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Prospective cohort study on the relationship between genetic and environmental factors and perinatal depressive symptoms

Research Project

Project/Area Number 25670305
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Epidemiology and preventive medicine
Research InstitutionEhime University (2014)
Fukuoka University (2013)

Principal Investigator

MIYAKE Yoshihiro  愛媛大学, 医学(系)研究科(研究院), 教授 (50330246)

Co-Investigator(Kenkyū-buntansha) TANAKA Keiko  愛媛大学, 大学院医学系研究科, 助教 (40341432)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords出生前コーホート研究 / 栄養 / 妊娠中うつ症状 / 有症率 / 横断研究 / 魚介類 / 乳製品 / 海草 / 社会医学 / 遺伝子多型 / 疫学研究 / 環境要因 / うつ症状 / 前向きコーホート研究 / 交互作用 / 遺伝子 / 前向きコホート研究
Outline of Final Research Achievements

Using baseline data from the Kyushu Okinawa Maternal and Child Health Study, a prebirth cohort study, we investigated the relationships maternal intake and depressive symptoms during pregnancy. Study subjects were 1745 pregnant women. Depressive symptoms were defined as present when subjects had a Center for Epidemiologic Studies Depression Scale score of 16 or higher. The prevalence of depressive symptoms during pregnancy was 19.3%. Higher consumption levels of fish, eicosapentaenoic acid, docosahexaenoic acid, yogurt, calcium, seaweed, and vitamin D were significantly associated with a lower prevalence of depressive symptoms during pregnancy. On the other hand, higher intake levels of total fat and saturated fatty acids were significantly related to a higher prevalence of depressive symptoms during pregnancy.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results,  Acknowledgement Compliant: 3 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Dietary vitamin D intake and prevalence of depressive symptoms during pregnancy in Japan.2015

    • Author(s)
      Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M.
    • Journal Title

      Nutrition.

      Volume: 31 Issue: 1 Pages: 160-165

    • DOI

      10.1016/j.nut.2014.06.013

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Intake of dairy products and calcium and prevalence of depressive symptoms during pregnancy in Japan: a cross-sectional study.2015

    • Author(s)
      Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M.
    • Journal Title

      BJOG.

      Volume: 122 Issue: 3 Pages: 336-343

    • DOI

      10.1111/1471-0528.12972

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Seaweed consumption and prevalence of depressive symptoms during pregnancy in Japan: Baseline data from the Kyushu Okinawa Maternal and Child Health Study2014

    • Author(s)
      Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M.
    • Journal Title

      BMC Pregnancy Childbirth.

      Volume: 14 Issue: 1 Pages: 301-301

    • DOI

      10.1186/1471-2393-14-301

    • NAID

      120006980635

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Fish and fat intake and prevalence of depressive symptoms during pregnancy in Japan: Baseline data from the Kyushu Okinawa Maternal and Child Health Study.2013

    • Author(s)
      Miyake Y, Tanaka K, et al.
    • Journal Title

      J Psychiatr Res

      Volume: 47 Issue: 5 Pages: 572-8

    • DOI

      10.1016/j.jpsychires.2013.01.012

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Intake of dairy products and calcium and prevalence of depressive symptoms during pregnancy in Japan.2015

    • Author(s)
      三宅吉博、田中景子、大久保公美、佐々木敏、荒川雅志.
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-01-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] ビタミンD摂取と妊娠中うつ症状との関連:九州・沖縄母子保健研究.

    • Author(s)
      三宅吉博、田中景子、大久保公美、佐々木敏、荒川雅志.
    • Organizer
      第72回日本公衆衛生学会総会
    • Place of Presentation
      三重
    • Related Report
      2013 Research-status Report
  • [Remarks] 愛媛大学大学院医学系研究科疫学・予防医学講座

    • URL

      http://www.m.ehime-u.ac.jp/school/publichealth/index.php

    • Related Report
      2014 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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