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Intraoperative computer-aided pathological diagnosis of lung cancer using the device for ultrarapid immunohistochemical staining method developed in our institute.

Research Project

Project/Area Number 25670605
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Respiratory surgery
Research InstitutionAkita University

Principal Investigator

MINAMIYA Yoshihiro  秋田大学, 医学(系)研究科(研究院), 教授 (30239321)

Co-Investigator(Kenkyū-buntansha) AKAGAMI Yoichi  秋田県産業技術センター, 副所長 (00373217)
NANJO Hiroshi  秋田大学, 医学部, 准教授 (70250892)
Research Collaborator KAWAGUCHI Haruma  
TERATA Kaori  
NAKAMURA Ryuta  
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords術中迅速病理診断 / 免疫組織染色 / 自動診断 / 肺癌 / 免疫染色 / 術中迅速 / 陽性コントロール / 自動病理診断
Outline of Final Research Achievements

Intraoperative pathological diagnosis is required for the surgical treatment of cancer patients. However, a shortage of pathologists is serious in Japan. The aim of this study is the establishment of the intraoperative computer-aided pathological diagnosis. We have developed a equipment to complete immunohistochemical staining within 20 minutes. We tried to develop the intraoperative computer-aided pathological diagnosis after staining the sample using this equipment. The index of the objective evaluation is required for the intraoperative computer-aided pathological diagnosis. There are two types of positive control. One is in the morphological control, is another the concentration control. The index of the target protein concentration was made of polymer of the microhydrogel containing the target protein. The morphological index was made of the cultured cells.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2015 2014

All Patent(Industrial Property Rights) (3 results)

  • [Patent(Industrial Property Rights)] 細胞内生体分子の検出に用いる標準試料及び細胞内生体分子の検出方法2015

    • Inventor(s)
      寺田かおり、南谷佳弘、川口春馬、赤上陽一、中村竜太
    • Industrial Property Rights Holder
      国立大学法人秋田大学、川口春馬、秋田県
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-019566
    • Filing Date
      2015-02-03
    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 培養細胞を用いた標準試料及びその製造方法2015

    • Inventor(s)
      南谷佳弘、赤上陽一、中村竜太
    • Industrial Property Rights Holder
      国立大学法人秋田大学、秋田県
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-021657
    • Filing Date
      2015-02-05
    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 細胞内生体分枝の検出に用いる標準試料および細胞内生体分枝の検出方法2014

    • Inventor(s)
      南谷佳弘
    • Industrial Property Rights Holder
      国立大学法人秋田大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-030808
    • Filing Date
      2014
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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