Budget Amount *help |
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2015: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2014: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2013: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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Outline of Final Research Achievements |
Most bacteria release membrane vesicles (MVs) to the environment. These MVs are reported to have various functions that are important to the biological system, while they are not fully understood. During this project we have revealed a novel mechanism of how these MVs are released from the cell. Furthermore, we found that MVs can carry hydrophobic cell-cell communication signals (long chain AHLs), that will trigger the gene expression of the MV receiving cells. MVs showed some tendency to attach to the same species. Our data will allow us to understand the MV driven bacterial interactions and could also serve as a platform for nanotechnology.
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