| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Atopic dermatitis (AD) is a common inflammatory disease of the skin, which is characterized by xerosis, pruritus, and erythematous lesions. AD arises as a result of the interaction between environmental and genetic factors. Especially, epidermal barrier dysfunction caused by genetic barrier defects is a primary event in the development of AD. In this study, we planned to develop the novel topical device which had the skin barrier protection and anti-inflammatory effect, consisting of candidate material A and B, and evaluated the efficacy of this device using the model mouse which exhibited AD-like lesions.
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