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Identification of the microRNAs for new biomarkers in bovine mastitis

Research Project

Project/Area Number 25660243
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionKagoshima University

Principal Investigator

MIURA Naoki  鹿児島大学, 共同獣医学部, 准教授 (80508036)

Co-Investigator(Kenkyū-buntansha) ANDO Takaaki  鹿児島大学, 共同獣医学部, 准教授 (40406898)
北原 豪  宮崎大学, 農学部, 助教 (90523415)
Co-Investigator(Renkei-kenkyūsha) KITAHARA Go  宮崎大学, 農学部獣医学科, 助教 (90523415)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords乳房炎 / ウシ / microRNA / バイオマーカー / 炎症 / 感染 / デジタルPCR
Outline of Final Research Achievements

Bovine mastitis is major concern in livestock animal. The primary aim of this study was to identify alternatively expressed miRNAs as biomarker in mastitis milk compare to normal milk.
In this study, total 9 microRNAs were identify as alternatively expressed microRNA in mastitis. Seven of them were increased and two of them were decreased. There is inflammation associated microRNAs which increased in mastitis milk. These microRNAs may be the new target miRNAs as biomarkers of bovine mastitis milk.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2015 2013

All Presentation (2 results)

  • [Presentation] microRNAの発現解析による乳房炎の診断マーカーの可能性2015

    • Author(s)
      三浦直樹,Lai Yu-Chang,藤川拓郎,安藤貴明,北原豪,窪田 力
    • Organizer
      平成26年度 日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      岡山コンベンションセンター―(岡山県・岡山市)
    • Year and Date
      2015-02-13 – 2015-02-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 乳房炎の診断マーカーとしてのmicroRNAの発現解析の可能性2013

    • Author(s)
      三浦直樹、前村 忠、鎌田 立、村田 望、北原豪、桃井康行
    • Organizer
      第156回日本獣医学会
    • Place of Presentation
      岐阜大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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