Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2013: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
|
Outline of Final Research Achievements |
The identification of interactions between drugs and target proteins is a key area in genomic drug discovery. Various high-throughput experimental projects enable us to analyze the genome, transcriptome, proteome. At the same time, the high-throughput screening of large-scale chemical compound libraries with various biological assays produce chemical and phenotypic data on drugs and bioactive compounds. In this project, we develop machine learning methods to infer unknown drug-target interactions by integrating various large-scale omics data.
|