| Budget Amount *help |
¥26,780,000 (Direct Cost: ¥20,600,000、Indirect Cost: ¥6,180,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
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| Outline of Final Research Achievements |
As a method to introduce a functional group at the reaction initiation site in the palladium-catalyzed chain-walking cycloisomerization of 1,n-dienes, we developed a cyclization/hydrosilylation of 1,n-dienes via chain-walking. In the presence of palladium catalysts, the reaction of various 1,n-dienes with hydrosilanes proceeded to give products formed by five-membered ring formation after the introduction of a silyl group, followed by chain walking. We also investigated on how to control the position of the alkene formed after the chain-walking process and found that the use of siloxy groups to form silyl enol ethers was effective for settling the position of the alkene after chain walking.
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