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Challenging attempts of prevention of certain cleft palate only: An idea for clinical application of epidemiological results.

Research Project

Project/Area Number 25670866
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionAichi Gakuin University

Principal Investigator

Natsume Nagato  愛知学院大学, 歯学部, 教授 (90183532)

Co-Investigator(Renkei-kenkyūsha) IMURA HIDETO  愛知学院大学, 歯学部, 講師 (10513187)
HAYAKAWA TOKO  愛知学院大学, 心身科学部, 講師 (90609710)
Research Collaborator OZEKI SATORU  独立行政法人国立病院機構九州医療センター, 口腔腫瘍・口腔ケアセンター, 口腔腫瘍センター統括長 (80117077)
MITUYASU TAKESHI  九州大学, 大学病院, 助教 (00380519)
NIIMI TERUYUKI  愛知学院大学, 歯学部, 准教授 (60291762)
MINAMI KATSUHIRO  愛知学院大学, 歯学部, 講師 (70346162)
ONO MAYA  愛知学院大学, 歯学部, 非常勤助教 (70760718)
AKASHI Junko  愛知学院大学, 歯学部, 非常勤助教
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords口蓋裂 / 予防 / 疫学 / 産み分け / 遺伝カウンセリング / 口蓋裂予防 / 粘膜下口蓋裂
Outline of Final Research Achievements

I have been studying cleft lip and/or palate epidemiologically for 30 years. This time, I performed detailed epidemiological study on familial cleft palate (CP). As a result, I got a new finding which has never been reported elsewhere, that is, no boys were born from parents with CP, and, when the first child had been a girl with CP, most of the second child was healthy if the second child was a boy.
We performed a questionnaire study on the basis of above finding. We asked the office of International Cleft Lip and Palate Foundation (ICPF), of which we are the members, to send questionnaire sheets to other members. We got some data from Japan, Russia, Germany, Finland, Mexico, Saudi Arabia, Singapore. The number of the data, however, was too small and we could not confirm the phenomenon we found with Japanese patient families. We will continue to collect data to accumulate the number of the patient families.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (10 results)

All 2016 2015 2014 Other

All Int'l Joint Research (6 results) Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results)

  • [Int'l Joint Research] Bashkir State Medical University(ロシア連邦)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] University of Tampere/University of Oulu(フィンランド)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Goethe-Universitat Frankfurt am Main(ドイツ)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] King Saud University(サウジアラビア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] National University of Singapore(シンガポール)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 粘膜下口蓋裂に関する臨床的検討2016

    • Author(s)
      井村英人,夏目長門,新美照幸,古川博雄,南克浩,鈴木聡,大野磨弥,森明弘,中原晋一,早川統子,佐久間千里,山内楓子,江尻彰啓,栗田賢一
    • Journal Title

      愛知学院大学歯学会誌

      Volume: 54(2)

    • NAID

      40020932229

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] 口唇口蓋裂患者とその家族に対する遺伝カウンセリングの現状第5報出生前カウンセリングについて2015

    • Author(s)
      井村英人,夏目長門,山本正彦,鈴木聡,藤原久美子,大野磨弥,佐久間千里,早川統子
    • Organizer
      第55回日本先天異常学会学術集会
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川県横浜市)
    • Year and Date
      2015-07-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] 口腔先天異常に関する遺伝カウンセリングの実態調査2014

    • Author(s)
      井村英人,藤原久美子,山本正彦、鈴木聡,加藤大貴,大野磨弥,森明弘,古川博雄,新美照幸,早川統子,夏目長門
    • Organizer
      第54回日本先天異常学会学術集会
    • Place of Presentation
      神奈川
    • Year and Date
      2014-07-27 – 2014-07-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 口唇・口蓋裂患者に関する疫学的研究第58報:口唇口蓋裂患者1843例中の口蓋裂家族内発現率2014

    • Author(s)
      夏目長門,加藤大貴,大野磨弥,森明弘,長瀬好和,石川拓,秋山芳夫,菅原利夫.井村英人,早川統子.南克浩,河合幹
    • Organizer
      第38回日本口蓋裂学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-29 – 2014-05-30
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2022-01-31  

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