Grant-in-Aid for Challenging Exploratory Research
Since cardiac myocytes cease to proliferate immediately after birth in mammalian hearts, cardiomyocyte death, induced by cardiovascular diseases, results in the reduction of cardiomyocytes in number, leading to cardiac dysfunction. In this context, the prevention of cardiomyocyte death is a promising therapeutic strategy against heart failure.In this study, we have revealed that immune surveillance system is involved in cardiac cell daeth in the process of cardiac remodling after myocardial infarction. It could be proposed that immunosurvaillance system is a novel therapeutic target against heart failure.
Biochem Biophys Res Commun
Clin Lung Cancer
International Journal of Cardiology
Eur J Clin Pharmacol
Int. J. Clin. Oncol.
Volume: (in press)
Attribution of KAKENHI