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Development of a PET/Cerenkov-light hybrid imaging system

Research Project

Project/Area Number 25670529
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionNagoya University

Principal Investigator

SEIICHI Yamamoto  名古屋大学, 医学(系)研究科(研究院), 教授 (00290768)

Co-Investigator(Renkei-kenkyūsha) HATAZAWA Jun  大阪大学, 医学系研究科, 教授 (70198745)
WATABE Hiroshi  東北大学, サイクロトロンラジオアイソトープセンター, 准教授 (40280820)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
KeywordsPET / チェレンコフ光 / 同時測定 / 複合イメージング装置 / 一体型装置
Outline of Final Research Achievements

We developed and tested a PET/Cerenkov-light hybrid imaging system. The PET/Cerenkov-light hybrid imaging system consists of a dual head PET system, reflection mirror located upper side of the subject and a high sensitivity CCD camera. These systems are installed inside a black box for imaging the Cerenkov-light. The spatial resolution of the Cerenkov-light imaging system was ~200um for Na-22 point source. Using the combined PET/Cerenkov-light imaging system, we could successfully obtain fused images with simultaneously acquired images. The distributions of the images are sometimes different from each other due to the light transmission in the body of the subject in Cerenkov-light images. We conclude that the developed PET/Cerenkov-light hybrid imaging system is useful to evaluate the merit and limitation of the Cerenkov-light imaging in molecular imaging.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Development of a PET/Cerenkov-light hybrid imaging system.2014

    • Author(s)
      Yamamoto S, Hamamura F, Watabe T, Ikeda H, Kanai Y, Watabe H, Kato K, Ogata Y, Hatazawa J.
    • Journal Title

      Med Phys

      Volume: 41 Issue: 9

    • DOI

      10.1118/1.4893535

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Ultrahigh-resolution Cerenkov-light imaging system for positron radionuclides: potential applications and limitations2014

    • Author(s)
      Yamamoto S, Watabe T, Ikeda H, Kanai Y, Watabe H, Ogata Y, Kato K, Hatazawa J.
    • Journal Title

      Ann Nucl Med.

      Volume: 28 Issue: 10 Pages: 961-9

    • DOI

      10.1007/s12149-014-0892-z

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Development of a PET/Cherenkov-Light Hybrid Imaging System2014

    • Author(s)
      S. Yamamoto1, F. Hamamura, T. Watabe, H. Ikeda, Y. Kanai, H. Watabe, K. Kato, J. Hatazawa
    • Organizer
      IEEE Nuclear Science Symposium & Medical Imaging Conference
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2014-11-08 – 2014-11-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] PET/チェレンコフ光・複合イメージング装置の開発2014

    • Author(s)
      山本誠一, 濱村風香, 渡部直史, 池田隼人, 金井泰和, 渡部浩司, 加藤克彦, 畑澤順
    • Organizer
      日本分子イメージング学会
    • Place of Presentation
      大阪,千里ライフサイエンスセンター
    • Year and Date
      2014-05-22 – 2014-05-23
    • Related Report
      2014 Annual Research Report
  • [Remarks] 名古屋大学大学院医学性研究科 山本研究室 研究紹介

    • URL

      http://s-yama.net/research.html

    • Related Report
      2014 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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