| Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2015: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2014: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2013: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
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| Outline of Final Research Achievements |
We have developed a series of nano-sized temperature-responsive polymer-protein conjugates that separate and enrich analytes from solution and enable detection. Because smart conjugates bind analytes in solution prior to separation, conjugate-analytes binding avoids steric and mass transport limitations associated with surface-based techniques. Thus, the “smart” polymer-based diagnostic systems could enrich dilute salivary samples, overcoming the problem of low power supply in the developing world while retaining the advantages of a rapid and reversible capture and concentration abilities.
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