| Project/Area Number |
25670724
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
NAGAOKA Taiji 旭川医科大学, 医学部, 准教授 (00333691)
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| Co-Investigator(Kenkyū-buntansha) |
ONO Shinji 旭川医科大学, 大学病院, 医員 (50571890)
YOSHIOKA Takafumi 旭川医科大学, 大学病院, 医員 (20548854)
OTANI Shinichi 旭川医科大学, 大学病院, 医員 (70548841)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 網膜循環 / 血管内皮 / 一酸化窒素 / 網膜循環調節 / 硫化水素 / 微小循環生理 |
|---|
| Outline of Final Research Achievements |
In this study, we examined the roles of NO, CO, and H2S in the regulation of retinal blood flow. Our data demonstrate that NO plays an important role in the regulation of retinal blood flow. In contrast, we could not find that CO and H2S have any influences on the regulation of retinal blood flow. Further study is needed to examine the detailed mechanisms of Co and H2S in retinal blood flow using more powerful donors of CO and H2S.
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