| Project/Area Number |
25660223
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
FUKUMOTO Shinya 帯広畜産大学, 原虫病研究センター, 准教授 (50376422)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ベクター / マラリア / マラリア原虫 / 変異体 |
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| Outline of Final Research Achievements |
This study aims to identify the parasite gene concerns to infectivity to insect vector using genome wide promoter trap mutagenesis system in malaria parasite, and investigate novel infection mechanism of the parasite to vector.
As a result of mutant screening, we successfully identified the gene concern to transmission between mammalian host and insect vector. Furthermore, we successfully developed the novel mutant parasite constructing method to analyze the gene function.
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