• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of hybrid-scafflod by titanium micro-porous structures and modified titaniumu gel surfaces

Research Project

Project/Area Number 25750162
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionThe University of Tokushima

Principal Investigator

SEKINE Kazumitsu  徳島大学, 大学院医歯薬学研究部, 講師 (50447182)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsスキャフォールド / 多孔性材料 / 表面改質 / 生体親和性 / 血液適合性 / チタン製材料 / マイクロ多孔体 / チタンインプラント
Outline of Final Research Achievements

The main theme of this project was the development of hybrid titanium scaffold, with the customizing process of micro-porous structure and the surface modification of titanium-gel and amino acid fixation.
To show the advantage of porous structures, we have studied the cell compatibility tests with fibroblast cell, and the pull-out study against the connective tissue by animal experiments. About the titanium-gel’s specifications study, we’ve arranged adequate acidifications and the amino acid fixative protocol, and then evaluated by the spectroscopy and in vitro cell adhesion studies. Those results indicated the possibility and usefulness of these structural and chemical modified applications for the scaffold devices.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (6 results)

  • [Journal Article] 細胞賦活効果を狙ったチタン表面処理法2014

    • Author(s)
      関根一光
    • Journal Title

      四国歯学会雑誌

      Volume: 26 Pages: 49-54

    • NAID

      120005832490

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 早期内膜新生を狙ったチタン多孔質スキャフォールドの作成と評価2015

    • Author(s)
      関根一光 内藤禎人 市川哲雄 裵志英 浜田賢一
    • Organizer
      第37回日本バイオマテリアル学会大会
    • Place of Presentation
      京都テルサ(京都府・京都市)
    • Year and Date
      2015-11-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] DEVELOPMENT OF MICRO-POROUS TITANIUM SCAFFOLD FOR PROMOTING THE EARLY NEOINTIMAL GROWTH2014

    • Author(s)
      K. Sekine, J.Y. Bae, Y. Naito, T. Ichikawa, K. Hamada
    • Organizer
      Materials Today Asia 2014
    • Place of Presentation
      香港(中国)
    • Year and Date
      2014-12-09 – 2014-12-12
    • Related Report
      2014 Research-status Report
  • [Presentation] チタン微粒子焼結と表面改質による血管内皮誘導を目的としたチタン多孔質体の開発2014

    • Author(s)
      関根一光、Bae Ji-Young、内藤禎人、市川哲雄、浜田賢一
    • Organizer
      第52回日本人工臓器学会大会
    • Place of Presentation
      京王プラザホテル札幌(北海道・札幌市)
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Development and evaluation of micro-porous titanium scaffold for promoting neointimal growth as the blood contacting surface2014

    • Author(s)
      K. Sekine, Y. Naito, T. Ichikawa, J.Y. Bae, K. Hamada
    • Organizer
      第53回日本生体医工学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2014-06-24 – 2014-06-26
    • Related Report
      2014 Research-status Report
  • [Presentation] Fundamental studies of micro-porous titanium scaffold for obtaining the neointimal formation.2013

    • Author(s)
      K. Sekine, J.Y. Bae, Y. Naito, T. Ichikawa, K. Hamada
    • Organizer
      5th Congress of the International Federation for Artificial Organs
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2013 Research-status Report
  • [Presentation] Fundamental studies and development of micro-porous titanium blood contacting surface obtaining the neointimal formation.2013

    • Author(s)
      K. Sekine, Y. Naito, K. Hamada
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi