| Budget Amount *help |
¥26,390,000 (Direct Cost: ¥20,300,000、Indirect Cost: ¥6,090,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
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| Outline of Final Research Achievements |
The Pd(0)-mediated regioselective C-F bond cleavage of perfluoroalkene has been developed by adopting the proper choice of the Lewis acid additive. Thus, the addition of tris(pentafluorophenyl)borane to eta2-hexafluoro propylene Pd(0) complex allowed the sp3-C-F bond cleavage in a selective manner to yield a cationic perfluoroallyl complex. In contrast, the use of BF3-etherate resulted in the quantitative sp2-C-F bond cleavage to yield a perfluoropropenyl complex.
We found that the allylic C-F bond cleavage would be the kinetically dominant process in our system, and that both steric hindrance and nucleophilicity of the counter anion or the resultant conjugated base would be the key to determine the structure of C－F bond cleavage product.
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