Brain-derived neurotrophic factor as predictor of depression, and dietary and nutritional factors in a Japanese working population
Project/Area Number |
25702006
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Partial Multi-year Fund |
Research Field |
Eating habits
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Research Institution | National Center for Global Health and Medicine |
Principal Investigator |
NANRI Akiko 国立研究開発法人国立国際医療研究センター, 疫学・予防研究科, 室長 (80523646)
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Research Collaborator |
MIZOUE Tetsuya 国立国際医療研究センター, 疫学・予防研究科, 科長
MIKI Takako 国立国際医療研究センター, 疫学・予防研究科, 研究員
KUROTANI Kayo 国立国際医療研究センター, 疫学・予防研究科, 上級研究員
KUWAHARA Keisuke 帝京大学, 公衆衛生大学院, 助教
Akter Shamima 国立国際医療研究センター, 疫学・予防研究科, 研究員
KASHINO Ikuko 国立国際医療研究センター, 疫学・予防研究科, 研究員
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2013: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
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Keywords | うつ / BDNF / 葉酸 / ビタミンD / 食事パターン / 職域 / 栄養疫学 / 食事 |
Outline of Final Research Achievements |
This study was aimed to examine the association of dietary and nutritional factors and dietary patterns with serum brain-derived neurotrophic factor (BDNF) among 2162 men and women who participated in a health survey. Participants were asked to fill out two types of survey questionnaire (for diet and for overall health-related lifestyle) and to donate venous blood. Serum concentrations of folate and 25-hydroxyvitamin D and dietary intakes of docosahexaenoic acid and eicosapentaenoic acid were not associated with serum BDNF concentrations. For dietary pattern analysis, a healthy dietary pattern characterized by high intakes of vegetables, fruits, mushrooms, potatoes, seaweeds, soy products was associated with lower concentrations of BDNF.
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Report
(5 results)
Research Products
(14 results)
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[Journal Article] Dietary fiber intake and depressive symptoms in Japanese employees: The Furukawa Nutrition and Health Study2016
Author(s)
Miki T, Eguchi M, Kurotani K, Kochi T, Kuwahara K, Ito R, Kimura Y, Tsuruoka H, Akter S, Kashino I, Kabe I, Kawakami N, Mizoue T
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Journal Title
Nutrition
Volume: 32
Issue: 5
Pages: 584-589
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Dietary patterns derived by reduced rank regression (RRR) and depressive symptoms in Japanese employees: The Furukawa nutrition and health study2015
Author(s)
Miki T, Kochi T, Kuwahara K, Eguchi M, Kurotani K, Tsuruoka H, Ito R, Kabe I, Kawakami N, Mizoue T, Nanri A
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Journal Title
Psychiatry Resarch
Volume: 229
Issue: 1-2
Pages: 214-219
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] High dietary acid load is associated with increased prevalence of hypertension: the Furukawa Nutrition and Health Study2015
Author(s)
Akter S, Eguchi M, Kurotani K, Kochi T, Pham NM, Ito R, Kuwahara K, Tsuruoka H, Mizoue T, Kabe I, Nanri A
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Journal Title
Nutrition
Volume: 31
Issue: 2
Pages: 298-303
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Dietary patterns and sleep symptoms in Japanese workers: the Furukawa Nutrition and Health Study2015
Author(s)
Kurotani K, Kochi T, Nanri A, Eguchi M, Kuwahara K, Tsuruoka H, Akter S, Ito R, Pham NM, Kabe I, Mizoue T
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Journal Title
Sleep Med
Volume: 16
Issue: 2
Pages: 298-304
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Dietary intake of minerals in relation to depressive symptoms in Japanese employees: The Furukawa Nutrition and Health Study2015
Author(s)
Miki T, Kochi T, Eguchi M, Kuwahara K, Tsuruoka H, Kurotani K, Ito R, Akter S, Kashino I, Pham NM, Kabe I, Kawakami N, Mizoue T, Nanri A
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Journal Title
Nutrition
Volume: 31
Issue: 5
Pages: 686-690
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Macronutrient intake and depressive symptoms among Japanese male workers: the Furukawa Nutrition and Health Study2014
Author(s)
Nanri A, Eguchi M, Kuwahara K, Kochi T, Kurotani K, Ito R, Pham NM, Tsuruoka H, Akter S, Jacka F, Mizoue T, Kabe I
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Journal Title
Psychiatry Res
Volume: 220
Issue: 1-2
Pages: 263-268
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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