Dosimetry of secondary particles generated in therapeutic radiation fields

• Project/Area Number: 25713047
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Radiation science
• Research Institution: National Institute of Radiological Sciences
• Principal Investigator: Kodaira Satoshi 国立研究開発法人放射線医学総合研究所, 研究基盤センター, 主任研究員 (00434324)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000); Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2013: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
• Keywords: 医療被ばく / 放射線治療 / 二次粒子 / CR-39

Outline of Final Research Achievements

We have measured the secondary particles generated by the nuclear interactions with matters in the therapeutic radiation such as X-ray, proton and carbon beams. Especially, we have established the angular correction method for evaluating the dose of secondary particles quantitatively. For example, we found that the proton-induced secondary particles contribute to 20% in dose equivalent for primary protons. The production cross section depends on the nuclear charge of primary ions. The cross section for carbon beam is about 25 times higher than proton beam. On the other hand, the particle fluence giving 1 Gy dose for carbon beam is about 1/25 lower than proton beam. Therefore, in the viewpoint of dosimetry, we confirmed that the dose contribution of secondary particles for carbon beam is about 1/5 - 1/6 lower than proton beam.

Research Products

• [Int'l Joint Research] Oklahoma State University(米国)
• [Int'l Joint Research] Technische University Wien(オーストリア)
• [Int'l Joint Research] Institute of Biomedical Problem(ロシア連邦)
• [Journal Article] On the use of CR-39 PNTD with AFM analysis in measuring proton-induced target fragmentation particles (2015)
  • Author(s): S. Kodaira, T. Konishi, H. Kitamura, M. Kurano, H. Kawashima, Y. Uchihori, T. Nishio, N. Yasuda, K. Ogura, L. Sihver, E.R. Benton
  • Journal Title: Nucl. Instrum. Meth. B Volume: 349 Pages: 163-168
  • DOI: 10.1016/j.nimb.2015.02.052
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Measurement of the secondary neutron dose distribution from the LET spectrum of recoils using the CR-39 plastic nuclear track detector in 10 MV X-ray medical radiation fields (2015)
  • Author(s): T. Fujibuchi, S. Kodaira, F. Sawaguchi, Y. Abe, S. Obara, M. Yamaguchi, H. Kawashima, H. Kitamura, M. Kurano, Y. Uchihori, N. Yasuda, Y. Koguchi, M. Nakajima, N. Kitamura, T. Sato
  • Journal Title: Nucl. Instrum. Meth. B Volume: 349 Pages: 239-245
  • DOI: 10.1016/j.nimb.2015.03.006
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 陽子・ヘリウムを成因とする標的核破砕二次粒子の宇宙放射線線量への寄与 (2016)
  • Author(s): 小平聡, 内堀幸夫, 北村尚, 川嶋元, 蔵野美恵子, 小倉紘一, 安田仲宏, Lembit Sihver, Eric Benton
  • Organizer: 第30回固体飛跡検出器研究会
  • Place of Presentation: 福井大学附属国際原子力工学研究所
  • Year and Date: 2016-03-14
• [Presentation] CR-39と原子核乾板を用いた重イオンの核破砕反応の計測 (2016)
  • Author(s): 四之宮創, 小平聡, 森島邦博, 長谷部信行, 蔵野美恵子, 久下謙一
  • Organizer: 第30回固体飛跡検出器研究会
  • Place of Presentation: 福井大学附属国際原子力工学研究所
  • Year and Date: 2016-03-14
• [Presentation] Dosimetry of therapeutic carbon beam and its fragments with CR-39 plastic nuclear track detectors (2015)
  • Author(s): S Kodaira, N. Matsufuji, T Saito, N. Hasebe, H Kitamura, Y Uchihori, H Kawashima, M. Kurano, O. Ploc, L Sihver
  • Organizer: The 15th International Congress of Radiation Research
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2015-05-25
• [Presentation] Dosimetry of proton-induced target fragments with CR-39 PNTD and AFM (2015)
  • Author(s): S. Kodaira, T.Konishi, Y. Uchihori, H. Kitamura, M. Kurano, H. Kawashima, L. Sihver, Eric Benton
  • Organizer: Space Radiation and Heavy Ions in Therapy Symposium 2015
  • Place of Presentation: あべのハルカス
  • Year and Date: 2015-05-22
• [Presentation] CR-39を用いた自動飛跡追跡法による重イオンの核破砕反応断面積の測定 (2015)
  • Author(s): 花岡慶祐、小平聡、蔵野美恵子、川嶋元、長谷部信行
  • Organizer: 第29回固体飛跡検出器研究会
  • Place of Presentation: 福井大学
  • Year and Date: 2015-03-30 – 2015-03-31
• [Presentation] CR-39とAFMを用いた陽子線からの標的核破砕粒子の線量計測法 (2015)
  • Author(s): 小平聡, 小西輝昭, 北村尚, 内堀幸夫, 川嶋元, 蔵野美恵子, 西尾禎治, 安田仲宏, 小倉紘一, Lembit Sihver, Eric R. Benton
  • Organizer: 第29回固体飛跡検出器研究会
  • Place of Presentation: 福井大学
  • Year and Date: 2015-03-30
• [Presentation] CR-39を用いた炭素線とフラグメント粒子の線量計測 (2014)
  • Author(s): 小平聡, 松藤成弘, 北村尚, 内堀幸夫, 川嶋元, 蔵野美恵子, Ondrej Ploc, Lembit Sihver
  • Organizer: 第28回固体飛跡検出器（応用物理学会放射線分科会共催）
  • Place of Presentation: 神戸大学深江キャンパス
• [Presentation] Dosimetric measurement of secondary particles from therapeutic radiation beams (2014)
  • Author(s): Satoshi Kodaira
  • Organizer: The 2nd Global Chinese Congress of Radiation Research
  • Place of Presentation: Suzhou, China
  • Invited