Assisting system for surgical and examination endoscopy using virtual reality with internal information obtained by OCT

• Project/Area Number: 25670716
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Kyoto University
• Principal Investigator: ITO Juichi 京都大学, 医学(系)研究科(研究院), 名誉教授 (90176339)
• Co-Investigator(Kenkyū-buntansha): SAKAMOTO Tatsunori 京都大学, 医学研究科, 助教 (60425626) ; KURODA Tomohiro 京都大学, 医学研究科, 教授 (10304156) ; KUME Naoto 京都大学, 情報学研究科, 准教授 (00456881) ; TATEYA Ichiro 京都大学, 医学研究科, 講師 (20526363) ; NAKAGAWA Takayuki 京都大学, 医学研究科, 講師 (50335270) ; KITAMURA Morimasa 京都大学, 医学研究科, 助教 (60543262) ; YAMAMOTO Norio 京都大学, 医学研究科, 助教 (70378644) ; HIRANO Shigeru 京都大学, 医学研究科, 准教授 (10303827) ; HIRAUMI Harukazu 岩手医科大学, 医学部, 講師 (10374167)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 画像診断 / 光コヒーレンストモグラフィー / 内視鏡

Outline of Final Research Achievements

New optical system, that can obtain endoscopic images and OCT images through the same light path, has been developed and implemented. Computer programs to extract internal structural information from the set of OCT cross-sectinal images, to convert into en-face images, and to overlay on the endoscopic images are being developed. Using olfactory damage mice system as a working animal model, the ability of OCT to visualize olfactory dysfunction. A computer program that can extract pathological morphology in the mouse cochleae has been developed. These OCT information is intended to be overlapped onto endoscopic images to enable clear visualization of internal structures and/or functions.

Research Products

• [Presentation] 光コヒーレンストモグラフィー (OCT)を用いた内耳画像診断 (2014)
  • Author(s): 坂本達則, 十名洋介, 田浦晶子, 中川隆之, 伊藤壽一
  • Organizer: 第73回めまい平衡医学会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-11-05 – 2014-11-07
• [Presentation] Nondestructive Observation of the Vestibular Systems of Slc26a4 K.O. Mice Using Optical Coherence Tomography (OCT) (2014)
  • Author(s): Sakamoto T, Tona Y, Taura A, Nakagawa T, Ito J
  • Organizer: Inner Ear Biology Workshop 2014 in Kyoto
  • Place of Presentation: 国立京都国際会館（京都市）
  • Year and Date: 2014-11-01 – 2014-11-04
• [Presentation] 光コヒーレンストモグラフィー(OCT)を用いた 耳石器の観察 (2014)
  • Author(s): 坂本達則, 十名洋介, 田浦晶子, 中川隆之, 伊藤壽一
  • Organizer: 第24回日本耳科学会
  • Place of Presentation: 朱鷺メッセ（新潟市）
  • Year and Date: 2014-10-16 – 2014-10-18
• [Presentation] Visualization of Maculae and Membranous Semicircular Ducts in the Otic Capsule by Optical Coherence Tomography (OCT) (2014)
  • Author(s): Sakamoto T, Tona Y, Nakagawa T, Ito J
  • Organizer: AAO-HNSF Annual Meeting
  • Place of Presentation: Orlando, U.S.
  • Year and Date: 2014-09-20 – 2014-09-24
• [Presentation] Visualization of the internal structures of the inner ear by optical coherence tomography (OCT) (2014)
  • Author(s): Sakamoto T, Tona Y, Nakagawa T, Ito J
  • Organizer: 15th KOREA JAPAN Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2014-04-04 – 2014-04-06