Investigation on Sleep Disordered Breathing in Down Syndrome People
| Project/Area Number |
25670299
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIZAKA Mari 九州大学, 大学病院, 学術研究員 (00448424)
CHISHAKI Akiko 九州大学, 医学(系)研究科(研究院), 教授 (60216497)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 睡眠時無呼吸症候群 / 睡眠呼吸障害 / ダウン症候群 / いびき / 睡眠体位 / 肥満 |
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| Outline of Final Research Achievements |
We evaluated the degree of obesity, sleeping positon, and symptoms that might be related sleep disordered breathing (SDB) using questionnaires in 90 care-givers of Down syndrome people (DS). We found a high prevalence of abnormal sleeping positon and SDB related symptoms in this group. We also found that the SDB related symptoms were observed irrespective of obesity in DS between 6-15 years old. The abnormal sleeping positions were reported in 27% of this DS group. We speculated that this abnormal position is an instinctive defensive mechanism against SDB. Secondly, we distributed pulse oximeters to DS and found that in the DS with abnormal sleeping position had less severe decrease in saturation level. Finally, we sent out 2000 questionnaires to caregivers of DS all over Japan to evaluate the existence of SDB related symptoms, cardiac disease and sleeping position. We found a significant relationship between severe cardiac disease and SDB.
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Report
(3 results)
Research Products
(11 results)
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[Journal Article] A nationwide cross-sectional study on congenital heart diseases and symptoms of sleep-disordered breathing among Japanese Down’s syndrome people.2015
Author(s)
Sawatari H, Chishaki A, Nishizaka M, Matsuoka F, Yoshimura C, Kuroda H, Anita Rahmawati, Hashiguchi N, Miyazono M, Ono J, Ohkusa T, Ando S.
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Journal Title
Internal Medicine
Volume: -
NAID
Related Report
Peer Reviewed / Open Access
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[Presentation] The abnormal sleep postures that are frequently observed in people with down syndrome indicated high prevalence of the sleep disordered breathing in Japanese cross-sectional studies.2013
Author(s)
Sawatari H, Chishaki A, Kuroda H, Matsuoka F, Rahmawati A, Ono J, Hashiguchi N, Miyazono M, Nishizaka M, Ando S.
Organizer
Sleep2013
Place of Presentation
Baltimore, U.S.A
Related Report
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[Presentation] Cross-sectional general survey on the relationship between congenital heart diseases and sleep disordered in patients with Down syndrome.2013
Author(s)
Sawatari H, Chishaki A, Nishizaka M, Matsuoka F, Kuroda H, Hashiguchi N, Rahmawati A, Ono J, Miyazono M, Ando S.
Organizer
ESC Congress2013
Place of Presentation
Amsterdam, NETHERLANDS
Related Report
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