| Project/Area Number |
25670515
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Hirosaki University |
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Principal Investigator |
NAKAMURA Kazuhiko 弘前大学, 医学(系)研究科(研究院), 教授 (80263911)
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| Co-Investigator(Kenkyū-buntansha) |
SUGIYAMA Toshiro 浜松医科大学, 医学部, 教授 (60216348)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 児童・思春期精神医学 / PET / 発達障害 / 自閉症 / ADHD / トラウマ処理 / ドパミンD１受容体 / ドパミンD1受容体 |
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| Outline of Final Research Achievements |
We pursued PET study for adults with developmental disorder related to abuse, which shows the symptoms of ASD and ADHD. This study reveals depressed dopamine D1 receptor, which may underpin neurophysiologic mechanism of development disorder related to abuse, and which is useful in differential diagnosis of it. As treatment of a trauma for developmental disorder related to abuse, we developed a chance-EMDR which takes short period, and found the effectiveness in treatment of a trauma.
In regard to pharmacotherapy with a few dosages, we found the effectiveness in treatment of a trauma with the prescription of herbal medicine by Kandabashi. We also found the effectiveness in treatment of comorbidities with a few dosages of antipychotics.
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