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Association between carcinogenesis of the cervix and HLA class II polymorphism.

Research Project

Project/Area Number 25670693
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionUniversity of Tsukuba

Principal Investigator

YOSHIKAWA HIROYUKI  筑波大学, 医学医療系, 教授 (40158415)

Co-Investigator(Kenkyū-buntansha) MAEDA Hiroo  埼玉医科大学, 医学部, 教授 (30134597)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords子宮頸がん / ヒトパピローマウイルス(HPV) / ヒト白血球型抗原(HLA) / ヒトパピローマウイルス(HPV) / ヒト白血球型抗原(HLA) / ヒトパピローマウイルス (HPV) / ヒト白血球型抗原 (HLA)
Outline of Final Research Achievements

The aim was to investigate associations between HLA class II alleles and risks of cervical cancer in a Japanese population. A cross-sectional analysis for HLA association with cervical cancer included 1253 Japanese women: normal cytology (n=341), CIN1/2 (n=591), and CIN3 or invasive cervical cancer (n=321). Furthermore, the CIN1/2 cases were prospectively monitored to analyze cumulative probability of progression to CIN3. Compared with women with normal cytology or CIN1/2, DRB1*0901 and DRB1*1302 frequencies were significantly decreased among women with CIN3/ICC (P=0.00001 and P=0.006, respectively). Based on follow-up data of 454 women with CIN1/2, the risk of progression to CIN3 within the next 10 years was significantly reduced among DRB1*1302-positive women (3.2% vs. 23.7%, P=0.03),. CONCLUSION: By using cross-sectional and prospective study designs, we demonstrated the protective effect of the DRB1*1302 allele against progression to CIN3/ICC. 965

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (72 results)

All 2015 2014 2013 2012

All Journal Article (32 results) (of which Peer Reviewed: 22 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (40 results) (of which Invited: 2 results)

  • [Journal Article] Administration of standard-dose BEP regimen (bleomycin+etoposide+cisplatin) is essential for treatment of ovarian yolk sac tumour2015

    • Author(s)
      Satoh T, Aoki Y, Kasamatsu T, Ochiai K, Takano M, Watanabe Y, Kikkawa F, Takeshima N, Hatae M, Yokota H, Saito T, Yaegashi N, Kobayashi H, Baba T, Kodama S, Saito T
    • Journal Title

      Eur J Cancer

      Volume: 51 Issue: 3 Pages: 340-51

    • DOI

      10.1016/j.ejca.2014.12.004

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased CD11b+ Gr-1+ cell population in the placenta after infection with Toxoplasma gondii.2015

    • Author(s)
      Takeshima K, Sato K, Nabekura T, Nagamune K, Hamada H, Yoshikawa H, Shibuya A, Shibuya K.
    • Journal Title

      Microbiol. immunol

      Volume: 59 Issue: 2 Pages: 95-98

    • DOI

      10.1111/1348-0421.12225

    • NAID

      120007130301

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Glucocorticoids facilitate the transcription from the human cytomegalovirus major immediate early promoter in glucocorticoid receptor- and nuclear factor-I-like protein-dependent manner.2015

    • Author(s)
      Inoue-Toyoda M, Kato K, Nagata K, Yoshikawa H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 476 Issue: 1 Pages: 9-14

    • DOI

      10.1016/j.bbrc.2015.01.091

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Pathology-oriented treatment strategy of malignant ovarian tumor in pregnant women: analysis of 41 cases in Japan.2014

    • Author(s)
      Morikawa A, Ueda K, Takahashi K, Fukunaga M, Iwashita M, Kobayashi Y, Takechi K, Umezawa S, Terauchi F, Kiguchi K, Aoki D, Nomura H, Yoshikawa H, Satoh T, Jobo T, Fujiwara H, Takei Y, Kamoi S, Terao Y, Isonishi S.
    • Journal Title

      Int J Clin Oncol.

      Volume: 19 Issue: 6 Pages: 1074-1079

    • DOI

      10.1007/s10147-014-0669-3

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Moesin overexpression is a unique biomarker of adenomyosis.2014

    • Author(s)
      Ohara R, Michikami H, Nakamura Y, Sakata A, Sakashita S, Satomi K, Shiba-Ishii A, Kano J, Yoshikawa H, Noguchi M.
    • Journal Title

      Pathol Int.

      Volume: 64 Issue: 3 Pages: 115-122

    • DOI

      10.1111/pin.12148

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical intraepithelial neoplasia and cervical infection in young Japanese women: open follow-up of a randomised clinical trial up to four years post-vaccination.2014

    • Author(s)
      Konno R, Yoshikawa H, Okutani M, Quint W, Pemmaraju S, Lin L, Struyf F.
    • Journal Title

      Hum Vaccin Immunother.

      Volume: 10 Issue: 7 Pages: 1781-1794

    • DOI

      10.4161/hv.28712

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monitoring the impact of a national HPV vaccination program in Japan (MINT study): rationale, design and methods.2014

    • Author(s)
      Matsumoto K, Yaegashi N, Iwata T, Ariyoshi K, Fujiwara K, Shiroyama Y, Usami T, Kawano Y, Horie K, Kawano K, Noda K, Yoshikawa H for MINT Study Group
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 44 Issue: 10 Pages: 1000-1003

    • DOI

      10.1093/jjco/hyu097

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 未来の医療を創る臨床試験―計画・実行の勧め―2014

    • Author(s)
      吉川裕之
    • Journal Title

      日本産婦人科学会雑誌

      Volume: 66 Pages: 1948-1957

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 卵巣癌の治療と妊孕性温存2014

    • Author(s)
      佐藤豊実、志鎌あゆみ、道上大雄、吉川裕之
    • Journal Title

      産科と婦人科

      Volume: 81 Pages: 1237-1242

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 産婦人科領域 この10年の進歩2014

    • Author(s)
      吉川裕之
    • Journal Title

      内科

      Volume: 114 Pages: 1132-1136

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 婦人科がん-子宮頸がん-2014

    • Author(s)
      吉川裕之
    • Journal Title

      最新がん薬物療法学

      Volume: 72(2) Pages: 417-424

    • Related Report
      2013 Research-status Report
  • [Journal Article] 3.婦人科腫瘍の治療「A婦人科悪性腫瘍手術の留意点」2014

    • Author(s)
      吉川裕之
    • Journal Title

      プリンシプル産科婦人科学

      Volume: - Pages: 431-431

    • Related Report
      2013 Research-status Report
  • [Journal Article] V.婦人科疾患の手術療法「1.手術療法」2014

    • Author(s)
      吉川裕之
    • Journal Title

      プリンシプル産科婦人科学

      Volume: - Pages: 734-741

    • Related Report
      2013 Research-status Report
  • [Journal Article] Human papillomavirus infection and risk for cervical cancer in Japan.2013

    • Author(s)
      Matsumoto K, Yoshikawa H
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 39(1) Issue: 1 Pages: 7-17

    • DOI

      10.1111/j.1447-0756.2012.01977.x

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Safety and efficacy of substituting nedaplatin after carboplatin hypersensitivity reactions in gynecologic malignancies.2013

    • Author(s)
      Michikami H, Minaguchi T, Ochi H, Onuki M, Okada S, Matsumoto K, Satoh T, Oki A, Yoshikawa H.
    • Journal Title

      J Obstet Gynecol Res

      Volume: 39(1) Issue: 1 Pages: 330-335

    • DOI

      10.1111/j.1447-0756.2012.01893.x

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma2013

    • Author(s)
      Abe A, Minaguchi T, Ochi H, Onuki M, Okada S, Matsumoto K, Satoh T, Oki A, Yoshikawa H
    • Journal Title

      Human Pathology

      Volume: 44(2) Issue: 2 Pages: 199-207

    • DOI

      10.1016/j.humpath.2012.05.005

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between carotenoids and outcome of cervical intraepithelial neoplasia: a prospective cohort study.2013

    • Author(s)
      Fujii T
    • Journal Title

      Int J Clin Oncol

      Volume: in press Issue: 6 Pages: 1091-101

    • DOI

      10.1007/s10147-012-0486-5

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Efficacy of quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine (GARDASIL[〇!R]) in Japanese women aged 18 to 26 years.2013

    • Author(s)
      Yoshikawa H, Ebihara K, Tanaka Y, Noda K
    • Journal Title

      Cancer Science

      Volume: 104(4) Issue: 4 Pages: 465-472

    • DOI

      10.1111/cas.12106

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Incidence of venous thromboembolism before treatment in cervical cancer and the impact of management on venous thromboembolism after commencement of treatment.2013

    • Author(s)
      Toyomi Satoh, Koji Matsumoto, Yumiko O Tanaka, Azusa Akiyama, Sari Nakao, Manabu Sakurai, Hiroyuki Ochi, Mamiko Onuki, Takeo Minaguchi, Hideyuki Sakurai, Hiroyuki Yoshikawa.
    • Journal Title

      Thrombosis Research

      Volume: 131(4) Issue: 4 Pages: e127-e132

    • DOI

      10.1016/j.thromres.2013.01.027

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical Management of Atypical Polypoid Adenomyoma of the Uterus. A Clinicopathological Review of 29 Cases2013

    • Author(s)
      Matsumoto T, Hiura M, Baba T, Ishiko O, Shiozawa T, Yaegashi N, Kobayashi H, Yoshikawa H, Kawamura N, Kaku T
    • Journal Title

      Gynecol Oncol

      Volume: 129(1) Issue: 1 Pages: 54-57

    • DOI

      10.1016/j.ygyno.2012.12.040

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diversity in size and signal intensity in multilocular cystic ovarian masses: New parameters for distinguishing metastatic from primary mucinous ovarian neoplasms.2013

    • Author(s)
      Tanaka YO, Okada S, Satoh T, Matsumoto K, Oki A, Saida T, Yoshikawa H, Minami M
    • Journal Title

      J Magn Reson Imaging.

      Volume: (in press) Issue: 4 Pages: 794-801

    • DOI

      10.1002/jmri.24058

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102).2013

    • Author(s)
      Katsumata N, Yoshikawa H, Kobayashi H, Saito T, Kuzuya K, Nakanishi T, Yasugi T, Yaegashi N, Yokota H, Kodama S , Mizunoe T, Hiura M, Kasamatsu T, Shibata T, Kamura T
    • Journal Title

      Br J Cancer.

      Volume: 108(10) Issue: 10 Pages: 1957-1963

    • DOI

      10.1038/bjc.2013.179

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Loss of PTEN expression is an independent predictor of favourable survival in endometrial carcinomas.2013

    • Author(s)
      Akiyama-Abe A, Minaguchi T, Nakamura Y, Michikami H, Shikama A, Nakao S, Sakurai M, Ochi H, Onuki M, Matsumoto K, Satoh T, Oki A, Yoshikawa H
    • Journal Title

      British Journal of Cancer

      Volume: 109 Issue: 6 Pages: 1703-1710

    • DOI

      10.1038/bjc.2013.455

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Status of treatment for the overall population of patients with stage IVb2013

    • Author(s)
      Eto T, Saito T, Shimokawa M, Hatae M, Takeshima N, Kobayashi H, Kasamatsu T, Yoshikawa H, Kamura T, Konishi I
    • Journal Title

      Gynecol Oncol.

      Volume: 131(3) Issue: 3 Pages: 574-580

    • DOI

      10.1016/j.ygyno.2013.08.036

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Surgery for endometrial cancers with suspected cervical involvement: is radical hysterectomy needed (a GOTIC study)?2013

    • Author(s)
      Takano M, Ochi H, Takei Y, Miyamoto M, Hasumi Y, Kaneta Y, Nakamura K, Kurosaki A, Satoh T, Fujiwara H, Nagao S, Furuya K, Yokota H, Ito K, Minegishi T, Yoshikawa H, Fujiwara K, Suzuki M.
    • Journal Title

      Br J Cancer

      Volume: 109(7) Issue: 7 Pages: 1760-1765

    • DOI

      10.1038/bjc.2013.521

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Therapeutic effect of dienogest on adenosarcoma arising from endometriosis: a case report2013

    • Author(s)
      Tasaka N, Matsumoto K, Satoh T, Minaguchi T, Onuki M, Ochi H, Tanaka YO, Sakata A, Noguchi M, Yoshikawa H.
    • Journal Title

      Springerplus

      Volume: 2 Issue: 1 Pages: 618-618

    • DOI

      10.1186/2193-1801-2-618

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 卵巣癌腫瘍減量手術の基本手技を学ぶ ー卵巣癌患者の予後よQOL向上を目指してー2013

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科手術

      Volume: 24 Pages: 69-75

    • Related Report
      2013 Research-status Report
  • [Journal Article] 自律神経温存が推奨される広汎子宮全摘出術の適応と手技は?2013

    • Author(s)
      佐藤豊実、吉川裕之
    • Journal Title

      EBM 婦人科疾患の治療

      Volume: - Pages: 240-245

    • Related Report
      2013 Research-status Report
  • [Journal Article] 子宮頸癌以外のHPV疾患とHPVワクチン2013

    • Author(s)
      吉川裕之
    • Journal Title

      東京都医師会雑誌

      Volume: 66(7) Pages: 36-40

    • Related Report
      2013 Research-status Report
  • [Journal Article] リスク因子を考慮した子宮体がん予防2013

    • Author(s)
      水口剛雄、吉川裕之
    • Journal Title

      臨床婦人科産科

      Volume: 67(8) Pages: 798-804

    • Related Report
      2013 Research-status Report
  • [Journal Article] 子宮頸がんの発がん機構2013

    • Author(s)
      水口剛雄、吉川裕之
    • Journal Title

      プロメテウス婦人科がん最新医療(産婦人科の実際)臨時増刊号

      Volume: 62(12)) Pages: 1624-1631

    • Related Report
      2013 Research-status Report
  • [Journal Article] Rapid genotyping of carcinogenic human papillomavirus by loop-mediated isothermal amplification using a new automated DNA test (ClinichipHPV).2012

    • Author(s)
      Satoh T, Matsumoto K, Fujii T, Sato O, Gemma N, Onuki M, Saito H, Aoki D, Hirai Y, Yoshikawa H
    • Journal Title

      J Virol Methods

      Volume: 188(1-2) Issue: 1-2 Pages: 83-93

    • DOI

      10.1016/j.jviromet.2012.10.014

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 産婦人科疾患と臨床用語2014

    • Author(s)
      吉川裕之
    • Organizer
      2014年度医師事務作業補助者指導者養成講習会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Human papillomavirus (HPV) testing for women treated for CIN2/3 predicts recurrent or residual diseases: a systematic review.2014

    • Author(s)
      Onuki M, Matsumoto K, Nakao S, Sakurai M, Ochi H, Minaguchi T, Satoh T, Yoshikawa H.
    • Organizer
      The 15th Biennial Meeting of the International Gynecologic Cancer Society
    • Place of Presentation
      Melbourne, Australia,
    • Year and Date
      2014-11-08 – 2014-11-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Delivery delay with neoadjuvant chemotherapy for patients with FIGO stage Ib1 cervical cancer during pregnancy: A report of two cases.2014

    • Author(s)
      Tenjimbayashi Y, Minaguchi T, Matsumoto K, Sakurai M, Onuki M, Ochi H, Obata M, Satoh T, Hamada H, Yoshikawa H.
    • Organizer
      The 15th Biennial Meeting of the International Gynecologic Cancer Society
    • Place of Presentation
      Melbourne, Australia,
    • Year and Date
      2014-11-08 – 2014-11-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Recurrence patterns of gastric-type adenocarcinoma (GAS) of the uterine cervix: A subset analysis of the gynecologic cancer study group of the Japan Clinical Oncology Group (JCOG) GAS multicenter study,2014

    • Author(s)
      Nishio S,Mikami Y,Otsuki T,Yaegashi N,Satoh T,Yoshikawa H,Saitoh M,Okamoto A,Kasamatsu T,Miyamoto T,Shiozawa T,Yoshioka Y,Konishi I,Kojima A,Takehara K,Kaneki E,Kobayahi H,Ushijima K,Kamura T.
    • Organizer
      European Society for Medical Oncology, ESMO 2014
    • Place of Presentation
      Madrid,Spain
    • Year and Date
      2014-09-26 – 2014-09-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 子宮頸癌とHPV ー本邦でのワクチン接種開始までー2014

    • Author(s)
      吉川裕之
    • Organizer
      第2回臨床研究教育セミナー
    • Place of Presentation
      宮城
    • Year and Date
      2014-07-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 新規9価HPV L1ウイルス様粒子ワクチンの16~26歳女性における有効性及び免疫原性2014

    • Author(s)
      澤田美由紀、吉川裕之、野田起一郎、田中宜之、Erin Moeller, Michael Ritter, Oliver Bautista, Joshua Chen, Alain Luxembourg
    • Organizer
      第56回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      栃木
    • Year and Date
      2014-07-17 – 2014-07-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 新規9価HPV L1ウイルス様粒子ワクチンの16~26歳女性における安全性及び忍容性2014

    • Author(s)
      田中宜之、吉川裕之、野田起一郎、澤田美由紀、Erin Moeller, Michael Ritter, Oliver Bautista, Joshua Chen, Alain Luxembourg.
    • Organizer
      第56回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      栃木
    • Year and Date
      2014-07-17 – 2014-07-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 子宮頸がんと卵巣がんにおけるNeoadjuvant Chemotherapy2014

    • Author(s)
      吉川裕之
    • Organizer
      第22回鴨和腫瘍カンファレンス
    • Place of Presentation
      京都
    • Year and Date
      2014-06-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] A cohort study of gastric-type adenocarcinoma (GAS) of the uterine cervix: Multi-institutional study by Gynecologic Cancer Study Group of the Japan Clinical Oncology Group (JCOG).2014

    • Author(s)
      Nishio S, Mikami Y, Otsuki T, Yaegashi N, Satoh T, Yoshikawa H, Saito M, Okamoto A, Kasamatsu T, Miyamoto T, Shiozawa T, Yoshioka Y, Konishi I, Kojima A, Nogawa T, Kaneki E, Kobayashi H, Uhsijima K, Kamura T.
    • Organizer
      50th Annual Meeting of American Society Of Clinical Oncology
    • Place of Presentation
      Chicago, Illinois
    • Year and Date
      2014-05-30 – 2014-06-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Comparison of treatment invasiveness between upfront debulking surgery versus interval debulking surgery following neoadjuvant chemotherapy for stage III/IV ovarian, tubal, and peritoneal cancers in phase III randomized trial: JCOG0602. ASCO 2014,2014

    • Author(s)
      Onda T, Yoshikawa H, Shibata T, Nakamura K, Satoh T, Saito T, Kasamatsu T, Nakanishi T, Nogawa T, Saitou M, Ushijima K, Kobayashi H, Takano T, Kawana K, Yokota H, Takano M, Takeshima N, Yaegashi N, Konishi I, Kamura T, japan clinical Oncology Group.
    • Organizer
      50th Annual Meeting of American Society Of Clinical Oncology
    • Place of Presentation
      Chicago, Illinois
    • Year and Date
      2014-05-30 – 2014-06-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] 未来の医療を創る臨床試験―計画・実行の勧め―2014

    • Author(s)
      吉川裕之
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 子宮頸部「胃型腺癌」の後方視的研究2014

    • Author(s)
      西尾 真、牛嶋公生、嘉村敏治、三上芳喜、大槻健郎、八重樫伸生、佐藤豊実、吉川裕之、笠松高弘、斎藤元章、岡本愛光、宮本 強、塩沢丹里、吉岡弓子、小西郁生、小島淳美、野河孝充、兼城英輔、小林裕明
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] ヒトパピローマウイルス(HPV)L2 タンパク質の交差性中和エピトープの解析2014

    • Author(s)
      中尾砂里、松本光司、近藤一成、吉川裕之
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 免疫抑制剤投与中の関節リウマチ患者に発生した子宮頸部類基底細胞癌の一例2014

    • Author(s)
      小宮春奈、越智寛幸、中尾砂里、櫻井 学、小貫麻美子、水口剛雄、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第66回日本産科婦人科学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Mutational status in the PI3K/AKT pathway and efficacy of mTOR inhibitors alone or combined with chemotherapeutics in ovarian clear cell carcinoma cells.2013

    • Author(s)
      Minaguchi T, Akiyama A, Nakamura Y, Tasaka N, Yoahikawa T, Sakurai M, Ochi H, Onuki M, Matsumoto K, Satoh T, Oki A. Yoshikawa H.
    • Organizer
      65th Annual Congress of the Japan Society of Obstetrics and Gynecology
    • Place of Presentation
      Royton Sapporo,Sapporo Geibunkan,Sapporo Prince Hotel,Sapporo Education and Culture Hall(Sapporo)
    • Related Report
      2013 Research-status Report
  • [Presentation] 子宮頸部に浸潤が予測される子宮体癌に対して広汎子宮全摘術は本当に必要か?―後方視的多施設研究(GOTIC_005)―2013

    • Author(s)
      高野政志、越智寛幸、佐藤豊実、吉川裕之、竹井裕二、藤原寛行、鈴木光明、宮本守員、古谷健一、荷見よう子、横田治重、金田佳史、伊藤仁彦、中村和人、峯岸 敬、黒崎 亮、長尾昌二、藤原恵一
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 血清D-dimer 高値は卵巣癌患者の予後不良因子である2013

    • Author(s)
      櫻井 学、佐藤豊実、加藤 敬、秋山 梓、吉川智之、中尾砂里、越智寛幸、小貫麻美子、水口剛雄、松本光司、沖 明典、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における子宮体癌手術の個別化:傍大動脈リンパ節郭清から腹腔鏡下手術まで2013

    • Author(s)
      松本光司、越智寛幸、吉川智之、櫻井 学、小貫麻美子、水口剛雄、佐藤豊実、沖 明典、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] p53 蛋白の異常蓄積は子宮体癌の独立した予後不良因子である2013

    • Author(s)
      秋山 梓、水口剛雄、中村優子、田坂暢崇、中尾砂里、吉川智之、櫻井 学、越智寛幸、小貫麻美子、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 再発子宮体がん患者に対する手術療法選択基準の検討2013

    • Author(s)
      加藤 敬、佐藤豊実、小宮春奈、道上大雄、秋山 梓、櫻井 学、吉川智之、越智寛幸、小貫麻美子、水口剛雄、松本光司、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 手術可能な子宮体癌肺転移再発患者の予後は良好である2013

    • Author(s)
      西田恵子、佐藤豊実、加藤 敬、吉川智之、中尾砂里、櫻井 学、越智寛幸、小貫麻美子、水口剛雄、松本光司、沖 明典、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における腹腔鏡下子宮体がん根治手術(先進医療)の現状2013

    • Author(s)
      越智寛幸、松本光司、小宮春奈、田中勝洋、加藤 敬、吉川智之、中尾砂里、櫻井 学、小貫麻美子、水口剛雄、佐藤豊実、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 卵巣癌患者における血小板増加:臨床病理像・予後との関連2013

    • Author(s)
      小宮春奈、松本光司、吉川智之、櫻井 学、越智寛幸、小貫麻美子、水口剛雄、佐藤豊実、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] 卵巣転移で再発した子宮頸部微小浸潤癌の一例2013

    • Author(s)
      岡崎有香、櫻井 学、玉井はるな、志鎌あゆみ、高野克己、沖 明典、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] DNA 多型解析およびp57KIP2免疫染色にてandrogenetic/ biparental モザイクと考えられた間葉性異形成胎盤の1 例2013

    • Author(s)
      小倉 剛、塩浦加奈、田中勝洋、八木洋也、安部加奈子、永井優子、小畠真奈、濱田洋実、吉川裕之
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館(旧北海道厚生年金会館)、札幌プリンスホテル、札幌市教育文化会館(札幌)
    • Related Report
      2013 Research-status Report
  • [Presentation] TACAS標本の免疫染色による子宮内膜病変の悪性度判定の試み2013

    • Author(s)
      中村優子、道上大雄、中川智貴、藤原広美、深沢政勝、里見介史、菅野雅人、南 優子、吉川裕之、野口雅之
    • Organizer
      第54回日本臨床細胞学会(春期大会)
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における先進医療「腹腔鏡下子宮体がん根治術」の現状2013

    • Author(s)
      松本光司、越智寛幸、小貫麻美子、中尾砂里、櫻井 学、前山哲朗、小関 剛、岡崎有香、飯場萌絵、佐々木怜子、西田恵子、水口剛雄、佐藤豊実、吉川裕之
    • Organizer
      第173回茨城産科婦人科学会
    • Place of Presentation
      つくば国際会議場(つくば)
    • Related Report
      2013 Research-status Report
  • [Presentation] 4回の再発腫瘍摘出術を経て長期生存が得られている卵巣癌IIIc期の1例2013

    • Author(s)
      天神林友梨、櫻井 学、前山哲朗、野口里枝、中尾砂里、越智寛幸、小貫麻美子、水口剛雄、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第125回関東連合産科婦人科学会総会・学術集会
    • Place of Presentation
      日本都市センターホテル(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 類内膜腺癌に漿液性境界悪性腫瘍・明細胞癌が共存する卵巣腫瘍を伴った子宮体部類内膜腺癌2013

    • Author(s)
      天神林友梨、越智寛幸、野口里枝、櫻井 学、中尾砂里、小貫麻美子、水口剛雄、松本光司、佐藤豊実、坂田晃子、吉川裕之
    • Organizer
      第54回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      ホテル グランパシフィック LE DAIBA(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] エベロリムス内服中のインスリノーマ合併子宮体癌の1例 - 周術期管理の経験 -2013

    • Author(s)
      岡崎有香、越智寛幸、野口里枝、中尾砂理、櫻井 学、小貫麻美子、水口剛雄、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第53回日本産科婦人科内視鏡学会学術講演会
    • Place of Presentation
      城山観光ホテル(名古屋)
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における先進医療「腹腔鏡下子宮体がん根治術」の現状2013

    • Author(s)
      松本光司、越智寛幸、小貫麻美子、中尾砂理、櫻井 学、水口剛雄、佐藤豊実、吉川裕之
    • Organizer
      第36回日本産科婦人科手術学会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 再発卵巣がんの手術2013

    • Author(s)
      佐藤豊実、櫻井 学、中尾砂理、越智寛幸、小貫麻美子、水口剛雄、松本光司、吉川裕之
    • Organizer
      第36回日本産科婦人科手術学会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 上腹部正中切開法が有用と考えられた病的肥満卵巣癌患者の1 例2013

    • Author(s)
      飯場萌絵、越智寛幸、佐々木怜子、西田恵子、岡崎有香、前山哲朗、小関 剛、野口里枝、中尾砂理、櫻井学、小貫麻美子、水口剛雄、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第36回日本産科婦人科手術学会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 卵巣癌治療における手術2013

    • Author(s)
      吉川裕之
    • Organizer
      第36回日本産科婦人科手術学会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 腫瘍免疫逃避における可溶型CD155 の機能解析2013

    • Author(s)
      井口研子、小島 寛、吉川裕之、渋谷 彰、渋谷和子
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2013 Research-status Report
  • [Presentation] p53 蛋白の異常蓄積は子宮体癌の独立した予後不良因子である2013

    • Author(s)
      秋山 梓、水口剛雄、志鎌あゆみ、中尾砂理、越智寛幸、小貫麻美子、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 妊娠に合併した子宮頸癌 Ib 1期に対し NAC 後に帝切術および広汎子宮全摘術を施行した 1 例2013

    • Author(s)
      天神林友梨、水口剛雄、前山哲朗、中尾砂里、八木洋也、越智寛幸、小貫麻美子、小畠真奈、松本光司、佐藤豊実、濱田洋実、吉川裕之
    • Organizer
      第126回関東連合産科婦人科学会総会・学術集会
    • Place of Presentation
      アクトシティ浜松(浜松市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 家族歴の再確認により遺伝子検査を行い,既治療の卵巣癌患者を遺伝性乳がん・卵巣がん(HBOC)と診断した 2 例2013

    • Author(s)
      佐々木怜子、佐藤豊実、飯場萌絵、岡崎有香、前山哲朗、中尾砂里、櫻井 学、越智寛幸、小貫麻美子、水口剛雄、松本光司、吉川裕之
    • Organizer
      第126回関東連合産科婦人科学会総会・学術集会
    • Place of Presentation
      アクトシティ浜松(浜松市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 顆粒膜細胞腫と鑑別を要した閉経後卵巣癌の 2症例2013

    • Author(s)
      佐藤愛佳、小貫麻美子、岡崎有香、櫻井 学、中尾砂里、越智寛幸、水口剛雄、松本光司、佐藤豊実、吉川裕之
    • Organizer
      第126回関東連合産科婦人科学会総会・学術集会
    • Place of Presentation
      アクトシティ浜松(浜松市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における先進医療「腹腔鏡下子宮体がん根治術」の現状2013

    • Author(s)
      松本光司、越智寛幸、小貫麻美子、中尾砂里、櫻井 学、前山哲朗、小関 剛、岡崎有香、飯場萌絵、佐々木怜子、西田恵子、水口剛雄、佐藤豊美、吉川裕之
    • Organizer
      第174回茨城産科婦人科学会
    • Place of Presentation
      茨城医師会(水戸市)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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