• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Investigation on Sleep Disordered Breathing in Down Syndrome People

Research Project

Project/Area Number 25670299
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Epidemiology and preventive medicine
Research InstitutionKyushu University

Principal Investigator

ANDO Shin-ichi  九州大学, 大学病院, 特別教員 (90575284)

Co-Investigator(Kenkyū-buntansha) NISHIZAKA Mari  九州大学, 大学病院, 学術研究員 (00448424)
CHISHAKI Akiko  九州大学, 医学(系)研究科(研究院), 教授 (60216497)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords睡眠時無呼吸症候群 / 睡眠呼吸障害 / ダウン症候群 / いびき / 睡眠体位 / 肥満
Outline of Final Research Achievements

We evaluated the degree of obesity, sleeping positon, and symptoms that might be related sleep disordered breathing (SDB) using questionnaires in 90 care-givers of Down syndrome people (DS). We found a high prevalence of abnormal sleeping positon and SDB related symptoms in this group. We also found that the SDB related symptoms were observed irrespective of obesity in DS between 6-15 years old. The abnormal sleeping positions were reported in 27% of this DS group. We speculated that this abnormal position is an instinctive defensive mechanism against SDB. Secondly, we distributed pulse oximeters to DS and found that in the DS with abnormal sleeping position had less severe decrease in saturation level. Finally, we sent out 2000 questionnaires to caregivers of DS all over Japan to evaluate the existence of SDB related symptoms, cardiac disease and sleeping position. We found a significant relationship between severe cardiac disease and SDB.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2015 2013 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (8 results)

  • [Journal Article] A nationwide cross-sectional study on congenital heart diseases and symptoms of sleep-disordered breathing among Japanese Down’s syndrome people.2015

    • Author(s)
      Sawatari H, Chishaki A, Nishizaka M, Matsuoka F, Yoshimura C, Kuroda H, Anita Rahmawati, Hashiguchi N, Miyazono M, Ono J, Ohkusa T, Ando S.
    • Journal Title

      Internal Medicine

      Volume: -

    • NAID

      130005068318

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical and Epidemiological Features of Obstructive Sleep Apnea in a Survey of Down Syndrome Subjects in Japan.2015

    • Author(s)
      Ono J, Chishaki A, Ohkusa T, Sawatari H, Nishizaka M, Ando S.
    • Journal Title

      Nursing & Health Sciences

      Volume: - Issue: 4 Pages: 420-425

    • DOI

      10.1111/nhs.12206

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Relationship between Sleep Postures and Sleep-Disordered Breathing Parameters in People with Down Syndrome in Japan.2015

    • Author(s)
      Rahmawati A, Chishaki A, Ohkusa T, Sawatari H, Hashiguchi N, Ono J, Kuroda H, Nishizaka MK, Ando S.
    • Journal Title

      Sleep and Biological Rhythms

      Volume: - Issue: 4 Pages: 323-331

    • DOI

      10.1111/sbr.12122

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] The abnormal sleep postures that are frequently observed in people with down syndrome indicated high prevalence of the sleep disordered breathing in Japanese cross-sectional studies.2013

    • Author(s)
      Sawatari H, Chishaki A, Kuroda H, Matsuoka F, Rahmawati A, Ono J, Hashiguchi N, Miyazono M, Nishizaka M, Ando S.
    • Organizer
      Sleep2013
    • Place of Presentation
      Baltimore, U.S.A
    • Related Report
      2013 Research-status Report
  • [Presentation] Cross-sectional general survey on the relationship between congenital heart diseases and sleep disordered in patients with Down syndrome.2013

    • Author(s)
      Sawatari H, Chishaki A, Nishizaka M, Matsuoka F, Kuroda H, Hashiguchi N, Rahmawati A, Ono J, Miyazono M, Ando S.
    • Organizer
      ESC Congress2013
    • Place of Presentation
      Amsterdam, NETHERLANDS
    • Related Report
      2013 Research-status Report
  • [Presentation] We need to pay special attention on sleep postures and heart diseases in Down syndrome with sleep disordered breathing.2013

    • Author(s)
      Ono J, Sawatari H, Chishaki A, Anita Rahamawati, Kuroda H, Ando S.
    • Organizer
      World Congress on Sleep Medicine
    • Place of Presentation
      Valencia, SPAIN
    • Related Report
      2013 Research-status Report
  • [Presentation] Sleep-disordered Breathing in Adults with Down syndrome: A Cross Cultural Comparison.2013

    • Author(s)
      Sawatari H, Elizabeth A Hill, Nishizaka M, Chishaki A, Renata L Riha, Ando S.
    • Organizer
      World Congress on Sleep Medicine
    • Place of Presentation
      Valencia, SPAIN
    • Related Report
      2013 Research-status Report
  • [Presentation] Unusual Sleeping Position as a Protective Effort against Nocturnal Desaturation in Down Syndrome.2013

    • Author(s)
      アニタ ラハマワティ、樗木晶子、澤渡浩之、柳井愛香、西坂麻里、橋口暢子、小野淳二、黒田裕美、宮園真美、安藤眞一
    • Organizer
      日本睡眠学会第38回定期学術集会
    • Place of Presentation
      秋田
    • Related Report
      2013 Research-status Report
  • [Presentation] 心疾患を有するダウン症者における眠気と身体的特性に関する検討2013

    • Author(s)
      小野淳二、澤渡浩之、黒田裕美、宮園真美、橋口暢子、安藤眞一、樗木晶子
    • Organizer
      第10回日本循環器看護学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] (Symposium) Multidisciplinary approach on OSAS II Sleep disordered breathing Japanese Down syndrome.

    • Author(s)
      Ando.
    • Organizer
      The 9th sleep respiration forum in Jeju
    • Place of Presentation
      Jeju, South Korea
    • Related Report
      2013 Research-status Report
  • [Presentation] ダウン症者における睡眠呼吸障害の発生に関連する要因

    • Author(s)
      小野淳二、樗木晶子、澤渡浩之、ラハマワティ アニタ、黒田裕美、宮園真美、橋口暢子、吉村力、西坂麻里、安藤眞一
    • Organizer
      第5回ISMSJ学術集会
    • Place of Presentation
      神戸
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi