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Measurement of local ion levels near membranes with fluorescent ion sensors

Research Project

Project/Area Number 25708023
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Analytical chemistry
Research InstitutionThe University of Tokyo

Principal Investigator

UCHIYAMA SEIICHI  東京大学, 薬学研究科(研究院), 助教 (10401225)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
Fiscal Year 2015: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2014: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2013: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Keywords分析試薬 / 蛍光 / センサー / 膜 / イオン / 国際研究者交流 / イギリス
Outline of Final Research Achievements

We synthesized 15 kinds of fluorescent proton sensors and 5 kinds of fluorescent sodium ion sensors having a benzofurazan or an anthracene structure as a fluorophore. Using these novel fluorescent sensors, we measured local ion levels near micelle surfaces. As a result, it was clarified that protons and sodium ions are concentrated near the head groups because of electric interactions in anionic micelles. On the other hand, protons are diluted near the head groups of neutral and cationic micelles due to electric and/or dielectric effects.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (8 results)

All 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Int'l Joint Research: 2 results) Book (2 results)

  • [Int'l Joint Research] Queen's University(英国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Measurement of local sodium ion levels near micelle surfaces with fluorescent photoinduced-electron-transfer sensors2016

    • Author(s)
      Seiichi Uchiyama, Eiko Fukatsu, Gareth D. McClean, A. Prasanna de Silva
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 55 Issue: 2 Pages: 768-771

    • DOI

      10.1002/anie.201509096

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Measurement of local sodium ion levels near micelle surfaces with fluorescent photoinduced-electron-transfer sensors2016

    • Author(s)
      Seiichi Uchiyama
    • Organizer
      5th International conference on molecular sensors and molecular logic gates
    • Place of Presentation
      Bath (University of Bath, UK)
    • Year and Date
      2016-07-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Measurement of local sodium ion levels near micelle surfaces with fluorescent photoinduced-electron-transfer sensors2016

    • Author(s)
      Seiichi Uchiyama
    • Organizer
      26th IUPAC International Symposium on Photochemistry
    • Place of Presentation
      大阪(大阪市中央公会堂)
    • Year and Date
      2016-04-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光誘起電子移動の制御を利用した蛍光センサーによるミセル表面付近のナトリウムイオン濃度測定2015

    • Author(s)
      深津英子
    • Organizer
      第75回分析化学討論会
    • Place of Presentation
      甲府(山梨大学)
    • Year and Date
      2015-05-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] 光誘起電子移動の制御を利用した蛍光センサーによるミセル表面付近のナトリウムイオン濃度測定2015

    • Author(s)
      深津英子、内山聖一、Gareth D. McClean、A. P. de Silva
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      千葉
    • Year and Date
      2015-03-26
    • Related Report
      2014 Annual Research Report
  • [Book] 分子論理ゲート-情報処理のできる機能性分子2014

    • Author(s)
      A. P. de Silva, 内山 聖一
    • Total Pages
      219
    • Publisher
      講談社
    • Related Report
      2014 Annual Research Report
  • [Book] 分子論理ゲート(予定)2014

    • Author(s)
      内山聖一、A. Prasanna de Silva
    • Total Pages
      300
    • Publisher
      講談社サイエンティフィク
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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