• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Contribution of reflex cardiovascular control to exercising muscle blood flow and exercise performance

Research Project

Project/Area Number 25702042
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Sports science
Research InstitutionMeiji University

Principal Investigator

Ichinose Masashi  明治大学, 経営学部, 准教授 (10551476)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Keywords循環調節 / 末梢反射 / 活動筋血流量 / 動脈血圧 / 運動パフォーマンス / 運動生理学 / 血圧 / 末梢血流量
Outline of Final Research Achievements

In the present study, 1) we developed experimental model that noninvasively increases exercising muscle blood flow during dynamic exercise in humans. In addition, 2) with this model we found that increase in muscle blood flow attenuates cardiovascular responses during dynamic exercise at higher than moderate intensity and improves endurance performance. Moreover, 3) our results indicate that inhibition of the muscle metaboreflex would be involved in the attenuation of the cardiovascular responses elicited by increases in exercising muscle blood flow. The results of this study contribute to elucidate the mechanisms of cardiovascular regulations during exercise, and will be an important scientific knowledge when considering safety of exercise and effectiveness of exercise training to improve exercise performance.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (23 results)

All 2015 2014 2013

All Journal Article (8 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 8 results,  Acknowledgement Compliant: 3 results,  Open Access: 1 results) Presentation (15 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results)

  • [Journal Article] Increasing blood flow to exercising muscle attenuates systemic cardiovascular responses during dynamic exercise in humans.2015

    • Author(s)
      Ichinose M, Ichinose-Kuwahara T, Kondo N, Nishiyasu T.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol.

      Volume: 309 Issue: 10 Pages: R1234-R1242

    • DOI

      10.1152/ajpregu.00063.2015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Cardiovascular responses to forearm muscle metaboreflex activation during hypercapnia in humans.2015

    • Author(s)
      Delliaux S, Ichinose M, Watanabe K, Fujii N, Nishiyasu T.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol.

      Volume: 309 Issue: 1 Pages: R43-R50

    • DOI

      10.1152/ajpregu.00402.2014

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Modulation of muscle metaboreceptor activation upon sweating and cutaneous vascular responses to rising core temperature in humans.2015

    • Author(s)
      Amano T, Ichinose M, Inoue Y, Nishiyasu T, Koga S, Kondo N.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol.

      Volume: 308 Issue: 12 Pages: 990-997

    • DOI

      10.1152/ajpregu.00005.2015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Stimulation of the cardiopulmonary baroreflex enhances ventricular contractility in awake dogs: a mathematical analysis study.2014

    • Author(s)
      Sala-Mercado JA, Moslehpour M, Hammond RL, Ichinose M, Chen X, Evan S, O'Leary DS, Mukkamala R3
    • Journal Title

      American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

      Volume: 307 Issue: 4 Pages: 455-464

    • DOI

      10.1152/ajpregu.00510.2013

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sweating response to passive stretch of the calf muscle during activation of forearm muscle metaboreceptors in heated humans.2014

    • Author(s)
      Amano T, Ichinose M, Nishiyasu T, Inoue Y, Koga S, Miwa M, Kondo N.
    • Journal Title

      American Journal of Physiology Regulatory, Integrative and Comparative Physiology

      Volume: In press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in cardiac and vascular components of the pressor response to isometric handgrip exercise in humans2014

    • Author(s)
      Kazuhito Watanabe, Masashi Ichinose, Rei Tahara and Takeshi Nishiyasu
    • Journal Title

      American Journal of Physiology-Heart and Circulatory Physiology

      Volume: VOL. 306 Issue: 2 Pages: 251-260

    • DOI

      10.1152/ajpheart.00699.2013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blood pressure regulation II: what happens when one system must serve two masters--oxygen delivery and pressure regulation?2014

    • Author(s)
      Ichinose M, Maeda S, Kondo N, Nishiyasu T.
    • Journal Title

      European Journal of Applied Physiology

      Volume: 114(3) Issue: 3 Pages: 451-465

    • DOI

      10.1007/s00421-013-2691-y

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Muscle metaboreflex activation speeds the recovery of arterial blood pressure following acute hypotension in humans2013

    • Author(s)
      Masashi Ichinose, Kazuhito Watanabe、 Naoto Fujii, Narihiko Kondo and Takeshi Nishiyasu
    • Journal Title

      American Journal of Physiology-Heart and Circulatory Physiology

      Volume: (In press) Issue: 11 Pages: 1568-1575

    • DOI

      10.1152/ajpheart.00833.2012

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 頸動脈圧受容器反射が筋代謝受容器反射の昇圧閾値に及ぼす影響2015

    • Author(s)
      一之瀬真志,一之瀬智子,渡邊和仁,西保 岳
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県和歌山市
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] ハンドグリップ運動時における血圧上昇要因の個人差:運動様式の違いに着目して2015

    • Author(s)
      渡邊和仁,一之瀬真志,辻 文,前田清司,西保 岳
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県和歌山市
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] 前腕部における筋代謝受容器活動が自転車運動時の熱放散反応に及ぼす影響2015

    • Author(s)
      天野達郎,一之瀬真志,井上芳光,西保 岳,近藤徳彦
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県和歌山市
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Pressor threshold of muscle metaboreflex is modulated during unloading of carotid baroreceptors in humans.2015

    • Author(s)
      Ichinose M, Ichinose-Kuwahara T, Watanabe K, Nishiyasu T.
    • Organizer
      16th International Conference on Environmental Ergonomics
    • Place of Presentation
      Portsmouth, UK.
    • Year and Date
      2015-06-29
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Carotid Baroreflex Modifies Pressor Threshold of Muscle Metaboreflex in Humans.2015

    • Author(s)
      Ichinose M, Ichinose-Kuwahara T, Watanabe K, Nishiyasu T.
    • Organizer
      62nd American College of Sports Medicine annual meeting
    • Place of Presentation
      San Diego, California, USA.
    • Year and Date
      2015-05-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Time-Dependent Changes in Individual Differences in Components of the Pressor Responses to Isometric Handgrip Exercise.2015

    • Author(s)
      Watanabe K, Ichinose M, Tsuji B, Nishiyasu T.
    • Organizer
      62nd American College of Sports Medicine Annual Meeting
    • Place of Presentation
      San Diego, California, USA.
    • Year and Date
      2015-05-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural Cardiovascular Control during Exercise: Contribution of Exercising Muscle Blood Flow to Systemic Blood Pressure Regulations2015

    • Author(s)
      Ichinose M
    • Organizer
      International Symposium on Human Adaptation to Environment and Whole-body Coordination
    • Place of Presentation
      神戸大学(兵庫県・神戸市)
    • Year and Date
      2015-03-14 – 2015-03-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 動的運動時における活動肢血流量の増加が持久性運動能力と循環および呼吸反応に及ぼす影響2014

    • Author(s)
      一之瀬真志,一之瀬智子,西保 岳
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎県・長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] 活動筋血流量と血圧調節の関係性‐神経性循環調節の役割‐2014

    • Author(s)
      一之瀬真志
    • Organizer
      第22回日本運動生理学会大会
    • Place of Presentation
      川崎医療福祉大学(岡山県・倉敷市)
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 静的ハンドグリップ運動時における血圧上昇要因の個人差:運動中の経時的変化に着目して2014

    • Author(s)
      渡辺和仁,一之瀬真志,西保 岳
    • Organizer
      第22回日本運動生理学会大会
    • Place of Presentation
      川崎医療福祉大学(岡山県・倉敷市)
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Increase in Exercising Leg Blood Flow Improves Endurance Performance during Dynamic Plantarflexion Exercise2014

    • Author(s)
      Ichinose M, Ichinose T, Nishiyasu T
    • Organizer
      61st American College of Sports Medicine Annual Meeting
    • Place of Presentation
      フロリダ州オーランド(アメリカ合衆国)
    • Year and Date
      2014-05-27 – 2014-05-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] Natural Killer Cells Response To The Muscular Metaboreflex2014

    • Author(s)
      Suzui M, Ichinose M, Takeda K, Yagita H, Shek PN, Shephard RJ, Okumura K
    • Organizer
      61st American College of Sports Medicine Annual Meeting
    • Place of Presentation
      フロリダ州オーランド(アメリカ合衆国)
    • Year and Date
      2014-05-27 – 2014-05-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] Increase in Exercising Leg Blood Flow Attenuates Systemic Cardiovascular Responses During Dynamic Planter Flexion Exercise.2013

    • Author(s)
      Ichinose M, Ichinose T, Nishiyasu T
    • Organizer
      60th American college of sports medicine annual meeting
    • Place of Presentation
      Indianapolis, Indiana, USA.
    • Related Report
      2013 Annual Research Report
  • [Presentation] 筋代謝受容器反射が血中免疫細胞動態に及ぼす影響2013

    • Author(s)
      一之瀬真志,鈴井正敏,竹田和由
    • Organizer
      第68回日本体力医学会
    • Place of Presentation
      東京都千代田区
    • Related Report
      2013 Annual Research Report
  • [Presentation] 静的ハンドグリップ運動時における心拍出量および末梢血管抵抗の反応の個人差2013

    • Author(s)
      渡邊和仁,一之瀬真志,田原麗衣,西保 岳
    • Organizer
      第68回日本体力医学会
    • Place of Presentation
      東京都千代田区
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-21   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi