Development of therapies for severe ischemic cardiomyopathy to substute heart transplantation
Project/Area Number |
25670390
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Cardiovascular medicine
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Research Institution | The University of Tokushima |
Principal Investigator |
SATA Masataka 徳島大学, ヘルスバイオサイエンス研究部, 教授 (80345214)
|
Project Period (FY) |
2013-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
|
Keywords | 動脈硬化、 / アディポサイトカイン / 脂肪組織 / 分子血管病態学 / バイパス手術 / 心移植 / 心筋症 / 脂肪移植 / 慢性炎症 / 動脈硬化 / 血行再建 |
Research Abstract |
The only effective therapy for ischemic cardiomyopathy is heart transplantation. However, only limited numbers of donors are available in Japan. Therefore, we tried to establish a new strategy to substitute heart transplantation. Histological analysis of human endarterectomy samples and epicardial fat obtained during cardiac bypass surgery revealed enhanced infiltration of inflammatory cells such as macrophages and T cells not only in vessel wall but also in perivascular adipose tissues. We also found that interaction between cell-free DNA released from adipocytes and TLR9 on macrophages plays a crucial role in chronic inflammation in adipose tissues. Based on these observations, we started to develop a new surgical strategy to treat patients with ischemic cardiomyopathy by reconstructing coronary artery with exogenous artery and subcutaneous adipose tissues.
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Report
(2 results)
Research Products
(208 results)
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[Journal Article] Effects of Telmisartan on Inflammatory Cytokines and Coronary Plaque Component as Assessed on Integrated Backscatter Intravascular Ultrasound in Hypertensive Patients2014
Author(s)
Yamaguchi K, Wakatsuki T, Soeki T, Niki T, Taketani Y, Oeduka H, Kusunose K, Ise T, Iwase T, Yamada H, Sata M.
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Journal Title
Circulation Journal
Volume: 78
Issue: 1
Pages: 240-247
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Beneficial effect of a synthetic prostacyclin agonist, ONO-1301, in rat autoimmune myocarditis model2013
Author(s)
Y. Hirata, H. Kurobe, E. Uematsu, S. Yagi, T. Soeki, H. Yamada, D. Fukuda, M. Shimabukuro, M. Nakayama, K. Matsumoto, Y. Sakai, T. Kitagawa, M. Sata
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Journal Title
Eur. J. Pharmacol.
Volume: 699
Issue: 1-3
Pages: 81-87
DOI
Related Report
Peer Reviewed
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[Journal Article] Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury2013
Author(s)
Y. Hirata, H. Kurobe, C. Nishio, K. Tanaka, D. Fukuda, E. Uematsu, S. Nishimoto, T. Soeki, N. Harada, H. Sakaue, T. Kitagawa, M. Shimabukuro, N. Nakaya, M. Sata
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Journal Title
Eur. J. Pharmacol.
Volume: 699
Issue: 1-3
Pages: 106-111
DOI
Related Report
Peer Reviewed
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[Journal Article] Constrictive Pericarditis With Intrapericardial Abscess2013
Author(s)
H, Ogasawara K, Bando S, Ise T, Niki T, Kusunose K, Ueda Y, Tomita N, Yamaguchi K, Taketani Y, Iwase T, Soeki T, Wakatsuki T, Horiguchi H, Sakashita N, Sata M
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Journal Title
Circulation Journal
Volume: 77
Issue: 3
Pages: 786-788
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed
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[Journal Article] Perivascular adipose tissue-secreted angiopoietin-like protein2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury.2013
Author(s)
Tian Z, Miyata K, Tazume H, Sakauguchi H, Kadomatsu T, Horio E, Takahashi O, Komohara Y, Araki K, Hirata Y, Tabata M, Takanashi S, Takeya M, Hao H, Shimabukuro M, Sata M, Kawasuji M, Oike Y.
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Journal Title
J Mol Cell Cardiol
Volume: 57
Pages: 1-12
DOI
Related Report
Peer Reviewed
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[Journal Article] Ectopic fat deposition and global cardiometabolic risk: New paradigm in cardiovascular medicine2013
Author(s)
Shimabukuro M, Kozuka C, Taira T, Yabiku K, Dagvasumberel M, Ishida M, Matsumoto S, Yagi Y, FukudaD, Yamakawa K, Higa M, Soeki T, Yoshida H, Masuzaki H, Sata M
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Journal Title
The Journal of Medical Investigation
Volume: 60
Issue: 1.2
Pages: 1-14
DOI
NAID
ISSN
1343-1420, 1349-6867
Related Report
Peer Reviewed
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[Journal Article] Interval from the Onset of Transmitral Flow to Annular Velocity Is a Marker of LV Filling Pressure.2013
Author(s)
Kusunose K, Yamada H, Nishio S, Tomita N, Niki T, Yamaguchi K, Taketani Y, Iwase T, Soeki T, Wakatsuki T, Sata M
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Journal Title
JACC Cardiovasc Imaging.
Volume: 6
Issue: 4
Pages: 528-530
DOI
Related Report
Peer Reviewed
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[Journal Article] Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis2013
Author(s)
M. Shimabukuro, Y. Hirata, M. Tabata, M. Dagvasumberel, H. Sato, H. Kurobe, D. Fukuda, T. Soeki, T. Kitagawa, S. Takanashi, M. Sata
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Journal Title
Arterioscler. Thromb. Vasc. Biol.
Volume: 33
Issue: 5
Pages: 1077-1084
DOI
Related Report
Peer Reviewed
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[Journal Article] Pharmacology of aldosterone and the effects of mineralocorticoid receptor blockade on cardiovascular systems2013
Author(s)
Yagi S, Akaike M, Aihara KI, Fukuda D, Ishida M, Ise T, Niki T., Sumitomo-Ueda Y, Yamaguchi K, Iwase T, Taketani Y, Yamada H, Soeki T, Wakatsuki T, Shimabukuro M, Sata M
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Journal Title
Acta Cardiol Sin
Volume: 29巻
Pages: 201-207
Related Report
Peer Reviewed
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[Journal Article] Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling2013
Author(s)
Yoshida S, Aihara KI, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama KI, Akaike M, Matsumoto M, Sata M, Walsh K, Kato S, Matsumoto T
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Journal Title
Circulation
Volume: 128巻
Pages: 60-71
Related Report
Peer Reviewed
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[Journal Article] Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling2013
Author(s)
Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Higashida M, Matsuoka Y, Yoshida Y, Hirata Y, Sakata M, Maxfield M, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.
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Journal Title
Cardiovasc Res
Volume: 99
Issue: 4
Pages: 705-715
DOI
Related Report
Peer Reviewed
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[Journal Article] Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model.2013
Author(s)
Kurobe H, Hirata Y, Matsuoka Y, Sugasawa N, Higashida M, Nakayama T, Maxfield MW, Yoshida Y, Shimabukuro M, Kitagawa T, Sata M.
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Journal Title
J Surg Res
Volume: 185
Issue: 1
Pages: 455-462
DOI
Related Report
Peer Reviewed
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[Journal Article] Ghrelin protects the heart against ischemia-induced arrhythmias by preserving connexin-43 protein2013
Author(s)
Soeki T, Niki T, Uematsu E, Bando S, Matsuura T, Kusunose K, Ise T, Ueda Y, Tomita N, Yamaguchi K, Koshiba K, Yagi S, Fukuda D, Taketani Y, Iwase T, Yamada H, Wakatsuki T, Akaike M, Shimabukuro M, Kishimoto I, Kangawa K, Sata M
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Journal Title
Heart Vessels
Volume: 28
Issue: 6
Pages: 795-801
DOI
Related Report
Peer Reviewed
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[Journal Article] Ectopic fat deposition and global cardiometabolic risk: New paradigm in cardiovascular medicine.2013
Author(s)
Shimabukuro M, Kozuka C, Taira T, Yabiku K, Dagvasumberel M, Ishida M, Matsumoto S, Yagi Y, Fukuda D, Yamakawa K, Higa M, Soeki T, Yoshida H, Masuzaki H, Sata M.
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Journal Title
J Med Invest.
Volume: 60
Pages: 1-14
NAID
Related Report
Peer Reviewed
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[Journal Article] Pharmacology of aldosterone and the effects of mineralocorticoid receptor blockade on cardiovascular systems.2013
Author(s)
Yagi S, Akaike M, Aihara KI, Fukuda D, Ishida M, Ise T, Niki T, Sumitomo-Ueda Y, Yamaguchi K, Iwase T, Taketani Y, Yamada H, Soeki T, Wakatsuki T, Shimabukuro M, Sata M.
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Journal Title
Acta Cardiol Sin.
Volume: 29
Pages: 201-207
Related Report
Peer Reviewed
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[Journal Article] Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling.2013
Author(s)
Yoshida S, Aihara KI, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama KI, Akaike M, Matsumoto M, Sata M, Walsh K, Kato S, Matsumoto T.
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Journal Title
Circulation.
Volume: 128
Pages: 60-71
Related Report
Peer Reviewed
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[Presentation] Right ventricular systolic dysfunction in patients with exercise-induced pulmonary hypertension associated with connective tissue disease.2014
Author(s)
Saijo Y, Yamada H, Hotchi J, Nishio S, Hayashi S, Bando M, Hirata Y, Amano R, Ise T, Yagi S, Yamaguchi K, Iwase T, Soeki T, Wakatsuki T, Sata M.
Organizer
ACC 2014
Place of Presentation
The Walter E.Washington Convention Center, Washington D.C, America
Related Report
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[Presentation] Relationship between Local Production of microRNA-328 and Atrial Substrate Remodeling in Atrial Fibrillation.2014
Author(s)
Soeki T, Bando S, Matsuura T, Tobiume T, Hara T, Ota R, Takashima A, Bando M, Ogasawara K, Saito Y, Ise T, Hotchi J, Kimura E, Yamaguchi K, Yagi S, Fukuda D, Iwase T, Yamada H, Wakatsuki T, Shimabukuro M, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Increased Local Production of C-type Natriuretic Peptide in Patients with Vasospastic Angina.2014
Author(s)
Matsuura T, Soeki T, Ota R, Hara T, Saito Y, Ogasawara K, Takashima A, Bando M, Bando S, Hotchi J, Kimura E, Ise T, Tobiume T, Yamaguchi K, Yagi S, Iwase T, Yamada H, Wakatsuki T, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Impact of Cardiac Rehabilitation on Oxidized Stress in Patients with Heart Failure.2014
Author(s)
Ise T, Yagi S, Iwase T, Akaike M, Takashima A, Bando M, Bando S, Matsuura T, Hotchi J, Tobiume T, Yamaguchi K, Yamada H, Soeki T, Wakatsuiki T, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Parallel Changes in Sonographic Characteristics of Carotid and Coronary Plaques.2014
Author(s)
Bando M, Yamada H, Nishio S, Hotchi J, Hayashi S, Kimura E, Ise T, Matsuura T, Tobiume T, Yamaguchi K, Yagi S, Iwase T, Soeki T, Wakatsuki T, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Differential Responses of Local Coagulation after Implantation of Biolimus-Eluting and Everolimus-Eluting Stents Compared with Sirolimus-Eluting and Bare Metal Stents.2014
Author(s)
Yamaguchi K, Wakatsuki T, Hara T, Ogasawara K, Bando M, Takashima A, Bando S, Matsuura T, Ise T, Hotchi J, Tobiume T, Yagi S, Iwase T, Yamada H, Soeki T, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Ghrelin Ameliorates the Progression of Experimental Autoimmune Myocarditis.2014
Author(s)
Bando S, Soeki T, Hara T, Takashima A, Bando M, Ogasawara K, Saito Y, Matsuura T, Hotchi J, Kimura E, Ise T, Tobiume T, Yamaguchi K, Yagi S, Iwase T, Fukuda D, Yamada H, Wakatsuki T, Shimabukuro M, Kangawa K, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Atrial Late Potentials and Atrial Substrate Remodeling in Patients with Atrial Fibrillation.2014
Author(s)
Bando S, Soeki T, Matsuura T, Tobiume T, Hara T, Takashima A, Bando M, Ogasawara K, Saito Y, Hotchi J, Kimura E, Ise T, Yamaguchi K, Yagi S, Iwase T, Fukuda D, Yamada H, Wakatsuki T, Shimabukuro M, Sata M.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Periadventitial Adipose Tissue Secreted-Angiopoietin-like Protein 2 (Angptl2) Aggravates Neointimal Hyperplasia in Endovascular Wire Injury Model.2014
Author(s)
Tian Z, Miyata K, Tadume H, Horio E, Sakaguchi H, Hao H, Tabata M, Takanashi S, Shimabukuro M, Sata M, Kawasuji M, Oike Y.
Organizer
第78回日本循環器学会学術集会
Place of Presentation
東京国際フォーラム・JPタワーホール&カンファレンス、東京都
Related Report
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[Presentation] Rivaroxaban, A Novel Oral Anticoagulant, Attenuates Plaque Progression in ApoE-Deficient Mice Through the Inhibition of Pro-Inflammatory Activation of Macrophages2013
Author(s)
Hara T, Fukuda D, Tanaka K, Higashikuni Y, Hirata Y, Ise T, Tobiume T, Yamaguchi K, Yagi S, Iwase T, Yamada H, Soeki T, Wakatsuki T, Shimabukuro M, Sata M
Organizer
AHA Scientific Sessions 2013
Place of Presentation
ダラスコンベンションセンター(Dallas, America)
Related Report
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[Presentation] Clinical Significance of Mitral L-wave in Patients with Atrial Fibrillation and Preserved Ejection Fraction.2013
Author(s)
Nakagawa M, Yamada H, Nishio S, Hayashi S, Hotchi J, Bando M, Hirata Y, Tomofuji T, Sata M.
Organizer
ASE 2013
Place of Presentation
Minneapolis Convention Center, Minneapolis, America
Related Report
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[Presentation] Echocardiographic epicardial adipose tissue thickness in anterior interventricular groove is a marker for the presence and severity of coronary artery disease.2013
Author(s)
Hirata Y, Yamada H, Nishio S, Bando M, Hayashi S, Hotchi J, Tomofuji T, Soeki T, Wakatsuki T, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Cardiospecific microRNA plasma levels are associated with coronary plaque vulnerability.2013
Author(s)
Soeki T, Yamaguchi K, Bando S, Matsuura T, Uematsu E, Iwase T, Yamada H, Wakatsuki T, Shimabukuro M, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] MicroRNA miR-378 regulates adipocytokine fate by targeting transcriptional factors in human visceral and subctaneous adipose tissue.2013
Author(s)
Ishida M, Shimabukuro M, Yagi S, Fukuda D, Soeki T, Sato H, Uematsu E, Izaki H, Kanayama H, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] MicroRNA-100 regulates a cluster of adipocytokine expression: A human biopsy study in subcutaneous and visceral adipose tissue.2013
Author(s)
Ishida M, Shimabukuro M, Yagi S, Fukuda D, Soeki T, Sato H, Uematsu E, Izaki H, Kanayama H, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Genetic ablation of TLR9 improves insulin resistance through macrophage accumulation in adipose tissue.2013
Author(s)
Nishimoto S, Fukuda D, Shimabukuro M, Matsumoto S, Ishida M, Yagi S, Soeki T, Sakaue H, Nakaya Y, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Differential responses of local coagulation after implantation of everolimus-eluting and zotarolimus-eluting stents compared with early-generation drug-eluting stents in patients with stable angina.2013
Author(s)
Yamaguchi K, Wakatsuki T, Niki T, Taketani Y, Ise T, Yagi S, Iwase T, Yamada H, Soeki T, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Visceral fat mass is associated with daily physical activity, leg skeletal muscle mass and fiber intake in healthy men.2013
Author(s)
Nishikawa K, Yagi S, Ise T, Ueda Y, Iwase T, Akaike M, Shimabukuro M, Kato S, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] The tissue characteristics of coronary plaque with microchannel structure assessed by optical coherence tomography associated with local inflammatory response.2013
Author(s)
Wakatsuki T, Yamaguchi K, Niki T, Taketani Y, Ise T, Iwase T, Yamada H, Soeki T, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Electrophysiological correlation and prognostic impact of pentraxin 3 as a local inflammatory marker in atrial fibrillation.2013
Author(s)
Soeki T, Bando S, Matsuura T, Uenmatsu E, Yamaguchi K, Iwase T, Yamada H, Wakatsuki T, Shimabukuro M, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Ghrelin ameliorates the progression of experimental autoimmune myocarditis.2013
Author(s)
Bando S, Soeki T, Uematsu E, Matsuura T, Fukuda D, Yamada H, Wakatsuki T, Shimabukuro M, Kangawa K, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Differentiation of left ventricular systolic dysfunction related to cardiac sarcoidosis and other heart diseases using contrast-enhanced cardiovascular magnetic resonance.2013
Author(s)
Iwase T, Takao T, Akaike M, Ise T, Yagi S, Yamaguchi K, Yamada H, Nishioka Y, Harada M, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Plasma Brain Natriuretic Peptide (BNP) level is elevated in patients with cancer.2013
Author(s)
Bando S, Soeki T, Matsuura T, Yagi S, Fukuda D, Yamada H, Wakatsuki T, Shimabukuro M, Kangawa K, Sata M.
Organizer
ESC Congress 2013
Place of Presentation
Amsterdam RAI, Amsterdam, Netherlands
Related Report
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[Presentation] Post-Transcriptional Regulation of Adiponectin by Micro-RNA 378 in Human Visceral and Subcutaneous Adipose Tissue.2013
Author(s)
Ishida M, Shimabukuro M, Yagi S, Fukuda D, Soeki T, Sato H, Uematsu E, Izaki H, Kanayama H, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Time-dependent Changes Of Local Vascular Response And Angiographic Peri-stent Contrast Staining Up To Five Years After Zotarolimus-eluting, Sirolimus-eluting, And Bare Metal Stent Implantation.2013
Author(s)
Yamaguchi K, Wakatsuki T, Ise T, Tobiume T, Yagi S, Iwase T, Yamada H, Soeki T, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Decreased Local Hypercoagulation after Implantation of Everolimus-Eluting and Zotarolimus-Eluting Stents Compared with Early-Generation Drug-Eluting Stents in patients with stable angina.2013
Author(s)
Yamaguchi K, Wakatsuki T, Ise T, Tobiume T, Yagi S, Iwase T, Yamada H, Soeki T, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Impact Of Indoxy1 Sulfate, A Uremic Toxin, On Non-culprit Coronary Plaque Composition Assessed By Integrated Backscatter Intravascular Ultrasound In Patients With Coronary Artery Disease.2013
Author(s)
Yamaguchi K, Soeki T, Wakatsuki T, Ise T, Tobiume T, Yagi S, Iwase T, Yamada H, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Rivaroxaban, A Novel Oral Anticoagulant, Attenuates Plaque Progression in ApoE-Deficient Mice Through the Inhibition of Pro-Inflammatory Activation of Macrophages.2013
Author(s)
Hara T, Fukuda D, Tanaka K, Higashikuni Y, Hirata Y, Ise T, Tobiume T, Yamaguchi K, Yagi S, Iwase T, Yamada H, Soeki T, Wakatsuki T, Shimabukuro M, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Noninvasively Obtained Augmentation Index is Not a Reliable Maker for Vascular Sclerosis in Elderly Subjects.2013
Author(s)
Hayashi S, Yamada H, Hotchi J, Bando M, Ise T, Yamaguchi K, Iwase T, Soeki T, Wakatsuki T, Sata M.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Macrophage-Specific Hypoxia-Inducible Factor (HIF)-1α-Deficient Mice Suppress the Vascular Remodeling and Regulate M2 Macrophage Polarization.2013
Author(s)
Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Yoshida Y, Hirata Y, Sakata M, Maxfield MW, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.
Organizer
AHA Scientific Sessions 2013
Place of Presentation
Dallas Convention Center, Dallas, America
Related Report
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[Presentation] Right ventricular dysfunction in patients with exercise-induced pulmonary hypertension associated with connective tissue disease : an assessment using tricuspid annular motion velocities.2013
Author(s)
Hotchi J, Yamada H, Nishio S, Bando M, Hayashi S, Hirata Y, Amano R, Soeki T, Wakatsuki T, Sata M.
Organizer
Euro Echo Imaging 2013
Place of Presentation
Istanbul Lutfi Kirdar Convention & Exhibition Centre, Istanbul, Turkey
Related Report
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