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Investigation of electrical interactions between biomolecules and nanomaterials

Research Project

Project/Area Number 25706012
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Nano/Microsystems
Research InstitutionTokyo Institute of Technology

Principal Investigator

Hayamizu Yuhei  東京工業大学, 理工学研究科, 准教授 (80443216)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2013: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Keywordsナノシート / ペプチド / 自己組織化 / グラフェン / 二硫化モリブデン / ナノマイクロバイオシステム / バイオナノ界面
Outline of Final Research Achievements

The aim of this research was to understand the electrical interactions between biomolecules and 2-dimensional nanosheets by using peptides and layered materials such as grapehene and MoS2. First, we have focused on understanding the fundamentals of peptide self-assembly on nanomaterials. Especially, the self-assembly of graphite binding peptides has been investigated comprehensively. Then, the electrical interactions between peptides and nanosheets have been investigated using MoS2 FETs. The observations indicate that chemical doping by peptides on 2D nanosheets plays a significant role for the modification of the electrical and optical properties of 2D nanosheets.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (36 results)

All 2016 2015 2014 2013 Other

All Journal Article (6 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 6 results,  Acknowledgement Compliant: 2 results) Presentation (27 results) (of which Int'l Joint Research: 2 results,  Invited: 7 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Laser-induced electrochemical thinning of MoS22016

    • Author(s)
      K. Sunamura , T. R. Page , K. Yoshida , T. Yano and Y. Hayamizu
    • Journal Title

      J. Mater. Chem. C

      Volume: 4 Issue: 15 Pages: 3268-3273

    • DOI

      10.1039/c5tc04409j

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Probing edge-activated resonant Raman scattering from mechanically exfoliated 2D MoO3 nanolayers2015

    • Author(s)
      Yano, T., Yoshida, K., Hayamizu, Y., Hayashi, T., Ohuchi, F., Hara, M.
    • Journal Title

      2D Materials

      Volume: 2 Issue: 3 Pages: 035004-035004

    • DOI

      10.1088/2053-1583/2/3/035004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Spectroscopic Study of Firefly Oxyluciferin in Enzymatic Environment on the Basis of Stability Monitoring2014

    • Author(s)
      Yu Wang, Yuhei Hayamizu, Hidefumi Akiyama
    • Journal Title

      J. Phys. Chem

      Volume: B 118 Issue: 8 Pages: 2070-2076

    • DOI

      10.1021/jp411476p

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective Detection of Target Proteins by Peptide‐Enabled Graphene Biosensor2014

    • Author(s)
      D Khatayevich, T Page, C Gresswell, Y Hayamizu, W Grady, M Sarikaya
    • Journal Title

      Small

      Volume: 10 Issue: 8 Pages: 1505-1513

    • DOI

      10.1002/smll.201302188

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Selective Detection of Target Proteins by Peptide-Enabled Graphene Biosensor2014

    • Author(s)
      Dmitriy Khatayevich, Tamon Page, Carolyn Gresswell, Yuhei Hayamizu, William Grady and Mehmet Sarikaya
    • Journal Title

      Small

      Volume: 10 Issue: 8 Pages: 1504-1504

    • DOI

      10.1002/smll.201470047

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intrinsic radiative lifetime derived via absorption cross section of one-dimensional excitons2013

    • Author(s)
      Shaoqiang Chen, Masahiro Yoshita, Akira Ishikawa, Toshimitsu Mochizuki, Shun Maruyama, Hidefumi Akiyama, Yuhei Hayamizu, Loren N. Pfeiffer, and Ken W. West
    • Journal Title

      Scientific Reports

      Volume: 3 Issue: 1 Pages: 1941-1941

    • DOI

      10.1038/srep01941

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Crystallographic Orientation of Self-Assembled Peptides on CVD MoS2 Single Crystal2016

    • Author(s)
      Linhao Sun, Kouhei Sakuma, Shohei Tsuchiya, Hiroto Fukata, Mehmet Sarikaya, Yuhei Hayamizu
    • Organizer
      Materials Research Society spring meeting 2016
    • Place of Presentation
      Phenix, AZ, USA
    • Year and Date
      2016-03-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] In Situ Observation of Fluorescent-Tagged Peptides Diffusing on Boron Nitride by Single Molecule Tracking2016

    • Author(s)
      Peiying Li, Koji Noda, Shuzo Hirata, Martin Vacha, Mehmet Sarikaya, Yuhei Hayamizu
    • Organizer
      Materials Research Society spring meeting 2016
    • Place of Presentation
      Phenix, AZ, USA
    • Year and Date
      2016-03-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 2 次元材料表面において自己組織化するβシート型機能性ペプチドの開発2015

    • Author(s)
      佐久間洸平, 深田拓人, 早水裕平
    • Organizer
      表面科学学術講演会
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2015-12-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 電気化学的なバイアスによるペプチドの自己組織化挙動の制御2015

    • Author(s)
      関 貴一, Page Tamon, 早水 裕平
    • Organizer
      表面科学学術講演会
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2015-12-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effect of Temperature on Self-Assembled Peptide at Water-Graphite/MoS2 Interface2015

    • Author(s)
      Linhao Sun, Morio Isoda, Mehmet Sarikaya, Yuhei Hayamizu
    • Organizer
      Materials Research Society fall meeting 2015
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2015-11-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 層状物質上におけるグラファイト結合ペプチドの膜安定性と非特異吸着防止効果の評価2015

    • Author(s)
      増島 弘顕, 大西 知子, 早水 裕平
    • Organizer
      生物工学会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2015-10-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 乳酸菌と親和性を持つグラフェン結合ペプチドの評価2015

    • Author(s)
      大西 知子, 増島 弘顕, 田中 祐圭, 大河内 美奈, 早水 裕平
    • Organizer
      生物工学会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2015-10-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 2次元ナノ材料上で規則正しく自己組織化するペプチド2015

    • Author(s)
      早水裕平
    • Organizer
      第64回高分子討論会
    • Place of Presentation
      東北大学 宮城県仙台市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 界面非平衡系におけるグラファイト吸着ペプチドのモルフォロジー変化2015

    • Author(s)
      土屋 匠平, 磯田 盛夫, Mehmet Sarikaya, 早水 裕平
    • Organizer
      応用物理学会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 電気化学的なバイアスによるペプチドの自己組織化挙動の制御2015

    • Author(s)
      関 貴一, Page Tamon, 早水 裕平
    • Organizer
      応用物理学会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 蛍光一分子追跡法を用いた窒化ホウ素上を拡散するペプチドのその場観測2015

    • Author(s)
      李佩瑩,野田紘志,平田修造,Martin Vacha,Mehmet Sarikaya, 早水裕平
    • Organizer
      応用物理学会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Engineering of Bio-Nano Interfaces on 2D Nanomaterials by Self-Assembled Peptides2015

    • Author(s)
      Yuhei Hayamizu
    • Organizer
      12th International Conference Advanced Carbon Nanostructures (ACNS2015)
    • Place of Presentation
      Saint-Petersburg, Russia
    • Year and Date
      2015-07-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Engineering of bio-nano interfaces on 2D nanomaterials by self-assembled peptides2015

    • Author(s)
      Yuhei Hayamizu
    • Organizer
      International Symposium on Intercalation Compounds (ISIC18)
    • Place of Presentation
      Strasbourg, France
    • Year and Date
      2015-06-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Engineering of Bio-Nano Interfaces with Self-Assembled Peptides2014

    • Author(s)
      Yuhei Hayamizu
    • Organizer
      Pacsurf2014
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2014-12-09
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 蛍光一分子追跡法によるペプチド自己組織化のその場観測2014

    • Author(s)
      Li Peying and Yuhei Hayamizu
    • Organizer
      物性研短期研究会
    • Place of Presentation
      東京大学物性研究所、柏市
    • Year and Date
      2014-12-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Self-Organized Peptides on 2-Dimensional Nanomaterials2014

    • Author(s)
      Yuhei Hayamizu, Christopher R So, Sefa Dag, Tamon R Page, David Starkebaum, and Mehmet Sarikaya
    • Organizer
      2014 MRS fall meeting
    • Place of Presentation
      Boston, Massachusetts, USA
    • Year and Date
      2014-12-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] 二次元材料上におけるペプチド自己集合の温度依存性2014

    • Author(s)
      磯田盛夫、深田拓人、早水裕平
    • Organizer
      第34回表面科学学術講演会
    • Place of Presentation
      松江・島根県立産業交流会館 島根県
    • Year and Date
      2014-11-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] 二次元材料上において安定な単分子膜を形成する新規架橋性ペプチドの開発2014

    • Author(s)
      深田拓人、早水裕平
    • Organizer
      第34回表面科学学術講演会
    • Place of Presentation
      松江・島根県立産業交流会館 島根県
    • Year and Date
      2014-11-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] 蛍光修飾した自己組織化ペプチドのその場観察2014

    • Author(s)
      李佩瑩1,野田紘志1,平田修造1,Martin Vacha1,Mehmet Sarikaya2,早水裕平1
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学キャンパス 札幌市
    • Year and Date
      2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] ペプチド修飾されたMoS2FETの液中電気特性評価2014

    • Author(s)
      砂村海斗1,Tamon Page2,Mehmet Sarikaya2,早水裕平1
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学キャンパス 札幌市
    • Year and Date
      2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] The crystallographic orientation of self-assembled peptides on CVD-grown MoS2 single crystal2014

    • Author(s)
      Linhao Sun1,Fukata Hiroto1,Peiying Li1,Mehmet Sarikaya2,Yuhei Hayamizu1
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学キャンパス 札幌市
    • Year and Date
      2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] グラフェンにおける化学ドーピングと有機分子の仕事関数との相関2014

    • Author(s)
      増島弘顕,森健彦,早水裕平
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学キャンパス 札幌市
    • Year and Date
      2014-09-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] 機能性ペプチドとナノマテリアルを用いたバイオ・ナノ界面の制御

    • Author(s)
      早水 裕平
    • Organizer
      関東高分子若手研究会サマーキャンプ
    • Place of Presentation
      千葉県館山市 東京農工大学合宿宿泊施設 館山荘
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Modification of photoluminescence in a single-layer MoS2 by self-assembled peptides

    • Author(s)
      Tamon Page, Yuhei Hayamizu and Mehmet Sarikaya
    • Organizer
      5th International conference on Recent Progress in Graphene Research
    • Place of Presentation
      Tokyo Institute of Technology, Ookayama, Tokyo
    • Related Report
      2013 Annual Research Report
  • [Presentation] Modification of graphene conductivity by self-assembled peptides

    • Author(s)
      Yuhei Hayamizu and Mehmet Sarikaya
    • Organizer
      5th International conference on Recent Progress in Graphene Research
    • Place of Presentation
      Tokyo Institute of Technology, Ookayama, Tokyo
    • Related Report
      2013 Annual Research Report
  • [Presentation] "自己組織化ペプチドによる 2次元ナノ材料の顕微分光"

    • Author(s)
      早水 裕平
    • Organizer
      第78回表面科学研究会 ナノスケールの振動分光の最前線
    • Place of Presentation
      東京工業大学 大岡山 東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 機能性ペプチドとナノマテリアルを用いたバイオ・ナノ界面の制御

    • Author(s)
      早水 裕平
    • Organizer
      "物性研究所 平成25年度後期短期研究会 「エネルギーと新材料の物性・物質科学」"
    • Place of Presentation
      東京大学 物性研究所
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] グラファイト表面におけるペプチド自己組織化単分子膜の熱力学的評価2015

    • Author(s)
      磯田盛夫 早水裕平
    • Total Pages
      6
    • Publisher
      表面科学、日本表面科学会
    • Related Report
      2015 Annual Research Report
  • [Remarks] 東京工業大学 早水研究室

    • URL

      http://www.op.titech.ac.jp/lab/hayamizu/

    • Related Report
      2013 Annual Research Report
  • [Patent(Industrial Property Rights)] 自己組織化ペプチド及びその利用2015

    • Inventor(s)
      早水裕平 深田拓人
    • Industrial Property Rights Holder
      早水裕平 深田拓人
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-081761
    • Filing Date
      2015-04-13
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2013-05-21   Modified: 2019-07-29  

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