| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The present study aimed to evaluate the effect of the functional foods for prevention of osteoporosis. We established osteoporosis model rat using ovariectomy operation. Sham operation was used for control. Before or after operation, Functional foods were fed to model animals. Two, 4 and 8 weeks after operation, Tibiae and femurs were collected. Samples were analyzed by micro-CT, three point bending test and Histological staining. Micro-CT images showed that cancellous bone mass in OVX-rats were decreasing from 4 weeks and reached 50% on 8 weeks after operation. Histological sections indicated that bone mineral density and amount of crosslinking were increased in Royal jelly diet and black vinegar diet samples. However, Bone volume and Breaking strength in Royal jelly diet and black vinegar diet samples showed no difference compare to the control.
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