Development of treatment for occlusal dysethesia with botulinum toxin
Project/Area Number |
25670821
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Prosthodontics/ Dental materials science and
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Research Institution | The University of Tokushima |
Principal Investigator |
MATSUKA Yoshizo 徳島大学, 大学院医歯薬学研究部, 教授 (90243477)
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Co-Investigator(Kenkyū-buntansha) |
KAJI Ryuji 徳島大学, 大学院医歯薬学研究部, 教授 (00214304)
SHIGEMOTO Shuji 徳島大学, 大学院医歯薬学研究部, 助教 (20294704)
SUZUKI Yoshitaka 徳島大学, 大学院医歯薬学研究部, 助教 (40581393)
OKURA Kazuo 徳島大学, 大学院医歯薬学研究部, 講師 (70304540)
TAKEUCHI Hisahiro 徳島大学, 病院, 講師 (10222093)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 咬合感覚異常 / ボツリヌス毒素 / ブラキシズム / 口腔顔面痛 / 咬合異常感覚 |
Outline of Final Research Achievements |
Occlusal dysethesia patient (1. complain occlusal contact abnormality at central occlusion more than 6 months, 2. patient can point the problem tooth) who agreed the boltulinum toxin treatment was injected botulinum toxin after masseter muscle activity recording. The occlusal abnormal sensation was measured with Visual Analogue Scale(VAS). After boltulinum toxin injection, orofacial pain was decreased but occlusal dysethesia sensation was not decreased significantly.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Japan Prosthodontic Society position paper on ‘‘occlusal discomfort syndrome''2016
Author(s)
Tamaki K, Ishigaki S, Ogawa T, Oguchi H, Kato T, Suganuma T, Shimada A, Sadamori S, Tsukiyama Y, Nishikawa Y, Masumi S, Yamaguchi T, Aita H, Ono T, Kondo H, Tsukasaki H, Fueki K, Fujisawa M, Matsuka Y, Baba K, Koyano K
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Journal Title
Journal of Prosthodontic Research
Volume: 60
Issue: 3
Pages: 156-166
DOI
NAID
ISSN
1883-1958, 1883-9207
Year and Date
2016-07-25
Related Report
Peer Reviewed / Open Access
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[Journal Article] Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control2014
Author(s)
Hajime Minakuchi, Chiharu Sogawa C, Emilio Satoshi Hara, Haruna Miki, Kenji Maekawa, Norio Sogawa, Shigeo Kitayama, Yoshizo Matsuka, Glenn T Clark, Takuo Kuboki
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Journal Title
Journal of Prosthodontic Research
Volume: 58
Issue: 4
Pages: 217-222
DOI
NAID
ISSN
1883-1958, 1883-9207
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] Botulinum toxin endocytosed trigeminal neurons alleviates neuropathic pain2013
Author(s)
Omoto K, Suzuki Y, Maruhama K, Yamamoto Y, Terayama R, Spigelman I, Kamioka H, Maekawa K, Sugimoto T, Matsushita O, Kuboki T, Matsuka Y
Organizer
Asia Academic Congress for Temporomandibular Joint
Place of Presentation
International Communication Branch (China)
Related Report
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