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Evaluation of hypothesis which a malocclusion is caused by perception disorder and hypokinesia of pharynx, esophagus and stomach

Research Project

Project/Area Number 25670879
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthodontics/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

MIYAWAKI Shouichi  鹿児島大学, 医歯(薬)学総合研究科, 教授 (80295807)

Co-Investigator(Kenkyū-buntansha) MAEDA Aya  鹿児島大学, 医歯学総合研究科, 助教 (10457666)
NAGAYAMA Kunihiro  鹿児島大学, 医学部・歯学部附属病院, 助教 (60583458)
OOMURE Haruhito  鹿児島大学, 医歯学総合研究科, 講師 (00404484)
YAGI Takakazu  鹿児島大学, 医学部・歯学部附属病院, 講師 (10346166)
UEDA Hirotaka  鹿児島大学, 医歯学総合研究科, 助教 (10583445)
上原 沢子  鹿児島大学, 医学部・歯学部附属病院, 医員 (50706257)
Co-Investigator(Renkei-kenkyūsha) UEHARA Sawako  鹿児島大学, 医学部・歯学部附属病院, 医員 (50706257)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords不正咬合 / 顎運動 / 咀嚼機能 / 迷走神経 / 内臓感覚 / 唾液 / 歯学 / 咽頭・食道・胃の知覚 / 胃食道逆流 / 咬筋
Outline of Final Research Achievements

Clinical research: we evaluated the relationship between a stomatognathic function, which closely relate with gastrointestinal function, and a malocclusion. In the patients with scissors-bite, the chewing pattern and activities of both the temporalis and the masseter muscles were significantly narrower and lower, respectively. In the patients with molar cross-bite, the reverse chewing pattern during deliberate unilateral mastication was significantly more frequently observed. Those results suggest that gastrointestinal function in patients with scissors-bite or cross-bite malocclusion may be low.
Basic research: we focused on the vagal nerve dominating the visceral sensation. As a result of cervical vagal stimulation, it was observed the rhythmic muscle activity of mylohyoid which means swallowing with salivary secretion. From this study, it was suggested that visceral sensation is involved in activation of stomatognathic functions including salivation and swallowing.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2013

All Journal Article (5 results) (of which Peer Reviewed: 4 results) Presentation (10 results) (of which Invited: 1 results)

  • [Journal Article] First molar crossbite is more closely associated with a reverse chewing cycle than anterior or premolar crossbite during mastication2015

    • Author(s)
      H Tomonari, T Ikemori, T Kubota, S Uehara, S Miyawaki
    • Journal Title

      J Oral Rehabil

      Volume: 41 Issue: 12 Pages: 890-896

    • DOI

      10.1111/joor.12222

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Posterior scissors-bite: masticatory jaw movement and muscle activity2014

    • Author(s)
      Tomonari H, Kubota T, Yagi T, Kuninori T, Kitashima F, Uehara S, Miyawaki S
    • Journal Title

      Journal of oral rehabilitation

      Volume: Apr;41(4) Issue: 4 Pages: 257-65

    • DOI

      10.1111/joor.12148

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in grafted autogenous bone during edgewise treatment in patients with unilateral cleft lip/palate or alveolus.2014

    • Author(s)
      Maeda A, Uehara S, Suga M, Nishihara K, Nakamura N, Miyawaki S.
    • Journal Title

      Cleft Palate Craniofac J

      Volume: in press Issue: 5 Pages: 525-532

    • DOI

      10.1597/12-281

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of experimental esophageal acidification on masseter muscle activity, cervicofacial behavior, and autonomic nervous activity in wakefulness2014

    • Author(s)
      Ohmure H, Sakoguchi Y, Nagayama K, Numata M, Tsubouch H, Miyawaki S
    • Journal Title

      J Oral Rehabil

      Volume: (Epub ahead of print) Issue: 6 Pages: 423-431

    • DOI

      10.1111/joor.12159

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 酸蝕症とブラキシズム2014

    • Author(s)
      宮脇正一, 植田紘貴, 前田 綾.
    • Journal Title

      小児歯科臨床

      Volume: 19 Pages: 38-42

    • Related Report
      2013 Research-status Report
  • [Presentation] 胃酸分泌抑制剤が睡眠時ブラキシズムに与える影響.2014

    • Author(s)
      橋本恭子,大牟禮治人,永山邦宏,沼田政嗣,井戸章雄,宮脇正一.
    • Organizer
      第73回日本矯正歯科学会大会
    • Place of Presentation
      千葉(幕張メッセ)
    • Year and Date
      2014-10-20 – 2014-10-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胃酸分泌抑制と唾液分泌促進の二相性効果について-H2受容体拮抗薬による自律神経活動の促進-.2014

    • Author(s)
      植田紘貴、菅 真有,八木孝和,宮脇正一.
    • Organizer
      第73回日本矯正歯科学会大会
    • Place of Presentation
      千葉(幕張メッセ)
    • Year and Date
      2014-10-20 – 2014-10-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 外科的矯正治療を行った小下顎症と顎関節強直症を伴う症例.2014

    • Author(s)
      高田寛子,友成博,松井竜太郎,杉原一正,宮脇正一.
    • Organizer
      日本顎変形症学会学術大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2014-06-10 – 2014-06-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] シンポジウム2 「顎変形患者の心理」2014

    • Author(s)
      植田紘貴.
    • Organizer
      第24回日本顎変形症学会総会・学術大会 シンポジウム2 「顎変形患者の心理」 シンポジスト 2014年 6月11日 福岡
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2014-06-10 – 2014-06-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 第一大臼歯に発現する交叉咬合は逆ストロークの咀嚼パターンと異常な閉口筋活動に関連する.2014

    • Author(s)
      池森宇泰, 友成博, 八木孝和, 窪田健司, 上原沢子, 高田寛子, 宮脇正一.
    • Organizer
      第24回日本顎変形症学会学術大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2014-06-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 歯科矯正治療による片側性唇顎口蓋裂を伴う患者の移植骨の変化:過去30年間における治療結果の長期的評価.2014

    • Author(s)
      前田 綾,上原沢子,菅真 有,西原一秀,中村典史,宮脇正一.
    • Organizer
      第38回日本口蓋裂学会総会・学術集会
    • Place of Presentation
      札幌(札幌コンベンションセンター)
    • Year and Date
      2014-05-29 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] ラット食道粘膜への酸刺激における咬筋筋活動と侵害受容器の発現亢進について2014

    • Author(s)
      上村裕希,八木孝和,北嶋文哲,浅川明弘,乾 明夫,宮脇正一.
    • Organizer
      第9回九州矯正歯科学会大会
    • Place of Presentation
      沖縄
    • Related Report
      2013 Research-status Report
  • [Presentation] 開咬患者の胃食道逆流症状について-質問紙調査による検討-2014

    • Author(s)
      高田寛子,大牟禮治人,池森宇泰,小柳宏太郎,上原沢子,宮脇正一.
    • Organizer
      第9回九州矯正歯科学会大会
    • Place of Presentation
      沖縄
    • Related Report
      2013 Research-status Report
  • [Presentation] 唾液分泌はいかに制御されるか?-内臓感覚と胃酸分泌抑制剤ニザチジンの新たな関係-.2014

    • Author(s)
      植田紘貴,菅 真有,八木孝和,大賀泰彦,宮脇正一.
    • Organizer
      第9回九州矯正歯科学会大会
    • Place of Presentation
      沖縄
    • Related Report
      2013 Research-status Report
  • [Presentation] 胃酸分泌抑制剤ニザチジンの唾液分泌促進剤としての可能性-中枢への作用と内臓感覚との関連-2013

    • Author(s)
      植田紘貴,菅真有,八木孝和,宮脇正一.
    • Organizer
      第72回日本矯正歯科学会大会
    • Place of Presentation
      長野
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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