Prospective cohort study on the relationship between genetic and environmental factors and perinatal depressive symptoms
| Project/Area Number |
25670305
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Ehime University (2014)
Fukuoka University (2013) |
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Principal Investigator |
MIYAKE Yoshihiro 愛媛大学, 医学(系)研究科(研究院), 教授 (50330246)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Keiko 愛媛大学, 大学院医学系研究科, 助教 (40341432)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 出生前コーホート研究 / 栄養 / 妊娠中うつ症状 / 有症率 / 横断研究 / 魚介類 / 乳製品 / 海草 / 社会医学 / 遺伝子多型 / 疫学研究 / 環境要因 / うつ症状 / 前向きコーホート研究 / 交互作用 / 遺伝子 / 前向きコホート研究 |
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| Outline of Final Research Achievements |
Using baseline data from the Kyushu Okinawa Maternal and Child Health Study, a prebirth cohort study, we investigated the relationships maternal intake and depressive symptoms during pregnancy. Study subjects were 1745 pregnant women. Depressive symptoms were defined as present when subjects had a Center for Epidemiologic Studies Depression Scale score of 16 or higher. The prevalence of depressive symptoms during pregnancy was 19.3%. Higher consumption levels of fish, eicosapentaenoic acid, docosahexaenoic acid, yogurt, calcium, seaweed, and vitamin D were significantly associated with a lower prevalence of depressive symptoms during pregnancy. On the other hand, higher intake levels of total fat and saturated fatty acids were significantly related to a higher prevalence of depressive symptoms during pregnancy.
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Report
(3 results)
Research Products
(7 results)
