Exploring the evolution of Helicobacter pylori in deep-sea: a comprehensive analysis of ancestral microbes-host interactions.
| Project/Area Number |
25660146
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Aquatic bioproduction science
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| Research Institution | Kyoto University (2014-2015)
Hokkaido University (2013) |
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Principal Investigator |
Nakagawa Satoshi 京都大学, (連合)農学研究科(研究院), 准教授 (70435832)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 深海底熱水活動域 / 細胞外共生 / 環境応答 / マルチオミックス |
|---|
| Outline of Final Research Achievements |
The main objective of this study is to reveal the molecular mechanisms underlying the symbiosis between invertebrates and their epibionts in deep-sea hydrothermal vent environments. We especially have focused on the squat crab which is endemic to Japanese deep-sea hydrothermal fields (approximately 1000m in depth). The crab, on its setae, harbors sulfur-oxidizing symbionts belonging to Epsilonproteobacteria (including Helicobacter pylori) or Gammaproteobacteria. Effects of environmental fluctuations on the transcriptome and metabolome were examined. The molecular data were compared with corresponding data from host-endosymbiont symbiosis in deep-sea or host-pathogen interactions.
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Report
(4 results)
Research Products
(13 results)
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[Journal Article] Effects of Hemagglutination Activity in the Serum of a Deep-Sea Vent Endemic Crab, <i>Shinkaia Crosnieri</i>, on Non-Symbiotic and Symbiotic Bacteria2015
Author(s)
So Fujiyoshi, Hiroaki Tateno, Tomoo Watsuji, Hideyuki Yamaguchi, Daisuke Fukushima, Sayaka Mino, Makoto Sugimura, Tomoo Sawabe, Ken Takai, Shigeki Sawayama, Satoshi Nakagawa
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Journal Title
Microbes and Environments
Volume: 30
Issue: 3
Pages: 228-234
DOI
NAID
ISSN
1342-6311, 1347-4405
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Biogeography of Persephonella in deep-sea hydrothermal vents of the Western Pacific.2013
Author(s)
Mino, S., Makita, H., Toki, T., Miyazaki, J., Kato, S., Watanabe, H., Imachi, H., Watsuji, T., Nunoura, T., Kojima, S., Sawabe, T., Takai, K., and Nakagawa, S.
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Journal Title
Frontier in Extreme Microbiology
Volume: 4
Pages: 107-107
DOI
NAID
Related Report
Peer Reviewed
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