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Development of a monitoring system for ventricular assist devices using an active sensing method

Research Project

Project/Area Number 25670563
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field General surgery
Research InstitutionToin University of Yokohama (2015)
National Cardiovascular Center Research Institute (2013-2014)

Principal Investigator

Ohnuma Kentaro  桐蔭横浜大学, 医用工学部, 講師 (50527992)

Co-Investigator(Renkei-kenkyūsha) TATSUMI Eisuke  独立行政法人国立循環器病研究センター, 研究所, 部長 (00216996)
SUMIKURA Hirohito  独立行政法人国立循環器病研究センター, 研究所, 特任研究員 (20433998)
TAKEWA Yoshiaki  独立行政法人国立循環器病研究センター, 研究所, 室長 (20332405)
HOMMA Akihiko  東京電機大学, 理工学部, 教授 (20287428)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords人工心臓 / モニタリング / 流量推定 / 小型駆動装置 / 能動的計測 / 心拍変動
Outline of Final Research Achievements

In this study, we sought to investigate whether a monitoring method using parameters to be provided from a ventricular assist device (VAD) driver can be used to acquire bypass flow and biological information. As a result, we improved estimate accuracy of bypass flow by using airflow in filling phase for pneumatic VAD. This monitoring system was implemented on compact pneumatic VAD driving under development. In continuous flow system, it was suggested that the parameters of the driver-side (the input current and time constant for rotational speed) was useful to estimate the state on the load-side when the driving condition was changed. The rotational speed control for a monitoring system was compatible with the adaptive VAD control in the situation of pulsatile circulation.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (22 results)

All 2015 2014 2013

All Journal Article (4 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 3 results) Presentation (18 results)

  • [Journal Article] Development of a Compact Pneumatic Drive Unit for a Wearable Total Artificial Heart System2015

    • Author(s)
      大沼健太郎, 住倉博仁, 築谷朋典, 巽 英介, 妙中義之, 武輪能明, 水野敏秀, 片野一夫, 小嶋孝一, 向林 宏, 本間章彦
    • Journal Title

      IEEJ Transactions on Electronics, Information and Systems

      Volume: 135 Issue: 11 Pages: 1376-1385

    • DOI

      10.1541/ieejeiss.135.1376

    • NAID

      130005106315

    • ISSN
      0385-4221, 1348-8155
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Development of a flow rate monitoring method for the wearable ventricular assist device driver2014

    • Author(s)
      Ohnuma K, Homma A, Sumikura H, Tsukiya T, Takewa Y, Mizuno T, Mukaibayashi H, Kojima K, Katano K, Taenaka Y, Tatsumi E
    • Journal Title

      J Artif Organs

      Volume: Published online Issue: 2 Pages: 106-113

    • DOI

      10.1007/s10047-014-0811-z

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Application of a search algorithm using stochastic behaviors to autonomous control of a ventricular assist device2014

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Tatsumi E
    • Journal Title

      conf proc ieee eng med biol soc.

      Volume: 2014 Pages: 290-293

    • DOI

      10.1109/embc.2014.6943586

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 耐久性試験装置(ラボハートNCVC)の開発とその応用例2014

    • Author(s)
      住倉博仁, 大沼健太郎, 本間章彦, 妙中義之, 武輪能明, 築谷朋典, 水野敏秀, 向林 宏, 小嶋孝一, 巽 英介
    • Journal Title

      循環器病研究の進歩

      Volume: 35 Pages: 52-59

    • Related Report
      2014 Research-status Report
  • [Presentation] 確率的手法を用いた、自律的補助人工心臓制御の左心系模擬循環経路での評価2015

    • Author(s)
      大沼健太郎,住倉博仁,本間章彦,築谷朋典,武輪能明,水野敏秀,巽 英介
    • Organizer
      日本人工臓器学会大会 (53)
    • Place of Presentation
      東京都
    • Year and Date
      2015-11-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] 確率的探索手法による自律的補助人工心臓駆動の基礎特性に関する検討2015

    • Author(s)
      大沼健太郎,住倉博仁,本間章彦,築谷朋典,武輪能明,水野敏秀,巽 英介
    • Organizer
      日本機械学会 2015年度年次大会
    • Place of Presentation
      札幌市
    • Year and Date
      2015-09-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] Proposal and evaluation of an autonomous control algorithm using stochastic method for a ventricular assist device2015

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Tatsumi E
    • Organizer
      Annual European Society for Artificial Organs Congress (42)
    • Place of Presentation
      Leuven
    • Year and Date
      2015-09-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] In-vitro evaluation of an autonomous control algorithm using stochastic method for a ventricular assist device2015

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (61)
    • Place of Presentation
      Chicago
    • Year and Date
      2015-06-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 体外設置式補助人工心臓用モニタリングシステムの開発2014

    • Author(s)
      大沼健太郎, 住倉博仁, 本間章彦, 築谷朋典, 武輪能明, 水野敏秀, 妙中義之, 片野一夫, 小嶋孝一, 向林 宏, 巽 英介
    • Organizer
      日本人工臓器学会大会
    • Place of Presentation
      札幌市
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 体外設置式補助人工心臓用小型ポータブル駆動装置の開発2014

    • Author(s)
      大沼健太郎, 住倉博仁, 本間章彦, 築谷朋典, 武輪能明, 水野敏秀, 向林 宏, 片野一夫, 小嶋孝一, 妙中義之, 巽 英介
    • Organizer
      日本人工臓器学会大会
    • Place of Presentation
      札幌市
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of a compact drive unit with high controllability for a pneumatic total artificial heart system2014

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Takewa Y, Mizuno T, Katano K, Kojima K, Mukaibayashi H, Taenaka Y, Tatsumi E.
    • Organizer
      ESAO
    • Place of Presentation
      Rome
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Research-status Report
  • [Presentation] Application of a search algorithm using stochastic behaviors to autonomous control of a ventricular assist device2014

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Tatsumi E
    • Organizer
      IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Chicago
    • Year and Date
      2014-08-26 – 2014-08-30
    • Related Report
      2014 Research-status Report
  • [Presentation] in vivo evaluation of a compact wearable pneumatic drive unit with non-circular gears for a ventricular assist device2014

    • Author(s)
      Sumikura H, Ohnuma K, Homma A, Taenaka Y, Takewa Y, Mukaibayashi H, Katano K, Kojima K, Tatsumi E
    • Organizer
      IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Chicago
    • Year and Date
      2014-08-26 – 2014-08-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Development or a compact pneumatic drive unit with a DC servo motor for a ventricular assist device2014

    • Author(s)
      Sumikura H, Ohnuma K, Homma A, Taenaka Y, Takewa Y, Tsukiya T, Mizuno T, Mukaibayashi H, Katano K, Kojima K, Fukui Y, Tatsumi E
    • Organizer
      ASAIO
    • Place of Presentation
      Washington D.C.
    • Year and Date
      2014-06-18 – 2014-06-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 空気駆動式補助人工心臓 (Nipro LVAS) 用モニタ装置の開発2014

    • Author(s)
      大沼健太郎、住倉博仁、本間章彦、築谷朋典、武輪能明、水野敏秀、妙中義之、片野一夫、舘林千尋、小嶋孝一、向林 宏、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (42)
    • Place of Presentation
      湯沢町
    • Related Report
      2013 Research-status Report
  • [Presentation] DCサーボモータを応用した収縮期比可変小型空気圧駆動装置の開発2014

    • Author(s)
      住倉博仁、大沼健太郎、本間章彦、妙中義之、武輪能明、築谷朋典、水野敏秀、片桐伸将、角田幸秀、向林 宏、片野一夫、小嶋孝一、舘林千尋、福井康弘、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (42)
    • Place of Presentation
      湯沢町
    • Related Report
      2013 Research-status Report
  • [Presentation] 空気圧駆動式人工心臓用小型駆動装置のための空気流量を利用した拍出流量モニタに関する実験的検討2013

    • Author(s)
      大沼健太郎、本間章彦、住倉博仁、築谷朋典、武輪能明、水野敏秀、向林 宏、小嶋孝一、片野一夫、妙中義之、巽 英介
    • Organizer
      日本バイオレオロジー学会年会 (36)
    • Place of Presentation
      福岡市
    • Related Report
      2013 Research-status Report
  • [Presentation] A proposal of flexible control algorithm for artificial heart based on stochastic method2013

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Akagawa E, Fukui Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (59)
    • Place of Presentation
      Chicago
    • Related Report
      2013 Research-status Report
  • [Presentation] 自律的補助人工心臓駆動のための探索的制御法の応用に関す る検討2013

    • Author(s)
      大沼健太郎、住倉博仁、本間章彦、築谷朋典、武輪能明、水野敏秀、赤川英毅、 福井康裕、巽英介
    • Organizer
      生活生命支援医療福祉工学系学会連合大会2013
    • Place of Presentation
      甲府市
    • Related Report
      2013 Research-status Report
  • [Presentation] 空気圧駆動式ウエアラブル全人工心臓システムのための小型駆動装置の開発2013

    • Author(s)
      大沼健太郎、住倉博仁、本間章彦、築谷朋典、武輪能明、水野敏秀、向林 宏、小嶋孝一、片野一夫、妙中、義之、巽 英介
    • Organizer
      日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
    • Place of Presentation
      横浜市
    • Related Report
      2013 Research-status Report
  • [Presentation] A non-invasive assessment of cardiac function during continuous-flow LVAD support by HRV analysis2013

    • Author(s)
      Kishimoto S, Kishimoto Y, Ohnuma K, Arakawa M, Date K, Takewa Y, Nishimura M, Tatsumi E
    • Organizer
      日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
    • Place of Presentation
      Yokohama
    • Related Report
      2013 Research-status Report
  • [Presentation] HRV Analysis for Estimating Cardiac Function During Continuous-Flow LVAD Assistance2013

    • Author(s)
      Kishimoto S, Kishimoto Y, Ohnuma K, Arakawa M, Date K, Takewa Y, Nishimura M, Tatsumi E
    • Organizer
      American Heart Association's Scientific Sessions 2013
    • Place of Presentation
      Dallas
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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