| Budget Amount *help |
¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2014: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Outline of Final Research Achievements |
We performed microarray and integrated analyses of microRNA-mRNA expression profiles for masseter muscle in rats fed the soft or hard diets. In addition, we identified the miRNAs and mRNAs associated with the angiogenesis and endochondral ossification using Gene Ontology (GO) analysis.
GO analysis predicted interactions between 12 genes and 8 miRNAs, including some angiogenesis factors and ossification genes. In particular, 5 mRNAs associated with angiogenesis and endochondral ossification were identified as potential targets of rno-miR-19b-3p and rno-miR-181c-5p, respectively.
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