The association vitamin D status and locomotive syndrome
| Project/Area Number |
25750061
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | Osaka Shoin Women's University |
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Principal Investigator |
KUWABARA Akiko 大阪樟蔭女子大学, 健康栄養学部, 准教授 (00582602)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | ビタミンD / 骨格筋量 / 筋力 / MRI / 血清25水酸化ビタミンD濃度 / 四肢筋肉量 / 下肢筋力 / サルコペニア / 核磁気共鳴装置 |
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| Outline of Final Research Achievements |
To examine the the association between vitamin D status and sarcopenia, we have performed two cross-sectional studies; one for healthy 43 institutionalized elderly subjects and one for 40 middle-aged healthy adults to study the role of vitamin D on muscle strength and physical activity.
In multiple regression analysis, serum 25-hydroxyvitamin D (25OHD) level was a significant positive factor for physical performance in elderly subjects and for lower limb muscle strength in middle-aged adults. However, serum 25OHD level did not significantly contribute to the skeletal muscle mass index (SMI) in either study.
Muscle strength is composed of muscle mass and the quality of muscle, such as fat filtration of muscle. Since our study suggested that serum 25OHD level were more strongly correlated with the quality of muscle compared with muscle mass, further studies evaluating fat filtration of muscle by magnetic resonance imaging (MRI) are required to perform.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] High prevalence of vitamin D deficiency in patients with xeroderma pigmetosum (XP)- A under strict sun-protection2015
Author(s)
Kuwabara A, Tsugawa N, Tanaka K, Uejima Y, Ogawa J, Otao N, Yamada N, Masaki T, Nishigori C, Moriwaki S, Okano T.
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Journal Title
European Journal of Clinical Nutrition
Volume: Epub ahead of print
Issue: 6
Pages: 693-9
DOI
Related Report
Peer Reviewed
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[Presentation] High prevalence of vitamin D deficiency in patients with xeroderma pigmetosum (XP)- A under strict sun-protection2014
Author(s)
Kuwabara A, Tsugawa N, Uejima Y, Ogawa J, Otao N, Yamada N, Tanaka K, Masaki T, Nishigori C, Moriwaki S, Okano T.
Organizer
American Society for Bone and Mineral Research 36th Annual Meeting
Place of Presentation
Houston, Texas, USA
Year and Date
2014-09-12 – 2014-09-15
Related Report
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