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Impact of maternal BMI and dietary intake on health of mother and child.

Research Project

Project/Area Number 25750036
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Research InstitutionYamanashi Gakuin University

Principal Investigator

YACHI Yoko  山梨学院大学, 健康栄養学部, 講師 (30642821)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords若年女性のやせ / 低出生体重児 / 妊産婦の栄養 / BMI / 血糖値 / 妊娠糖尿病
Outline of Final Research Achievements

Birth weight is known to affect not only perinatal health or subsequent growth/development but also morbidity in later life. Especially low birth weight (LBW) is now recognized as an established risk for future metabolic abnormalities, including obesity and diabetes. Although it is well known that hyperglycemia is an important risk factor for macrosomia, whether maternal glucose levels are associated with incident neonatal LBW is unknown. We therefore examined the associations between maternal glycemia within normal glucose tolerance and the risk of LBW infants in Japanese mothers. In addition, we examined the relative contributions of maternal glycemia and BMI to LBW.
In this study, a low 1-h postload glucose level but within normal range and low maternal BMI alone, as well as in combination, were independently associated with an increased risk of incident LBW independent of other known risk factors. Their combination had a greater impact than either value alone.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (32 results)

All 2015 2014 2013

All Journal Article (13 results) (of which Peer Reviewed: 13 results,  Open Access: 2 results,  Acknowledgement Compliant: 4 results) Presentation (18 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] 妊婦の糖代謝2015

    • Author(s)
      谷内洋子、曽根博仁
    • Journal Title

      bios

      Volume: 20 Pages: 3-6

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 妊娠中の母体血糖状態と低出生体重児出産2015

    • Author(s)
      谷内洋子、曽根博仁
    • Journal Title

      糖尿病と妊娠

      Volume: 15

    • NAID

      40020585166

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 日本人女性の妊娠前後の体型および栄養摂取が母児の健康に及ぼす影響の検証2014

    • Author(s)
      谷内 洋子
    • Journal Title

      栄養学雑誌

      Volume: 72 Pages: 47-48

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High Risk of Failing Eradication of Helicobacter Pylori in Patients with Diabetes: A Meta-analysis2014

    • Author(s)
      Horikawa C, Kodama S, Fujihara K, Hirasawa R, Yachi Y, Suzuki A, Hanyu O, Shimano H, Sone H
    • Journal Title

      Diabet Res Clin Prac

      Volume: 106 Issue: 1 Pages: 81-7

    • DOI

      10.1016/j.diabres.2014.07.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Meta-analysis of the quantitative relation between pulse pressure and mean arterial pressure and cardiovascular risk in patients with diabetes mellitus.2014

    • Author(s)
      Kodama S, Horikawa C, Fujihara K, Yoshizawa S, Yachi Y, Tanaka S, Ohara N, Matsunaga S, Yamada T, Hanyu O, Sone H.
    • Journal Title

      The American Journal of Cardiology

      Volume: 113 Issue: 6 Pages: 1058-1065

    • DOI

      10.1016/j.amjcard.2013.12.005

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association of Helicobacter Pylori Infection with Glycemic Control in Patients with Diabetes: A Meta-analysis2014

    • Author(s)
      Horikawa C, Kodama S, Fujihara K, Yachi Y, Tanaka S, Suzuki A, Hanyu O, Shimano H, Sone H
    • Journal Title

      J Diab Res

      Volume: - Pages: 250620-250620

    • DOI

      10.1155/2014/250620

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Second trimester postload glucose level as an important predictor of low birth weight infants: Tanaka Women's Clinic Study2014

    • Author(s)
      Yachi Y, Tanaka Y, Nishibata I, Yoshizawa S, Fujihara K, Kodama S, Suzuki A, Hanyu O, Sone H
    • Journal Title

      Diabetes Res Clin Pract

      Volume: 105 Issue: 3 Pages: e16-e19

    • DOI

      10.1016/j.diabres.2014.02.006

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] High cholesterol intake is associated with elevated risk of type 2 diabetes mellitus - a meta-analysis.2014

    • Author(s)
      Tajima R, Kodama S, Hirata M, Horikawa C, Fujihara K, Yachi Y, Yoshizawa S, Iida KT, Sone H.
    • Journal Title

      Clinical Nutrition

      Volume: 33 (6) Issue: 6 Pages: 946-50

    • DOI

      10.1016/j.clnu.2014.03.001

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 健常妊婦における栄養と妊娠経過に関する中間解析.2013

    • Author(s)
      谷内洋子、曽根博仁
    • Journal Title

      栄養学雑誌

      Volume: 71 Pages: 242-252

    • NAID

      130004553519

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diabetes and risk of hearing impairment in adults: a meta-analysis2013

    • Author(s)
      Horikawa C, Kodama S, Tanaka S, Fujihara K, Hirasawa R, Yachi Y, Shimano H, Yamada N, Saito K, Sone H
    • Journal Title

      J Clin EndocrinoI Metab

      Volume: 98(1) Issue: 1 Pages: 51-58

    • DOI

      10.1210/jc.2012-2119

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Body Weight Change and Type 2 Diabetes2013

    • Author(s)
      Kodama S, Horikawa C, Yoshizawa S, Fujihara K, Yachi Y, Tanaka S, Suzuki A, Hanyu O, Yagyu H, Sone H
    • Journal Title

      Epidemiology

      Volume: 24 Issue: 5 Pages: 778-9

    • DOI

      10.1097/ede.0b013e31829f6c31

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Use of high-normal levels of hemoglobin A1C and fasting plasma glucose for diabetes screening and prediction - A meta-analysis2013

    • Author(s)
      Kodama S, Horikawa C, Fujihara K, Hirasawa R, Yachi Y, Yoshizawa S, Tanaka S, Sone Y, Shimano H, Iida KT, Saito K, Sone H
    • Journal Title

      Diabetes Metab Res Rev

      Volume: 29 Issue: 8 Pages: 680-92

    • DOI

      10.1002/dmrr.2445

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quality and accuracy of Internet information concerning a healthy diet2013

    • Author(s)
      Hirasawa R, Yachi Y, Yoshizawa S, Horikawa C, Heianza Y, Sugawara A, Sone Y, Kondo K, Shimano H, Saito K, Kodama S, Sone H.
    • Journal Title

      Int J Food Sci Nutr

      Volume: 64 Issue: 8 Pages: 1007-1013

    • DOI

      10.3109/09637486.2013.812620

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] An early pregnancy HbA1C predicts gestational diabetes independent of fasting glucose in Japanese pregnant women: TWC Study2015

    • Author(s)
      Yoko Yachi, Yasuhiro Tanaka, Ayumi Sugawara, Izumi Nishibata, Yoko Ibe, Fujihara Kazuya, Reiko Hirasawa, Satoru Kodama, Hirohito Sone
    • Organizer
      The 25th Annual Scientific Meeting of the Japan Epidemiological Association
    • Place of Presentation
      ウインクあいち
    • Year and Date
      2015-01-21 – 2015-01-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] 妊娠中期における身体活動が糖代謝に与える影響の検討 (TWC Study)2014

    • Author(s)
      谷内洋子、田中康弘、西端泉、広瀬歩美、藤原和哉、児玉暁、曽根博仁
    • Organizer
      第 30 回日本糖尿病・妊娠学会年次学術集会
    • Place of Presentation
      長崎ブリックホール
    • Year and Date
      2014-11-28 – 2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 日本人妊婦325名における、妊娠早期の炭水化物摂取量と50g糖負荷試験陽性リスクの関連2014

    • Author(s)
      田島諒子、飯田薫子、穴迫唯衣、田中康弘、曽根博仁、谷内洋子
    • Organizer
      第36回日本臨床栄養学会総会
    • Place of Presentation
      JPタワー ホール&カンファレンス
    • Year and Date
      2014-10-04 – 2014-10-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 日本人女性の妊娠前後の体型および栄養摂取が母児の健康に及ぼす影響の検証-奨励賞受賞講演-2014

    • Author(s)
      谷内洋子
    • Organizer
      栄養改善学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-08-20 – 2014-08-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 妊娠初期HbA1c値および空腹時血糖値と妊娠糖尿病発症との関連の検討(TWC Study)2014

    • Author(s)
      谷内洋子、田中康弘、西端泉、広瀬歩美、児玉暁、齋藤和美、曽根博仁
    • Organizer
      第3回日本DOHaD研究会学術集会
    • Place of Presentation
      国立成育医療研究センター
    • Year and Date
      2014-07-25 – 2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 妊娠中期の身体活動量が糖代謝に及ぼす影響の検討(TWC Study)2014

    • Author(s)
      谷内洋子、田中康弘、西端泉、由澤咲子、藤原和哉、児玉暁、鈴木亜希子、羽入修、曽根博仁
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-05-22 – 2014-05-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 問診による糖尿病予測能のメタ解析2014

    • Author(s)
      由澤咲子、児玉暁、藤原和哉、堀川千嘉、菅原歩美、谷内洋子、山田貴穂、鈴木亜希子、羽入修、曽根博仁
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-05-22 – 2014-05-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 糖尿病患者における、ヘリコバクター・ピロリ菌感染とその除菌成功率:メタアナリシスによる報告2014

    • Author(s)
      堀川千嘉、児玉暁、藤原和哉、谷内洋子、羽入修、島野仁、曽根博仁
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-05-22 – 2014-05-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Second trimester postload glucose level as an important predictor of low birth weight infants2014

    • Author(s)
      谷内洋子、田中康弘、曽根博仁
    • Organizer
      第66回日本産婦人科学会学術講演会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2014-04-18 – 2014-04-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 妊娠中の母体の血糖状態と低出生体重児出産との関連(TWC Study)2014

    • Author(s)
      谷内洋子、田中康弘、西端泉、由澤咲子、藤原和哉、児玉暁、鈴木亜希子、羽入修、曽根博仁
    • Organizer
      第24回日本疫学会学術総会
    • Place of Presentation
      艮陵会館
    • Related Report
      2013 Research-status Report
  • [Presentation] 妊娠初期HbA1c値と妊娠糖尿病発症との関連の検討(TWC Study).2013

    • Author(s)
      谷内洋子, 田中康弘, 西端泉, 児玉暁, 鈴木亜希子,羽入修, 曽根博仁
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本市民会館
    • Related Report
      2013 Research-status Report
  • [Presentation] 母体の体重歴(二十歳時および妊娠時BMI)が母児の健康に及ぼす影響.2013

    • Author(s)
      谷内洋子, 田中康弘, 西端泉, 菅原歩美, 児玉暁, 鈴木亜希子, 羽入修, 曽根博仁
    • Organizer
      第2回日本DOHaD研究会 学術集会
    • Place of Presentation
      厚生労働省戸山研究庁舎
    • Related Report
      2013 Research-status Report
  • [Presentation] 妊娠初期空腹時血糖およびHbA1c値両者の同時測定は妊娠糖尿病発症を予測する指標として有用である(TWC Study).2013

    • Author(s)
      谷内洋子, 田中康弘, 西端泉, 由澤咲子, 藤原和哉, 児玉暁, 鈴木亜希子, 羽入修, 曽根博仁
    • Organizer
      第29回日本糖尿病・妊娠学会年次学術集会
    • Place of Presentation
      長良川国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] Relationship between Diabetic Neuropathy and Sleep Apnea Syndrome-A Meta-Analysis2013

    • Author(s)
      KAZUYA FUJIHARA, SATORU KODAMA, CHIKA HORIKAWA, AYUMI SUGAWARA, YORIKO HEIANZA, YOKO YACHI, KAZUMI SAITO, HITOSHI SHIMANO, OSAMU HANYU, HIROHITO SONE
    • Organizer
      73rd American Diabetes Association Scientific Sessions.
    • Place of Presentation
      Chicago, US
    • Related Report
      2013 Research-status Report
  • [Presentation] Relationship between Body Weight (BW) Gain from Early Adulthood and Incident Type 2 Diabetes (T2DM)-A Meta-Analysis2013

    • Author(s)
      SATORU KODAMA, CHIKA HORIKAWA, KAZUYA FUJIHARA, RYOKO TAJIMA, YORIKO HEIANZA, REIKO HIRASAWA, YOKO YACHI, KAORUKO T. IIDA, HITOSHI SHIMANO, OSAMU HANYU, HIROHITO SONE
    • Organizer
      73rd American Diabetes Association Scientific Sessions.
    • Place of Presentation
      Chicago, US
    • Related Report
      2013 Research-status Report
  • [Presentation] HbA1C in the First Trimester Predicts Gestational Diabetes Independent of Fasting Glucose in Japanese Pregnant Women: TWC Study2013

    • Author(s)
      Yoko Yachi, Yasuhiro Tanaka, Ayumi Sugawara, Izumi Nishibata, Chika Horikawa, Yoriko Heianza, Fujihara Kazuya, Satoru Kodama, Osamu Hanyu, Hirohito Sone
    • Organizer
      73rd American Diabetes Association Scientific Sessions.
    • Place of Presentation
      Chicago, US
    • Related Report
      2013 Research-status Report
  • [Presentation] Low Eradication Rate of Helicobacter Pylori (HP) in Patients with Diabetes: A Meta-Analysis2013

    • Author(s)
      CHIKA HORIKAWA, SATORU KODAMA, SAKIKO YOSHIZAWA, KAZUYA FUJIHARA, RYOKO TAJIMA, YOKO YACHI, AKIKO SUZUKI, OSAMU HANYU, HITOSHI SHIMANO, HIROHITO SONE
    • Organizer
      73rd American Diabetes Association Scientific Sessions.
    • Place of Presentation
      Chicago, US
    • Related Report
      2013 Research-status Report
  • [Presentation] Predictive ability of simple clinical information without blood tests for future incident diabetes: a meta-analysis.2013

    • Author(s)
      S. Yoshizawa, S. Kodama, K. Fujihara, C. Horikawa, A. Sugawara, Y. Heianza, Y. Yachi, S. Tanaka, S. Minakawa, T. Yamada, A. Suzuki, O. Hanyu, H. Sone
    • Organizer
      49th European Association for the Study of Diabetes.
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2013 Research-status Report
  • [Book] コンパクト 臨床栄養学2014

    • Author(s)
      長浜幸子、近藤雅雄、谷内洋子ほか
    • Publisher
      朝倉書店
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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