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Development of a stimulated Raman spectral microscope for the analysis of small biomolecules in live cells and tissues

Research Project

Project/Area Number 25702026
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionThe University of Tokyo

Principal Investigator

Ozeki Yasuyuki  東京大学, 工学(系)研究科(研究院), 准教授 (60437374)

Research Collaborator HASHIMOTO Hiroyuki  キヤノン(株), 主席研究員
SAKAMOTO Michiie  慶応大学, 医学部病理学教室, 教授
YOKOYAMA Hiroyuki  東北大学, NICHe, 教授
GODA Keisuke  東京大学, 理学系研究科, 教授
EGAWA Mariko  資生堂, ライフサイエンス研究センター, 副主任研究員
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥25,350,000 (Direct Cost: ¥19,500,000、Indirect Cost: ¥5,850,000)
Fiscal Year 2016: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Keywords誘導ラマン散乱 / 生体顕微鏡 / 生体観察
Outline of Final Research Achievements

We utilized a stimulated Raman scattering (SRS) microscope to observe living cells and tissues and to investigate the behavior of small molecules such as lipids and polysaccharides. In addition, we improved the performance of our SRS microscope and developed new laser light sources. As a result, we succeeded in visualizing lipids and polysaccharides contained in living microalgae without labeling, and discriminating between plural kinds of cells contained in skin tissues without labeling. Furthermore, we successfully demonstrated SRS imaging using a semiconductor laser diode capable of long-term stable operation and developed a new high-speed wavelength-tunable fiber laser. These results will broaden the possibility of biomedical imaging and make this technology more practical.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (55 results)

All 2017 2016 2015 2014 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results,  Open Access: 3 results,  Acknowledgement Compliant: 3 results) Presentation (45 results) (of which Int'l Joint Research: 17 results,  Invited: 25 results) Remarks (3 results)

  • [Journal Article] Generation of synchronized picosecond pulses by a 1.06-um gain-switched laser diode for stimulated Raman scattering microscopy2016

    • Author(s)
      K. Tokunaga, Y. -C. Fang, H. Yokoyama, and Y. Ozeki
    • Journal Title

      Optics Express

      Volume: 24 Issue: 9 Pages: 9617-9628

    • DOI

      10.1364/oe.24.009617

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Probing the metabolic heterogeneity of live Euglena gracilis with stimulated Raman scattering microscopy2016

    • Author(s)
      Y. Wakisaka, Y. Suzuki, O. Iwata, A. Nakashima, T. Ito, M. Hirose, R. Domon, M. Sugawara, N. Tsumura, H. Watarai, T. Shimobaba, K. Suzuki, K. Goda, Y. Ozeki
    • Journal Title

      Nature Microbiology

      Volume: 1 Issue: 10 Pages: 16124-16124

    • DOI

      10.1038/nmicrobiol.2016.124

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] In situ visualization of intracellular morphology of epidermal cells using stimulated Raman scattering microscopy2016

    • Author(s)
      M. Egawa, K. Tokunaga, J. Hosoi, S. Iwanaga, and Y. Ozeki
    • Journal Title

      Journal of Biomedical Optics

      Volume: 21 Issue: 08 Pages: 086017-086017

    • DOI

      10.1117/1.jbo.21.8.086017

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fast wavelength-tunable picosecond pulses from a passively mode-locked Er fiber laser using a galvanometer-driven intracavity filter2015

    • Author(s)
      Y. Ozeki and D. Tashiro
    • Journal Title

      Optics Express

      Volume: 23 Issue: 12 Pages: 15186-15194

    • DOI

      10.1364/oe.23.015186

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] On-line visualization of multicolor chemical images with stimulated Raman scattering spectral microscopy2015

    • Author(s)
      Y. Otsuka, K. Makara, S. Satoh, H. Hashimoto and Y. Ozeki
    • Journal Title

      Analyst

      Volume: 140 Issue: 9 Pages: 2984-2987

    • DOI

      10.1039/c5an00335k

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Stimulated Raman spectral microscope using synchronized Er- and Yb-fiber lasers.2014

    • Author(s)
      Nose, K., Kishi, T., Ozeki, Y., Kanematsu, Y., Takata, H.,Fukui, K., Takai, Y. and Itoh, K.
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 53 Issue: 5 Pages: 52401-52401

    • DOI

      10.7567/jjap.53.052401

    • NAID

      210000143745

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Label-free visualization of acetaminophen-induced liver injury by high-speed stimulated Raman scattering spectral microscopy and multivariate image analysis2014

    • Author(s)
      S. Satoh, Y. Otsuka, Y. Ozeki, K. Itoh, A. Hashiguchi, K. Yamazaki, H. Hashimoto and M. Sakamoto
    • Journal Title

      Pathology Int.

      Volume: 64 Issue: 10 Pages: 518-526

    • DOI

      10.1111/pin.12206

    • Related Report
      2014 Annual Research Report
    • Open Access
  • [Presentation] Fast Wavelength-Switchable Figure-Nine Er Fiber Laser Using a Galvanometer-Driven Intracavity Filter2017

    • Author(s)
      Y. Ozeki and T. Fujita
    • Organizer
      CLEO:2017
    • Place of Presentation
      サンノゼ(米国)
    • Year and Date
      2017-05-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Stimulated Raman Scattering Microscopy for Label-free Chemical Imaging of Cells and Tissues2017

    • Author(s)
      Y. Ozeki
    • Organizer
      AnalytiX-2017, Session 3-2-6
    • Place of Presentation
      福岡市
    • Year and Date
      2017-03-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ガルバノスキャナを用いた高速波長切り替えfigure-9レーザ2017

    • Author(s)
      藤田 敏郎、小関 泰之
    • Organizer
      第64回応用物理学会春季学術講演会、17a-P2-4
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] High-speed stimulated Raman scattering microscopy for studying the metabolic diversity of motile Euglena gracilis2017

    • Author(s)
      Y. Suzuki, Y. Wakisaka, O. Iwata, A. Nakashima, T. Ito, M. Hirose, R. Domon, M. Sugawara, N. Tsumura, H. Watarai, T. Shimobaba, K. Suzuki, K. Goda and Y. Ozeki
    • Organizer
      SPIE Photonics West, BiOS, High-Speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management II
    • Place of Presentation
      サンフランシスコ(米国)
    • Year and Date
      2017-01-30
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Metabolite imaging of microalgae with stimulated Raman scattering microscopy2016

    • Author(s)
      Y. Ozeki, Y. Wakisaka, Y. Suzuki, and K. Goda
    • Organizer
      72nd Annual Southwest Regional Meeting of Americas Chemical Society, Symposium on Applications of Photonics in Energy & Life Sciences, paper 460
    • Place of Presentation
      ガルベストン(米国)
    • Year and Date
      2016-11-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 誘導ラマン散乱による生きたユーグレナの1細胞代謝物解析2016

    • Author(s)
      小関泰之、鈴木祐太、脇坂佳史、合田圭介
    • Organizer
      第32回ユーグレナ研究会
    • Place of Presentation
      東京大学農学部キャンパス
    • Year and Date
      2016-11-10
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Label-free imaging and statistical analysis of the metabolic heterogeneity of live Euglena gracilis with stimulated Raman scattering microscopy2016

    • Author(s)
      Y. Suzuki, Y. Wakisaka, O. Iwata, A. Nakashima, K. Suzuki, T. Ito, M. Hirose, R. Domon, M. Sugawara, N. Tsumura, H. Watarai, T. Shimobaba, K. Goda, Y. Ozeki
    • Organizer
      OPJ2016, 2aA6
    • Place of Presentation
      筑波大学東京キャンパス
    • Year and Date
      2016-11-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] パルスレーザーを駆使して細胞を染めずに見る2016

    • Author(s)
      小関泰之
    • Organizer
      第12回UUOサロン
    • Place of Presentation
      板橋区立グリーンホール
    • Year and Date
      2016-10-21
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン散乱を用いた無染色生体顕微法とその応用2016

    • Author(s)
      小関泰之
    • Organizer
      光産業技術振興協会 フォトニックデバイス・応用技術研究会 第3回研究会
    • Place of Presentation
      機械振興会館
    • Year and Date
      2016-10-12
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高速誘導ラマン顕微鏡とその微細藻類の代謝物解析への応用2016

    • Author(s)
      小関泰之、脇坂佳史、鈴木祐太、合田圭介
    • Organizer
      第141回微小光学研究会 -メディカル・バイオフォトニクスに革新をもたらす微小光学-
    • Place of Presentation
      早稲田大学
    • Year and Date
      2016-09-29
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] High-speed multicolor chemical imaging with stimulated Raman scattering2016

    • Author(s)
      Y. Ozeki
    • Organizer
      SciX2016, paper 47
    • Place of Presentation
      ミネアポリス(米国)
    • Year and Date
      2016-09-19
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 光パルスを駆使して無染色生体顕微鏡を超高速化する2016

    • Author(s)
      小関泰之
    • Organizer
      第77回応用物理学会秋季学術講演会シンポジウム「フォトニクスの将来を担う研究者」14p-A41-7
    • Place of Presentation
      新潟
    • Year and Date
      2016-09-14
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] High-speed stimulated Raman scattering microscopy for single-cell analysis of metabolites in live Euglena gracilis2016

    • Author(s)
      Y. Suzuki, Y. Wakisaka, O. Iwata, A. Nakashima, K. Suzuki, T. Ito, M. Hirose, R. Domon, M. Sugawara, N. Tsumura, H. Watarai, T. Shimobaba, K. Goda, and Y. Ozeki
    • Organizer
      第77回応用物理学会秋季学術講演会, 14p-C42-17
    • Place of Presentation
      新潟
    • Year and Date
      2016-09-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 誘導ラマン顕微鏡による高速・無標識生体イメージング2016

    • Author(s)
      小関泰之
    • Organizer
      薄膜・表面物理セミナー
    • Place of Presentation
      早稲田大学
    • Year and Date
      2016-07-29
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン顕微鏡による無標識イメージングの現状と展開2016

    • Author(s)
      小関泰之
    • Organizer
      レーザ顕微鏡研究会
    • Place of Presentation
      理化学研究所
    • Year and Date
      2016-07-07
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン散乱による生体の高速・無標識イメージング2016

    • Author(s)
      小関泰之
    • Organizer
      第32回日本DDS学会学術集会、シンポジウムS5-3
    • Place of Presentation
      グランパス静岡
    • Year and Date
      2016-07-01
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン散乱顕微鏡による高速無標識イメージング2016

    • Author(s)
      小関泰之
    • Organizer
      第41回光学シンポジウム、講演番号17
    • Place of Presentation
      東京大学駒場第2キャンパス
    • Year and Date
      2016-06-24
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] A wavelength-tunable, polarization-maintaining picosecond figure-nine fiber laser2016

    • Author(s)
      Y. Ozeki and T. Fukazu
    • Organizer
      CLEO:2016, JTu5A.119
    • Place of Presentation
      サンノゼ(米国)
    • Year and Date
      2016-06-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A wavelength-tunable, polarization-maintaining picosecond figure-nine fiber laser2016

    • Author(s)
      Y. Ozeki and T. Fukazu
    • Organizer
      CLEO:2016, JTu5A.119
    • Place of Presentation
      San Jose (U.S.A.)
    • Year and Date
      2016-06-07
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 誘導ラマン散乱による高速分子振動イメージングとその応用2016

    • Author(s)
      小関泰之
    • Organizer
      第55回生体医工学会大会、3OS2-1-2
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2016-04-28
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Stimulated Raman scattering microscopy: Development of imaging system and pulsed lasers2016

    • Author(s)
      Y. Ozeki
    • Organizer
      FOM2016
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-03-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 利得スイッチング駆動半導体レーザを用いた誘導ラマン顕微鏡による生細胞イメージング2016

    • Author(s)
      徳永 京也、房 宜澂、横山 弘之、小関 泰之
    • Organizer
      応用物理学会春季講演会、21p-S422-9
    • Place of Presentation
      東京工業大学(目黒区)
    • Year and Date
      2016-03-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] Functional laser sources for multicolor, stain-free biomedical imaging with SRS microscopy2016

    • Author(s)
      Y. Ozeki
    • Organizer
      ODF2016, Weingarten, Germany, Mar. 1, 2016.
    • Place of Presentation
      Weingarten (Germany)
    • Year and Date
      2016-03-01
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Synchronized and timing-stabilized pulse generation from a gain-switched laser diode for stimulated Raman scattering microscopy2016

    • Author(s)
      K. Tokunaga, Yi-Cheng Fang, H. Yokoyama, and Y. Ozeki
    • Organizer
      Photonics West, BiOS, paper 9712-20
    • Place of Presentation
      San Francisco (U.S.A.)
    • Year and Date
      2016-02-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Label-free chemical imaging of live euglena gracilis by high-speed stimulated Raman scattering spectral microscopy2016

    • Author(s)
      Y. Wakisaka, Y. Suzuki, K. Tokunaga, M. Hirose, R. Domon, R. Akaho, M. Kuroshima, N. Tsumura, T. Shimobaba, O. Iwata, K. Suzuki, A. Nakashima, Keisuke Goda, and Yasuyuki Ozeki
    • Organizer
      Photonics West, BiOS, paper 9720-16
    • Place of Presentation
      San Francisco (U.S.A.)
    • Year and Date
      2016-02-13
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 誘導ラマン分光イメージングの進展2015

    • Author(s)
      小関泰之
    • Organizer
      日本分光学会関西支部シンポジウム「最近の分光学の進歩に関する講演会-顕微と分光-」
    • Place of Presentation
      大阪産業大学梅田サテライトキャンパス(大阪市北区)
    • Year and Date
      2015-11-20
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン顕微鏡応用に向けた利得スイッチングLDパルスのタイミング安定化2015

    • Author(s)
      徳永 京也、房 宜澂、草間裕太、横山弘之、小関泰之
    • Organizer
      Optics and Photonics Japan (OPJ2015), 28aC4
    • Place of Presentation
      筑波大学東京キャンパス(東京都文京区)
    • Year and Date
      2015-10-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] Stimulated Raman multispectral imaging with two-color picosecond laser pulses from a gain-switched laser diode and a Ti:sapphire laser2015

    • Author(s)
      Y. Ozeki, K. Tokunaga, Y. -C. Fang, Y. Kusama, and H. Yokoyama
    • Organizer
      Biophotonics Japan, paper 9792-2
    • Place of Presentation
      筑波大学東京キャンパス(東京都文京区)
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 1.06-μm 帯利得スイッチング駆動DFB-LDとチタンサファイアレーザーを用いた誘導ラマン分光イメージング2015

    • Author(s)
      徳永 京也、房 宜澂、草間 裕太、横山 弘之、小関 泰之
    • Organizer
      第76回応用物理学会秋季学術講演会、14p-2N-1
    • Place of Presentation
      名古屋国際会議場(名古屋市熱田区)
    • Year and Date
      2015-09-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Experimental investigation of timing jitter of 1.06-um gain switched laser diode for stimulated Raman scattering microscopy2015

    • Author(s)
      K. Tokunaga, Y. -C. Fang, Y. Kusama, H. Yokoyama, and Y. Ozeki
    • Organizer
      CLEO-PR 2015, 27H2-3
    • Place of Presentation
      Busan (Korea)
    • Year and Date
      2015-08-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Two-color picosecond laser sources for stimulated Raman spectral microscopy2015

    • Author(s)
      Y. Ozeki
    • Organizer
      Topical Problems of Biophotonics, Novel Laser Applications in Biomedicine
    • Place of Presentation
      Nizhny Novgolod (Russia)
    • Year and Date
      2015-07-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Stimulated Raman scattering microscopy for high-speed label-free imaging2015

    • Author(s)
      Y. Ozeki
    • Organizer
      Optical Society of Korea Summer Annual Meeting, OSK-OSJ Joint Symposium on Biophotonics, Gyeongju
    • Place of Presentation
      Gyeongju (Korea)
    • Year and Date
      2015-07-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 光パルスとラマン効果で生体を見る2015

    • Author(s)
      小関泰之
    • Organizer
      先端光科学若手研究会
    • Place of Presentation
      早稲田大学(東京都新宿区)
    • Year and Date
      2015-06-14
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Fast Wavelength-Tunable Picosecond Pulses from Mode-Locked Er Fiber Laser using an Intracavity Filter with Repetition Rate Compensator2015

    • Author(s)
      Y. Ozeki and D. Tashiro
    • Organizer
      CLEO:2015, STh1L.3
    • Place of Presentation
      San Jose (U.S.A.)
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Stimulated Raman scattering microscopy for label-free imaging and spectroscopy2015

    • Author(s)
      Y. Ozeki
    • Organizer
      The 4th Advanced Lasers and Photon Sources, ALPS11-1
    • Place of Presentation
      パシフィコ横浜(横浜市西区)
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 1.06um帯利得スイッチング駆動DFB-LD光パルスのジッタ低減の検討2015

    • Author(s)
      徳永 京也、房 宜澂、草間 裕太、横山 弘之、小関 泰之
    • Organizer
      第62回応用物理学会春季学術講演会、12a-A15-10
    • Place of Presentation
      東海大学、神奈川県
    • Year and Date
      2015-03-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] 共振器内フィルタを有する高速波長可変ピコ秒モード同期ファイバレーザ2015

    • Author(s)
      田代 大悟、小関 泰之
    • Organizer
      第62回応用物理学会春季学術講演会、12a-A15-9
    • Place of Presentation
      東海大学、神奈川県
    • Year and Date
      2015-03-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Fast spectrum extraction from SRS spectral images by independent component analysis with image compression and post sampling2015

    • Author(s)
      Y. Ozeki
    • Organizer
      SPIE Photonics West, 9329-62
    • Place of Presentation
      San Francisco, U.S.A.
    • Year and Date
      2015-02-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] ファイバーレーザー光を用いたリアルタイム誘導ラマン散乱顕微鏡の開発2015

    • Author(s)
      小関泰之、岸達也、能勢啓輔、伊東一良
    • Organizer
      レーザー学会学術講演会第35回年次大会、12a-I-6
    • Place of Presentation
      東海大学高輪キャンパス、東京都
    • Year and Date
      2015-01-12
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Recent advances on stimulated Raman scattering spectral microscopy2014

    • Author(s)
      Y. Ozeki
    • Organizer
      Biomedical Molecular Imaging (BMI2014)
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2014-11-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Real-time multicolor stain-free imaging of tissue with stimulated Raman scattering microscopy2014

    • Author(s)
      Y. Ozeki
    • Organizer
      SPIE Photonics Asia
    • Place of Presentation
      Beijing, China
    • Year and Date
      2014-10-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] What could be visualized with stimulated Raman scattering?2014

    • Author(s)
      Y. Ozeki
    • Organizer
      The 52nd Ann. Meeting of the Biophys. Soc. Jpn., 3SDA-7
    • Place of Presentation
      札幌コンベンションセンター、北海道
    • Year and Date
      2014-09-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Group delay compensation of spectrally-filtered picosecond pulses for stimulated Raman microscopy2014

    • Author(s)
      Y. Ozeki, K. Tokunaga, ald K. Nose
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO2014), JTh2.30
    • Place of Presentation
      San Jose, U.S.A.
    • Year and Date
      2014-06-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Multicolor, stain-free imaging of tissue with stimulated Raman scattering2014

    • Author(s)
      Y. Ozeki
    • Organizer
      Biomedical Imaging and Sensing Conference (BISC2014), BISC2-1
    • Place of Presentation
      パシフィコ横浜、神奈川県
    • Year and Date
      2014-04-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Group Delay Compensation of Spectrally-Filtered Picosecond Pulses for Stimulated Raman Microscopy

    • Author(s)
      Y. Ozeki, K. Nose, K. Tokunaga
    • Organizer
      CLEO: 2014
    • Place of Presentation
      米国、サンフランシスコ
    • Related Report
      2013 Annual Research Report
  • [Remarks] Ozeki group

    • URL

      https://sites.google.com/site/ozekibp/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 微生物の個性を測る高速分子イメージング法を開発

    • URL

      http://www.t.u-tokyo.ac.jp/foe/press/setnws_20160802105732051679502063.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] Ozeki Group

    • URL

      https://sites.google.com/site/ozekibp/

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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