| Project/Area Number |
25660246
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Integrative animal science
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| Research Institution | Hokkaido University |
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Principal Investigator |
KON Yasuhiro 北海道大学, (連合)獣医学研究科, 教授 (10178402)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 十二指腸空腸曲 / 発生学 / マウス / 腸管屈曲 / 神経 / 発生 / 腸屈曲 |
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| Outline of Final Research Achievements |
The gastrointestinal flexure is common among individuals including many animal species. Their research helps us to understand digestive physiology and gastrointestinal pathology. In the present, duodenojejunal flexure (DJF) in mice were investigated as a model, summarizing the following, 1) the formation process was divided into expansion, early flexure and late flexure periods, 2) dorsal mesentery was not associated to DJF formation, and 3) some neural elements were important for DJF formation.
The author can clarify the mechanism of gastrointestinal flexure in individual animal species by using analysis of neural elements.
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