| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Both of fear memory suppression and fear conditioning facilitated memory consolidation. Active suppression of fear memory impaired retention of event memory. After sleep deprivation, fear memory was enhanced reflected in delayed recognition performances, indicating the generalization of fear conditioning to any other contextual events.
Activities of bilateral dorsolateral prefrontal cortex were enhanced associated with memory retention after nocturnal sleep, suggesting that the potential influence of sleep-dependent memory processing. Activities of bilateral inferior parietal lobe were also enhanced associated with the consolidation of fear conditioning, which may have engaged with an integration between unconditioned fear stimulus and word association memory formation. Furthermore, activation of right dorsolateral prefrontal cortex and bilateral anterior cingulate cortex was observed during the active suppression of fear memory.
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