Development of new preventive methods for allergy and obesity using of the analysis on intestinal flora microbiome

• Project/Area Number: 25670295
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Epidemiology and preventive medicine
• Research Institution: Kanazawa University
• Principal Investigator: NAKAMURA HIROYUKI 金沢大学, 医学系, 教授 (30231476)
• Co-Investigator(Kenkyū-buntansha): KAMBAYASHI Yasuhiro 金沢大学, 医学系, 講師 (20345630) ; FUKUTOMI Yuma 独立行政法人国立病院機構(相模原病院臨床研究センター), 診断・治療薬開発研究室, 室長 (30463110) ; 人見 嘉哲 金沢大学, 医学系, 准教授 (70231545)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: アレルギー / 小児 / 腸内細菌 / 気管支喘息 / 食事 / 肥満 / マイクロバイオーム / メタゲノム

Outline of Final Research Achievements

The combination of allergic diseases such as asthma and obesity or overweight are considered to be produced by the eating habits. We have performed 3 years follow-up study on infants aged 3-5 years from 2013 and analyzed the strain of intestinal flora and metagenome. Four infants disappeared asthma and 5 did not, and 4 still showed pollinosis. We have observed the differences in the pattern of the expressions of enterobacteriaceae together with the intake of carbohydrates among the three groups. There was a correlation between the pattern of the expressions of the bidfidobacteriu and the increase in weight of infants after comparing between the infants with and without the disappearance of asthma. These results suggest that inhibiting unnecessary intake of carbohydrates, subsequently suppressing the excess of weight gain lead to the disappearance of asthma in infants.

Research Products

• [Journal Article] A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism (2016)
  • Author(s): Thao Thi Thu Nguyen , Tomomi Higashi , Yasuhiro Kambayashi , Enoch Olando Anyenda , Yoshimasa Michigami , Johsuke Hara , Masaki Fujimura , Hiromasa Tsujiguchi , Masami Kitaoka , Hiroki Asakura , Daisuke Hori , Yuri Hibino, Tadashi Konoshita and Hiroyuki Nakamura
  • Journal Title: Int. J. Environ. Res. Public Health Volume: 13 Issue: 1 Pages: 110-123
  • DOI: 10.3390/ijerph13010110
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy. (2016)
  • Author(s): Konno T, Nagata Y, Teramoto R, Fujino N, Nomura A, Tada H, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M, Hayashi K.
  • Journal Title: Am J Cardiol. Volume: 117 Issue: 3 Pages: 443-449
  • DOI: 10.1016/j.amjcard.2015.11.015
  • Peer Reviewed / Open Access
• [Journal Article] Prevalence of Chronic Pain, Especially Headache, and Relationship with Health-Related Quality of Life in Middle-Aged Japanese Residents. (2016)
  • Author(s): Mitoma J, Kitaoka M, Asakura H, Anyenda EO, Hori D, Nguyen TT, Hamagishi T, Hayashi K, Suzuki F, Shimizu Y, Tsujiguchi H, Kambayashi Y, Hibino Y, Konoshita T, Sagara T, Shibata A, Nakamura H
  • Journal Title: Health Volume: 8 Issue: 01 Pages: 116-124
  • DOI: 10.4236/health.2016.81014
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan. (2016)
  • Author(s): Kitaoka M, Mitoma J, Asakura H, Anyenda EO, Nguyen TT, Hamagishi T, Hori D, Suzuki F, Shibata A, Horii M, Tsujiguchi H, Hibino Y, Kambayashi Y, Hitomi Y, Shikura N, Nakamura H
  • Journal Title: Environ Health Prev Med. Volume: -
  • NAID: 210000000436
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Pharmacokinetics, safety and tolerability of Melissa officinalis extract which contained rosmarinic acid in healthy individuals: A randomized controlled trial. (2015)
  • Author(s): Noguchi-Shinohara M., Ono K., Hamaguchi T., Iwasa K., Nagai T., Kobayashi S., Nakamura H., Yamada M.
  • Journal Title: PLoS One Volume: 10 Issue: 5 Pages: e0126422-e0126422
  • DOI: 10.1371/journal.pone.0126422
  • Peer Reviewed / Open Access
• [Journal Article] Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging. (2015)
  • Author(s): Nagata Y, Konno T, Fujino N, Hodatsu A, Nomura A, Hayashi K, Nakamura H, Kawashiri MA, Yamagishi M.
  • Journal Title: Can J Cardiol. Volume: 31 Issue: 6 Pages: 702-708
  • DOI: 10.1016/j.cjca.2014.12.036
  • Peer Reviewed / Open Access
• [Journal Article] Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. (2015)
  • Author(s): Ooi A, Oyama T, Nakamura R, Tajiri R, Ikeda H, Fushida Y, Nakamura H, Dobashi Y.
  • Journal Title: Modern Pathology Volume: in press Issue: 6 Pages: 861-871
  • DOI: 10.1038/modpathol.2015.33
  • NAID: 120005593968
  • Peer Reviewed
• [Journal Article] A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. (2015)
  • Author(s): Makino Y, Konoshita T, Omori A, Maegawa N, Nakaya T, Ichikawa M, Yamamoto K, Wakahara S, Ishizuka T, Onoe T, Nakamura H; Genomic Disease Outcome Consortium (G-DOC) Study Investigators
  • Journal Title: PLoS One. Volume: 10(9) Issue: 9 Pages: e0137469-e0137469
  • DOI: 10.1371/journal.pone.0137469
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy. (2015)
  • Author(s): Konno T, Hayashi K, Fujino N, Oka R, Nomura A, Nagata Y, Hodatsu A, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M.
  • Journal Title: J Cardiovasc Electrophysiol. Volume: 26 Issue: 10 Pages: 1081-1087
  • DOI: 10.1111/jce.12742
  • Peer Reviewed / Open Access
• [Journal Article] Preventive effects of ramelteon on delirium: a randomized placebo-controlled trial (2014)
  • Author(s): Hatta K, Kishi Y, Wada K, Takeuchi T, Odawara T, Usui C, Nakamura H; DELIRIA-J Group
  • Journal Title: JAMA Psychiatry Volume: 71 Issue: 4 Pages: 397-403
  • DOI: 10.1001/jamapsychiatry.2013.3320
  • Peer Reviewed
• [Journal Article] Theobromine, the primary methylxanthine found in Theobroma cacao, prevents malignant glioblastoma proliferation by negatively regulating phosphodiesterase-4, extracellular signal-regulated kinase, Akt/mammalian target of rapamycin kinase, and nuclear factor-kappa B (2014)
  • Author(s): Sugimoto N, Miwa S, Hitomi Y, Nakamura H, Tsuchiya H, Yachie A
  • Journal Title: Nutr Cancer Volume: 66(3) Issue: 3 Pages: 419-23
  • DOI: 10.1080/01635581.2013.877497
  • Peer Reviewed
• [Journal Article] Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline. (2014)
  • Author(s): Noguchi-Shinohara M, Yuki S, Dohmoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M.
  • Journal Title: PLoS One Volume: 14;9(5) Issue: 5 Pages: e96013-e96013
  • DOI: 10.1371/journal.pone.0096013
  • Peer Reviewed
• [Journal Article] A novel coronary active perfusion system using a conventional intra-aortic balloon pump for off-pump coronary artery bypass grafting. (2014)
  • Author(s): Kiuchi R, Tomita S, Yamaguchi S, Nishida Y, Ohtake H, Nakamura H, Watanabe G
  • Journal Title: J Thorac Cardiovasc Surg Volume: 48(1) Issue: 1 Pages: 304-310
  • DOI: 10.1016/j.jtcvs.2013.11.049
  • Peer Reviewed
• [Journal Article] High sensitivity of late gadolinium enhancement for predicting microscopic myocardial scarring in biopsied specimens in hypertrophic cardiomyopathy. (2014)
  • Author(s): Konno T，Hayashi K，Fujino N，Nagata Y，Hodatsu A，Masuta E，Sakata K，Nakamura H，Kawashiri M，Yamagishi M.
  • Journal Title: PLoS One. Volume: 9 Issue: 7 Pages: e101465-e101465
  • DOI: 10.1371/journal.pone.0101465
  • NAID: 120006460361
  • Peer Reviewed / Open Access
• [Journal Article] Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study. (2014)
  • Author(s): Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakai S, Honda Y, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Anyenda EO, Hitomi Y, Nakamura H.
  • Journal Title: Atmospheric Environment Volume: 92 Pages: 506-513
  • DOI: 10.1016/j.atmosenv.2014.04.034
  • NAID: 120005463354
  • Peer Reviewed / Open Access
• [Journal Article] Clinical impacts of albuminuria and glomerular filtration rate on renal, cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. (2014)
  • Author(s): Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H; The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan
  • Journal Title: Clin Exp Nephrol Volume: - Issue: 4 Pages: 613-620
  • DOI: 10.1007/s10157-013-0879-4
  • NAID: 120005411654
  • Peer Reviewed
• [Journal Article] Erratum to: Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. (2014)
  • Author(s): Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H, The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan.
  • Journal Title: Clin Exp Nephrol Volume: 18(4) Issue: 4 Pages: 621-622
  • DOI: 10.1007/s10157-013-0931-4
  • Peer Reviewed
• [Journal Article] Long-term Heat Exposure Prevents Hypoxia-Induced Apoptosis in Mouse Fibroblast Cells (2014)
  • Author(s): Sugimoto N, Shido O, Matsuzaki K, Katakura M, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Nakamura H, Koizumi S, Yachie A and Umehara H
  • Journal Title: Cell biochemistry and biophysics Volume: (in press) Issue: 1 Pages: 301-7
  • DOI: 10.1007/s12013-014-9912-9
  • Peer Reviewed
• [Journal Article] Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. (2014)
  • Author(s): Fukutomi Y, Taniguchi M, Nakamura H, Akiyama K.
  • Journal Title: Allergy. Volume: 69(10) Issue: 10 Pages: 1405-1411
  • DOI: 10.1111/all.12481
  • Peer Reviewed
• [Journal Article] Exacerbation of daily cough and allergic symptpms in adult patients with chronic cough by Asian dust: A hospital-based study in Kanazawa (2014)
  • Author(s): Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakanishi S, Yoshizaki T, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Hitomi Y, and Nakamura H
  • Journal Title: Atmospheric Environment Volume: in press Pages: 537-543
  • DOI: 10.1016/j.atmosenv.2014.01.041
  • Peer Reviewed / Open Access
• [Journal Article] Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients : a prospective observational study (2014)
  • Author(s): Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, Tsuchida K, Oshima Y, Uchimura N, Akaho R, Watanabe A, Taira T, Nishimura K, Hashimoto N, Usui C, Nakamura H
  • Journal Title: Int J Geriatr Psychiatry Volume: 29(3) Issue: 3 Pages: 253-262
  • DOI: 10.1002/gps.3999
  • Peer Reviewed
• [Journal Article] Myasthenia gravis : Predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan (2014)
  • Author(s): Iwasa K, Yoshikawa H, Samuraki M, Shinohara M, Hamaguchi T, Ono K, Nakamura H, Yamada M
  • Journal Title: J Neuroimmunol Volume: 267(2014) Issue: 1-2 Pages: 97-101
  • DOI: 10.1016/j.jneuroim.2013.12.011
  • Peer Reviewed
• [Journal Article] The predictive value of a change in natural killer cell activity for delirium. (2014)
  • Author(s): Hatta K, Kishi Y, Takeuchi T, Wada K, Odawara T, Usui C, Machida Y, Nakamura H, for the DELIRIA-J Group
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 48 Pages: 26-31
  • DOI: 10.1016/j.pnpbp.2013.09.008
  • Peer Reviewed
• [Journal Article] The possibility that requiring high-dose olanzapine cannot be explained by pharmacokinetics in the treatment of acute-phase schizophrenia (2013)
  • Author(s): Hatta K, Takebayashi H, Sudo Y, Katayama S, Kasuya M, Shirai Y, Morikawa F, Nakase R, Nakamura M, Ito S, Kuga H, Nakamura M, Ohnuma T, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group
  • Journal Title: Psychiatry Res Volume: 210(2) Issue: 2 Pages: 396-401
  • DOI: 10.1016/j.psychres.2013.07.005
  • Peer Reviewed
• [Journal Article] Vulnerability to traumatic stress in fibromyalgia patients : 19 months follow-up after the Great East Japan Disaster (2013)
  • Author(s): Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K
  • Journal Title: Arthritis Research & Therapy Volume: 15(5) Issue: 5
  • DOI: 10.1186/ar4310
  • Peer Reviewed
• [Journal Article] The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale : reliability and validity (2013)
  • Author(s): Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Itoh K, Yamano Y, Nakamura H, Nakajima T, Nishioka K
  • Journal Title: Mod Rheumatol Volume: 23(5) Issue: 5 Pages: 846-850
  • DOI: 10.1007/s10165-012-0759-x
  • NAID: 10031201138
  • Peer Reviewed
• [Journal Article] Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics. (2013)
  • Author(s): Kimura H, Dobashi Y, Nojima T, Nakamura H, Yamamoto N, Tsuchiya H, Ikeda H, Sawada-Kitamura S, Oyama T, Ooi A
  • Journal Title: Int J Clin Exp Pathol Volume: 6(7) Pages: 1306-1316
  • Peer Reviewed
• [Journal Article] The Genomic Disease Outcome Consortium (G-DOC) Study Investigators : A crossover comparison of urinary albumin excretion as a new surrogate marker for cardiovascular disease among 4 types of calcium channel blockers (2011)
  • Author(s): Konoshita, T
  • Journal Title: Int.J.Cardiol. Volume: (in press) Issue: 2 Pages: 448-452
  • DOI: 10.1016/j.ijcard.2011.10.133
  • Peer Reviewed
• [Presentation] 黄砂を含む環境中化学物質の呼吸器疾患への影響に対するゼロ次予防 (2015)
  • Author(s): 中村裕之、神林康弘、東朋美
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 生活習慣および精神的健康度と健診受診行動との関連 (2015)
  • Author(s): 辻口博聖、堀大介、神林康弘、朝倉大貴、北岡政美、三苫純子、Anyenda Enoch Olando、Nguyen Thi Thu Thao、濱岸利夫、中村剛、木戸康人、能登裕幸、鈴木史彦、荒舩丈一、清水由香里、林宏一郎、日比野由利、柴田亜樹、相良多喜子、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 大気粒子状物質中PAH やPM2.5 やSO2と成人慢性咳嗽患者における咳症状との関連 (2015)
  • Author(s): Anyenda Enoch Olando、神林康弘、東朋美、Nguyen Thi Thu Thao、道上義正、原丈介、藤村政樹、辻口博聖、北岡政美、朝倉大貴、堀大介、三苫純子、中村剛、木戸康人、能登裕幸、日比野由利、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 慢性咳嗽患者における重金属と目のかゆみと咳との関連 IgE レベルによる違い (2015)
  • Author(s): Nguyen Thi Thu Thao、神林康弘、東朋美、Anyenda Enoch Olando、道上義正、原丈介、藤村政樹、辻口博聖、北岡政美、朝倉大貴、堀大介、三苫純子、中村剛、木戸康人、能登裕幸、日比野由利、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 精神的健康度と性，年代，生活習慣要因の関連－金沢市一般住民の横断調査 (2015)
  • Author(s): 堀大介、辻口博聖、神林康弘、濱岸利夫、北岡政美、三苫純子、朝倉大貴、鈴木史彦、Anyenda Enoch Olando、Nguyen Thi Thu Thao、中村 剛、木戸康人、能登裕幸、荒舩丈一、清水由香里、林宏一郎、日比野由利、柴田亜樹、相良多喜子、笹原信一朗、松崎一葉、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 地域における歯科医療受診者への栄養・食生活支援に関する研究 (2015)
  • Author(s): 三浦千佳、木戸康人、大滝直人、西村優希、林宏一、柴田亜樹、逸見眞理子、大西孝司、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 管理栄養士養成における歯科口腔保健分野教育の課題- 管理栄養士養成課程学生調査結果からみた一考察 - (2015)
  • Author(s): 柴田亜樹、三浦千佳、木戸康人、大滝直人、西村優希、林宏一、逸見眞理子、大西孝司、中村裕之
  • Organizer: 第13回日本予防医学会学術総会
  • Place of Presentation: フレンドパーク石川（石川県）
  • Year and Date: 2015-06-20
• [Presentation] 成人喘息のクラスター解析の現状と展望－厚生労働科学研究（大田班）の知見を含めて－ (2015)
  • Author(s): 長瀬洋之、釣木澤尚実、岩永賢司、田中明彦、谷田貝洋平、斎藤純平、鈴川真穂、東元一晃、井上博雅、棟方充、檜澤伸之、東田有智、秋山一男、出原賢治、中村裕之、大田健
  • Organizer: 第64回日本アレルギー学会学術大会
  • Place of Presentation: グランドプリンスホテル新高輪 国際館パミール（東京）
  • Year and Date: 2015-05-26
• [Presentation] 地域における食育と歯科口腔保健活動のあり方に関する一考察－兵庫県内2市の活動推進手法の比較分析－ (2014)
  • Author(s): 三浦千佳、木戸康人、大滝直人、林宏一、柴田亜樹、大西孝司、中村裕之
  • Organizer: 第12回日本予防医学会学術総会
  • Place of Presentation: 日本科学未来館（東京）
  • Year and Date: 2014-06-28 – 2014-06-30
• [Presentation] マクロ環境の話題（０次予防の取り組み例）～黄砂を含む環境中化学物質によるアレルギー疾患のゼロ次予防～ (2014)
  • Author(s): 中村裕之、東朋美
  • Organizer: 第12回日本予防医学会学術総会
  • Place of Presentation: 日本科学未来館（東京）
  • Year and Date: 2014-06-28 – 2014-06-29
  • Invited
• [Presentation] 黄砂と慢性咳嗽に関する臨床疫学 (2014)
  • Author(s): 東朋美、神林康弘、藤村政樹、西條清史、早川和一、杉本伸夫、中井里史、本田靖、人見嘉哲、中村裕之
  • Organizer: 第84回日本衛生学会学術総会
  • Place of Presentation: 岡山コンベンションセンター（岡山県）
  • Year and Date: 2014-05-25 – 2014-05-27
  • Invited
• [Presentation] 志賀町健康調査における中高年者の生活習慣病と健康関連QoL(HRQoL)の関連 (2014)
  • Author(s): 北岡政美、三苫純子、朝倉大貴、人見嘉哲、辻口博聖、神林康弘、日比野由利、アニエンダ エノックオランド、和田隆志、中村裕之
  • Organizer: 第84回日本衛生学会学術総会
  • Place of Presentation: 岡山コンベンションセンター（岡山県）
  • Year and Date: 2014-05-25 – 2014-05-27
• [Presentation] 慢性疼痛とその生活の質（QOL）への影響に対する疫学研究 (2014)
  • Author(s): 三苫純子、北岡政美、朝倉大貴、Anyenda Olando、神林康弘、日比野由利、四蔵直人、人見嘉哲、和田隆志、中村裕之
  • Organizer: 第84回日本衛生学会学術総会
  • Place of Presentation: 岡山コンベンションセンター（岡山県）
  • Year and Date: 2014-05-25 – 2014-05-27
• [Presentation] 石川県珠洲市における都市労働者に対する農作業を伴うメンタルヘルス・プログラムの経済効果推計 (2013)
  • Author(s): 水野雅男、五十嵐良雄、長井敏弘、八田耕太郎、中村裕之
  • Organizer: 第11回日本予防医学会学術総会
  • Place of Presentation: 日本科学未来館（東京都）
• [Presentation] 接触性皮膚炎患者・アトピー性皮膚炎患者の汗に含まれる金属元素およびヒスタミン濃度に関する研究 (2013)
  • Author(s): 弘田量二、黒田由季、野口修平、本宮哲也、蒲生哲司、水谷千代美、梶原完爾、中村裕之、菅沼成文
  • Organizer: 第11回日本予防医学会学術総会
  • Place of Presentation: 日本科学未来館（東京都）