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Radiograhic quantifications of joint space narrowing by computer-based approach on rheumatoid arthritis patients

Research Project

Project/Area Number 25670630
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthopaedic surgery
Research InstitutionThe University of Tokyo

Principal Investigator

Tanaka Sakae  東京大学, 医学部附属病院, 教授 (50282661)

Co-Investigator(Kenkyū-buntansha) OKA Hiroyuki  東京大学, 医学部附属病院, 助教 (60401064)
KADONO Yuho  東京大学, 医学部附属病院, 准教授 (70401065)
YASUI Tetsuro  帝京大学, 医学部, 准教授 (30583108)
大橋 暁  東京大学, 医学部附属病院, 助教 (20466767)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords関節リウマチ / 構造学的評価 / X線画像 / 医用情報工学 / 自動解析 / 整形外科学 / リウマチ学 / 医用画像評価 / 医用画像 / 定量評価
Outline of Final Research Achievements

The study consisted of 100 patients with rheumatoid arthritis who underwent radiography at baseline and at 1-year follow-up. The joint space narrowing (JSN) on bilateral hand and foot radiographs were assessed by our computer-based method, using the Sharp/van der Heijde method as the standard of reference. Our results suggest that our computer-based method may be useful to recognize the JSN progression on radiographs of rheumatoid hands and feet.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (19 results)

All 2015 2014 2013

All Journal Article (7 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 2 results,  Open Access: 2 results) Presentation (12 results) (of which Invited: 1 results)

  • [Journal Article] The effect of cartilage degeneration on ultrasound speed in human articular cartilage2015

    • Author(s)
      Ohashi S, Ohnishi I, Oka H, Matsumoto T, Bessho M, Nakamura K, Tanaka S
    • Journal Title

      Mod Rheumatol

      Volume: 26 Issue: 3 Pages: 426-434

    • DOI

      10.3109/14397595.2015.1097012

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The impact of joint disease on the Modified Health Assessment Questionnaire scores in rheumatoid arthritis patients: class FormattedString { value: A cross-sectional study using the National Database of Rheumatic Diseases by iR-net in Japan }2015

    • Author(s)
      Ono K, Ohashi S, Oka H, Kadono Y, Yasui T, Omata Y, Nishino J, Tanaka S, Tohma S.
    • Journal Title

      Mod Rheumatol

      Volume: 26 Issue: 4 Pages: 529

    • DOI

      10.3109/14397595.2015.1106640

    • URL

      https://localhost/en/publications/c1d427dc-e410-4c48-a51f-9c28586eb10f

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Incidence of disability and its associated factors in Japanese men and women: the Longitudinal Cohorts of Motor System Organ (LOCOMO) study.2015

    • Author(s)
      Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Nishiwaki Y, Sudo A,Omori G, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K
    • Journal Title

      J Bone Miner Metab

      Volume: 未定

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Usefulness of QuickDASH in patients with cervical laminoplasty.2014

    • Author(s)
      Nakamoto H, Oshima Y, Takeshita K, Chikuda H, Ono T, Taniguchi Y, Tanaka S.
    • Journal Title

      J Orthop Sci.

      Volume: 19 Issue: 2 Pages: 218-222

    • DOI

      10.1007/s00776-013-0515-x

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Midterm Results of Resection Arthroplasty for Forefoot Deformities in Patients with Rheumatoid Arthritis and the Risk Factors Associated with Patient Dissatisfaction2014

    • Author(s)
      Matsumoto T, Kadono Y, Nishino J, Nakamura K, Tanaka S, Yasui T.
    • Journal Title

      J Foot Ankle Surg

      Volume: 53 Issue: 1 Pages: 41

    • DOI

      10.1053/j.jfas.2013.09.014

    • URL

      https://pure.teikyo.jp/en/publications/ca9acfd2-965d-4bd0-8ea6-8a88b104d76a

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study.2014

    • Author(s)
      Muraki S, Akune T, En-Yo Y, Yoshida M, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N
    • Journal Title

      Mod Rheumatol

      Volume: 24 Issue: 2 Pages: 236-42

    • DOI

      10.3109/14397595.2013.854055

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The mid-term efficacy of intra-articular hyaluronic acid injections on joint structure: A nested case-control study.2013

    • Author(s)
      Oka H, Akune T, Muraki S, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N.
    • Journal Title

      Modern Rheum

      Volume: 23 Issue: 4 Pages: 722-8

    • DOI

      10.1007/s10165-012-0725-7

    • NAID

      10031189167

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 関節リウマチにおける骨粗鬆症と骨破壊対策2015

    • Author(s)
      田中栄
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2015-07-23
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 多施設共同研究にみるセルトリズマブペゴルの有効性と安全性2015

    • Author(s)
      門野夕峰、田中栄
    • Organizer
      日本リウマチ学会総会・学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-04-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] 関節リウマチ患者におけるテリパラチド投与下の骨密度・骨強度評価2015

    • Author(s)
      大野久美子、大橋暁、門野夕峰、安井哲郎、岡敬之、田中栄
    • Organizer
      日本リウマチ学会総会・学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-04-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] Prevalence of hand osteoarthritis and associated factor -The ROAD stud2015

    • Author(s)
      児玉理恵、岡敬之、田中栄、吉村典子
    • Organizer
      日本手外科学会学術集会(英語セッション)
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] Mutual associations among diseases causing disability, such as musculoskeletal diseases, metabolic syndrome components, and mild cognitive impairment: A 3-year follow-up of the population-based cohort ROAD.2014

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T
    • Organizer
      IOF Regionals 5th Asia-Pacific Osteoporosis Meeting
    • Place of Presentation
      IOF Regionals 5th Asia-Pacific Osteoporosis Meeting, Taipei, Chinese Taipei
    • Year and Date
      2014-11-14 – 2014-11-16
    • Related Report
      2014 Research-status Report
  • [Presentation] Assessment of joint destruction at the knee in rheumatoid arthritis using semi-automated software for Magnetic resonance image analysis.2014

    • Author(s)
      Oka H, Ohashi S, Kadono Y, Yasui T, Ono K, Isawa K, Yoshimura N, Nishino J, Tanaka S
    • Organizer
      The European League Against Rheumatism (EULAR) 2014
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-06-11 – 2014-06-14
    • Related Report
      2014 Research-status Report
  • [Presentation] NinJaを用いた下肢人工関節全置換術(TKA・THA)患者の術後中期身体機能に影響を与える因子の検討2014

    • Author(s)
      大橋暁、門野夕峰、安井哲郎、正田奈緒子、伊澤一也、大野久美子、岡敬之、西野仁樹、田中栄、當間重人
    • Organizer
      第58回 日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24 – 2014-04-26
    • Related Report
      2014 Research-status Report
  • [Presentation] NinJaを用いたRA患者における各関節罹患がmHAQに及ぼす影響の検討2014

    • Author(s)
      19.大野久美子、大橋暁、岡敬之、門野夕峰、安井哲郎、伊澤一也、正田奈緒子、西野仁樹、田中栄、當間重人
    • Organizer
      第58回 日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24 – 2014-04-26
    • Related Report
      2014 Research-status Report
  • [Presentation] リウマチ性疾患の疫学 関節リウマチ患者の手指関節破壊を評価する身体機能尺度の探索2014

    • Author(s)
      安井哲郎、岡敬之、門野夕峰、大橋暁、正田奈緒子、伊澤一也、大野久美子、田中栄
    • Organizer
      第58回 日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24 – 2014-04-26
    • Related Report
      2014 Research-status Report
  • [Presentation] Higher levels of serum 25(OH)D prevents the occurrence of osteoporosis, but deteriorates knee osteoarthritis: A 3-year follow-up of the ROAD study.2013

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Nakamura K, Tanaka S, Kawaguchi H, Akune T
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society (IBMS) and the Japanese Society for Bone and Mineral Research (JSBMR)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2013 Research-status Report
  • [Presentation] Risk Factors for Multiple Falls in Japanese Men and Women: The ROAD Study.2013

    • Author(s)
      Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura, K, Oka H, Yoshimura N
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society (IBMS) and the Japanese Society for Bone and Mineral Research (JSBMR)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2013 Research-status Report
  • [Presentation] Prevalence of sarcopenia and its association with exercise habits in the elderly of Japanese population-based cohorts: The ROAD Study.2013

    • Author(s)
      Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N
    • Organizer
      IOF Regionals 4th Asia-Pacific Osteoporosis Meeting
    • Place of Presentation
      Hong Kong
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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