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Development of new diagnostic technique using nuclear magnetic resonance spectroscopy for detection of intracranial injury from postmortem cerebrospinal fluid

Research Project

Project/Area Number 25670346
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Legal medicine
Research InstitutionNippon Medical School

Principal Investigator

HIRAKAWA KEIKO  日本医科大学, 医学部, 助教 (30165162)

Co-Investigator(Kenkyū-buntansha) KANAWAKU Yoshimasa  防衛医科大学校, 医学教育部, 助教 (80465343)
KOIKE Kaoru  京都大学, 医学(系)研究科(研究院), 教授 (10267164)
Co-Investigator(Renkei-kenkyūsha) MORIYAMA Tuyoshi  東京工芸大学, 工学部, 准教授 (80449032)
OHNO Youkichi  日本医科大学, 医学(系)研究科(研究院), 教授 (70152220)
KANETAKE Jun  防衛医科大学校, 医学教育部, 教授 (90326661)
Project Period (FY) 2013-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords法医学 / 死体髄液 / 核磁気共鳴 / 多変量解析 / データマイニング / 死因究明
Outline of Final Research Achievements

We have investigated the data processing technique using nuclear magnetic resonance spectroscopy for detection of intracranial injury from postmortem cerebrospinal fluid. Our technique may become useful to detect a variety of lesions and improve the specificity and sensibility of diagnosis, when compared with the conventional method in which cerebral hemorrhage and subarachnoid hemorrhage have been diagnosed merely by observation of cerebrospinal fluid. While our technique is not enough to diagnose intracranial injury precisely, further development of this technique may allow improvement of the accuracy of postmortem diagnosis.

Report

(2 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )

URL: 

Published: 2014-07-25   Modified: 2017-04-10  

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