity2014

    • Author(s)
      Osato Miyawaki, Michiko Dozen, Kaede Nomura
    • Journal Title

      Biophysical Chemistry

      Volume: 185 Pages: 19-24

    • DOI

      10.1016/j.bpc.2013.10.004

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Thermodynamic analysis of protein stability in terms of water activity in aqueous solutions.2015

    • Author(s)
      Osato Miyawaki
    • Organizer
      8th Annual World Protein & Peptide Conference 2015
    • Place of Presentation
      南京国際青年会議ホテル、中華人民共和国
    • Year and Date
      2015-04-25 – 2015-04-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 水溶液中におけるゼラチンのゾル・ゲル転移における協同的水和効果の解析2015

    • Author(s)
      宮脇長人、表千晶、松平景子
    • Organizer
      日本農芸化学会2015年度大会
    • Place of Presentation
      岡山大学
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 適合溶質のタンパク質安定性に及ぼす影響に関する溶液熱力学的解析2014

    • Author(s)
      宮脇長人、道善倫子、野村楓
    • Organizer
      第50回低温生物工学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2014-06-28 – 2014-06-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] Lifetime turnover number of enzymes and its dependence on coexistence of substrate2014

    • Author(s)
      Osato Miyawaki, Tsukasa Kanazawa, Chika Maruyama, Michiko Dozen
    • Organizer
      10th International Conference onProtein Stabilisation (ProtStab2014)
    • Place of Presentation
      Stresa, Italy
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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